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Antibacterial Activity: Triclosan exhibits broad-spectrum antibacterial activity, which means it can inhibit the growth of a wide range of bacteria. It disrupts bacterial cell membranes and inhibits fatty acid synthesis, leading to bacterial cell death.
Dental Health: Triclosan is often added to toothpaste and mouthwash for its ability to prevent dental plaque formation and reduce gingivitis. It can help maintain oral hygiene and reduce the risk of tooth decay and gum disease.
Skin Health: Triclosan is used in some soaps and skincare products due to its antibacterial properties. It may help reduce bacterial contamination on the skin and prevent skin infections, particularly in healthcare settings.
Household Products: Triclosan is also found in some household products, such as cleaning agents and laundry detergents, to inhibit the growth of bacteria and fungi on surfaces and fabrics.
Emerging Concerns: Despite its widespread use, triclosan has raised concerns due to its potential adverse health effects and environmental impact. Some studies suggest that triclosan may disrupt hormonal regulation in animals and humans, leading to endocrine disruption. It has also been associated with antibiotic resistance, although the extent of its contribution to resistance in clinical settings is debated.
Skin Irritation: Triclosan can cause skin irritation and allergic reactions in some individuals, particularly those with sensitive skin. Prolonged or excessive exposure to triclosan-containing products may exacerbate skin conditions such as eczema or dermatitis.
Environmental Impact: Triclosan is persistent in the environment and has been detected in waterways, soil, and aquatic organisms. It can bioaccumulate in the food chain and may pose risks to aquatic ecosystems. Concerns about triclosan's environmental impact have led to regulatory restrictions and bans on its use in some countries.
Regulatory Actions: In response to concerns about its safety and environmental impact, regulatory agencies in various countries have taken measures to restrict or ban the use of triclosan in consumer products. For example, the U.S. Food and Drug Administration (FDA) banned the use of triclosan in over-the-counter consumer antiseptic wash products in 2016.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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