🍽️ enoxacin (antibiotic)

Treatment of Bacterial Infections: Enoxacin is used to treat various bacterial infections, including urinary tract infections (UTIs), respiratory tract infections, skin and soft tissue infections, bone and joint infections, and sexually transmitted infections (STIs) such as gonorrhea.

Gram-Negative and Gram-Positive Coverage: Enoxacin exhibits activity against both Gram-negative and Gram-positive bacteria. It can target pathogens such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, Streptococcus pneumoniae, and others.

UTIs and Prostatitis: Enoxacin is particularly effective in treating urinary tract infections, including complicated and uncomplicated UTIs, as well as prostatitis (inflammation of the prostate gland) caused by susceptible bacteria.

Respiratory Infections: It can be used to treat respiratory tract infections, including bronchitis and pneumonia caused by susceptible bacteria.

Skin and Soft Tissue Infections: Enoxacin may be prescribed for skin and soft tissue infections, such as cellulitis and wound infections, when caused by susceptible organisms.

Bone and Joint Infections: In some cases, enoxacin can be used to treat bone and joint infections caused by susceptible bacteria, although it may not be the first-line choice for these infections.

Gonorrhea: Enoxacin was previously used to treat gonorrhea, but its use has decreased due to the emergence of resistant strains. It may still be effective against some gonorrhea strains in regions where resistance rates are low.

Side Effects: Like other fluoroquinolone antibiotics, enoxacin can cause various side effects, including gastrointestinal symptoms (nausea, vomiting, diarrhea), central nervous system effects (headache, dizziness, insomnia), and musculoskeletal effects (tendonitis, tendon rupture). Rare but serious adverse effects include peripheral neuropathy, hypersensitivity reactions, and potentially irreversible damage to tendons, muscles, joints, nerves, and the central nervous system.

Drug Interactions: Enoxacin may interact with other medications, including antacids, sucralfate, iron supplements, and certain anticoagulants, potentially reducing its absorption or efficacy.

Precautions: Enoxacin should be used with caution in patients with a history of seizures, renal impairment, myasthenia gravis, or other neurological disorders. It is generally not recommended for use in children, pregnant women, or breastfeeding mothers unless the benefits outweigh the risks.