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Fungal Skin Infections: Clotrimazole is commonly used to treat fungal skin infections such as athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It works by inhibiting the growth and multiplication of fungal organisms responsible for these infections, thereby relieving symptoms such as itching, redness, scaling, and discomfort. Clotrimazole is available in various formulations, including creams, lotions, sprays, and powders, for topical application to the affected skin areas.
Yeast Infections: Clotrimazole is also used to treat yeast infections, particularly vaginal yeast infections (vulvovaginal candidiasis) caused by Candida species. It is available in vaginal cream or suppository formulations for intravaginal use. Clotrimazole helps eliminate yeast overgrowth and restore the natural balance of microorganisms in the vaginal flora, thereby relieving symptoms such as vaginal itching, burning, discharge, and discomfort.
Oral Thrush: Clotrimazole may be used to treat oral thrush (oral candidiasis), a fungal infection of the mouth and throat caused by Candida species. It is available in oral troche (lozenge) or oral suspension formulations for local application to the affected oral mucosa. Clotrimazole helps reduce the growth of yeast in the mouth, throat, and esophagus, thereby alleviating symptoms such as white patches or plaques, soreness, and difficulty swallowing.
Nail Fungus: Clotrimazole is sometimes used off-label in the treatment of nail fungus (onychomycosis), although it is less commonly prescribed for this indication compared to other antifungal medications. It may be used in combination with other antifungal agents or as part of topical therapy for superficial nail infections caused by dermatophyte fungi. However, oral antifungal medications are generally preferred for the treatment of more severe or resistant cases of nail fungus.
Dosage and Administration: The dosage and duration of clotrimazole therapy depend on the specific fungal infection being treated, the severity of symptoms, and the individual patient's response to treatment. Clotrimazole formulations are applied topically to the affected skin areas, vaginal mucosa, oral mucosa, or nails as directed by the healthcare provider. Treatment may range from a few days to several weeks, depending on the type and location of the infection.
Side Effects: Common side effects of clotrimazole may include mild skin irritation, itching, burning, or redness at the site of application. These side effects are usually transient and resolve with continued use or upon discontinuation of the medication. Allergic reactions to clotrimazole are rare but may manifest as severe skin irritation, rash, or swelling. Patients should discontinue use and seek medical attention if they experience signs of an allergic reaction.
Contraindications and Precautions: Clotrimazole is generally well-tolerated and safe for most individuals when used as directed. It is contraindicated in individuals with known hypersensitivity to clotrimazole or any of its components. Clotrimazole should be used with caution in patients with open wounds, mucosal ulcerations, or known immune deficiencies. It is for external use only and should be kept away from eyes, nose, mouth, and other mucous membranes to avoid irritation or adverse effects.
(abzorb, abzorb dusting, acrozol, adco-normospor, aflorix, afun, agisten, aknecolor, albican, amaze, antifungol, antifungol 1%, antifungol hexal, antifungol hexal 1%, antimicotico, apocanda, apo-clotrimazole, a-por, aristen, arnela, aurizon, axasol x2, bacimyc, baycuten, baycuten hc, baycuten-n, beclotis-c, beclotrim, bernesten, beta micoter, betaclosone, betamazole, betavate-cl, betazole, bet-cl, betnovate-cl, betson-cl, blomozol, boots antifungal, boots thrush 1%, boots thrush duo, camazole, camysten, canalba, canasone c.b., canazol, canazol lozenge, canazol-be, canazole, candacort, candaspor, candazole, candazole v, candexin, candibec, candibene, candibene 1%, candibene-teva, candid, candid-b, candid-tv, candid-v, candid-v1, candid-v6, candimax, candimon, candinox, candistan, candistan 1%, candistan 2%, candistat, candiva, candizole, candizole v, canemazole 1%, canesmed, canesoral combi-pak, canespie, canesten, canesten 1, canesten 1%, canesten 10%, canesten 2%, canesten 3, canesten af dual action, canesten clotrimazol, canesten clotrimazole, canesten combi, canesten dual action 1%, canesten duo, canesten fluconazole and clotrimazole duo, canesten gyn, canesten gyn once kombi, canesten gyno, canesten hc, canesten hydrocortisone, canesten internal 10%, canesten plus, canesten thrush, canesten thrush combi, canesten v, canesten vt, canesten1 vc, canestene gyn clotrimazole, canesten-hc, canesten-s, canestin, canestol, canex t, canex v, canfem, cangil, canifug, canifug 1%, canifug 2%, canifug cremolum, canifug cremolum kombi, canifug-losung 1%, caninil, canison, canison-b, cansen, cansten, canvag, cb, cipzol, clarizol, clenorush, clobe, cloben, clocreme, clodai, cloderm, cloderm 1%, clo-ekarzin, clofusone, clomazen, clomazol, clomazol-3, clomazole, clomazole vag tab, clomelon, clorid-b, clorifort, clortilen, closol 1%, closon, closone, clostrin 1%, clothree, clotison, clotrasone, clotrazil, clotri, clotri opt, clotri-denk, clotrigalen, clotrikad, clotrikam-v, clotrim, clotrimaderm, clotrimaderm 2%, clotrimazol, clotrimazol - betametasona l.ch., clotrimazol + betametasona andromaco, clotrimazol + betametasona ecuaquimica, clotrimazol + betametasona mintlab, clotrimazol + betametasona sanitas, clotrimazol 1%, clotrimazol 1% - 1 a pharma, clotrimazol 1% la sante, clotrimazol 1% opko, clotrimazol abz, clotrimazol al, clotrimazol al 1%, clotrimazol al 2%, clotrimazol andromaco, clotrimazol anglopharma, clotrimazol antibiotice, clotrimazol aristo 1%, clotrimazol aristo 2%, clotrimazol basi, clotrimazol bayfarma, clotrimazol biofarm, clotrimazol colmed, clotrimazol ecuaquimica, clotrimazol farmandina, clotrimazol farmoz, clotrimazol genamΓ©rica, clotrimazol genfar, clotrimazol gsk, clotrimazol hbf, clotrimazol helvepharm, clotrimazol heumann, clotrimazol hyperion, clotrimazol ilab, clotrimazol kronos, clotrimazol l.ch., clotrimazol la santΓ©, clotrimazol labesfal, clotrimazol magistra, clotrimazol mintlab, clotrimazol mk, clotrimazol mylan, clotrimazol pasteur, clotrimazol ramos, clotrimazol ratiopharm 1%, clotrimazol raymos, clotrimazol rph, clotrimazol slavia, clotrimazol terpol, clotrimazol teva, clotrimazol winthrop, clotrimazol zentiva, clotrimazol-ct, clotrimazole 1% p d, clotrimazole and betamethasone dipropionate actavis, clotrimazole and betamethasone dipropionate fougera, clotrimazole bionika, clotrimazole europharm, clotrimazole farmaprim, clotrimazole medana, clotrimazole om, clotrimazole panbiotic, clotrimazole pharco, clotrimazole protech, clotrimazole t3a, clotrimazole taro, clotrimazole tsiteli a, clotrimazole vag tab, clotrimazole-akri, clotrimazolo farmakopea, clotrimazolo fg, clotrimazolum, clotrimazolum aflofarm, clotrimazolum amara, clotrimazolum gsk, clotrimazolum hasco, clotrimazolum medana, clotrimazolum sanitas, clotrimazolum ziaja, clotrimin, clotrimin-b, clotrinolon, clotri-q, clotrisone, clotrix, clotrizol, clovamark, clozol, clozole, clozosone, clozox, corisol, cotren, cotrisan, creminem, creminem b, cruex, ctl, cutamycon, cutanil, cutistad 1%, defungo, dequazol t, dermasim, dermatin, dermatin 1%, dermatin cort, dermicin, dermicin b, dermicol, dermifar, dermizole, derzid-c, desamix effe, desenex, diomicete, donomix, dr. scholl's, elcid, empecid, empecid 1%, empecid gyno, exfung, eximius, factodin, fango, fango-b, fastin, femazole duo, fiasole, flotiran, fluol, fluol-b, formei, fucodine, fugolin, fungi cure intensive, fungicare, fungicide, fungicur, fungiderm, fungiderm v.t., fungiderm-b, fungidermin, fungidexan, fungin, fungin-b, fungizid-ratiopharm, fungocop, fungos, fungotopic, fungotox, gilt, gine canesten, gineintima clotriactive, gino-canesten, ginolotricomb, gixaderm, glenmark clotrimazole, gromazol, gyne-lotremin, gyne-lotrimin, gynesol, gyno canesten, gyno canesten-1, gynocanesten, gyno-canesten, gynostatum, gynox, hongoper, h-trimazole, hydroagisten, ikolan, imazol, imazol plus, imidil, imidil plus, jenamazol, jenamazol jenapharm, kadefungin, kamicin, kanezin, kansel, kansel-b, kansen, kemeizuo - aoyipollen, klomazole, klotrimasool gsk, klotrimazol, klotrimazolis, kotozole, kotozole 1%, krema rosa, liferzol v, lin guan, locasten, locasten 1%, locasten 2%, locrim, lomecan v, lotremin, lotricomb, lotriderm, lotrimin af, lotrisone, manomazole, marbodex, medaspor, medifungol, micoclin, micolysin, micomazol, micomazol b, micomazol deo, micosan, micosep, micosep b, micosep deo, micosten, micoter, modvate-af, morzin, mycanden, mycelex, mycoderm-c, mycofug, mycohydralin, mycopar-c, mycoril, mycoril 1%, mycosten, mycozole, mycozole-b, mycuten d, myko cordes, myko cordes plus, mykofungin, mykohaug 3 kombi, mykohaug c, mykohaug c3, nalbix, neosten, neosten hc, neverfungol, nifugal, nifugal-b, ninerlnin, noah smearing film, norotic for dogs, notiderm nf, novacetol, novadrel, novarnela, omastin duo, oni, opizole, opizole b, opizole-b, oralten, otrix, patylcrem, perfungol, p-gyzole, pharmaniaga betamethasone clo, piesan, plimycol, prubagen, prurinon, safelon, sd-hermal, selsyd, selsyd-b, sinamida, sinfung, stadmazol, statum, statum-b, surfaz, taon 1%, telugren, telugren plus, tinatrim, topibet-cl, tribesona, triderm-c, tridermsone, trimazol, trimazole, truecand, undex clotrimazol, uro-gyn, vaff, vagil, vagisan myko kombi, vanesten, veltrim 1%, yeastazol, yuhealfu, zema, zenesten, zhengmeiting)
Rank | Probiotic | Impact |
---|---|---|
genus | Bifidobacterium | Reduces |
species | Bacteroides uniformis | Reduces |
species | Bifidobacterium adolescentis | Reduces |
species | Bifidobacterium longum | Reduces |
species | Escherichia coli | Reduces |
species | Lacticaseibacillus paracasei | Reduces |
species | Parabacteroides distasonis | Reduces |
subspecies | Bifidobacterium longum subsp. infantis | Reduces |
subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
2 | 0 | Escherichia coli | species | Decreases |
1 | 0 | Streptococcus parasanguinis | species | Decreases |
1 | 0 | Veillonella parvula | species | Decreases |
1 | 0 | [Ruminococcus] torques | species | Decreases |
1 | 0 | Agathobacter rectalis | species | Decreases |
1 | 0 | Bacteroides caccae | species | Decreases |
1 | 0 | Bacteroides fragilis | species | Decreases |
1 | 0 | Bacteroides ovatus | species | Decreases |
1 | 0 | Bacteroides thetaiotaomicron | species | Decreases |
1 | 0 | Bacteroides uniformis | species | Decreases |
1 | 0 | Bacteroides xylanisolvens | species | Decreases |
1 | 0 | Bifidobacterium adolescentis | species | Decreases |
1 | 0 | Bifidobacterium longum | species | Decreases |
1 | 0 | Blautia obeum | species | Decreases |
1 | 0 | Clostridioides difficile | species | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.9 | 0.9 | |
Acne | 0.6 | 0.9 | -0.5 |
ADHD | 5.1 | 0.6 | 7.5 |
Age-Related Macular Degeneration and Glaucoma | 1.1 | 0.4 | 1.75 |
Allergic Rhinitis (Hay Fever) | 3.4 | 2.9 | 0.17 |
Allergies | 7.5 | 3.5 | 1.14 |
Allergy to milk products | 1.8 | 1.6 | 0.13 |
Alopecia (Hair Loss) | 1.6 | 1.6 | |
Alzheimer's disease | 6.3 | 8.3 | -0.32 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 3.2 | 0.8 | 3 |
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