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🍽️ toremifene,(prescription)

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  1. Breast Cancer: Toremifene is classified as a selective estrogen receptor modulator (SERM). It works by blocking the effects of estrogen in breast tissue, thereby inhibiting the growth of estrogen-dependent breast cancer cells. Toremifene is indicated for the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive tumors. It may also be used as adjuvant therapy to reduce the risk of breast cancer recurrence following surgery or other primary treatments.

  2. Estrogen Receptor-Positive Breast Cancer: Toremifene is particularly effective in treating estrogen receptor-positive breast cancer, where estrogen promotes the growth of cancer cells. By blocking estrogen receptors in breast tissue, toremifene helps slow down or stop the progression of hormone-sensitive breast cancer.

  3. Metastatic Breast Cancer: Toremifene is used in the treatment of metastatic breast cancer, where cancer cells have spread to other parts of the body beyond the breast. It may help slow down the progression of the disease and alleviate symptoms associated with advanced breast cancer.

  4. Adjuvant Therapy: Toremifene may be prescribed as adjuvant therapy in combination with other treatments such as surgery, chemotherapy, or radiation therapy. Adjuvant therapy aims to reduce the risk of cancer recurrence and improve long-term outcomes in patients who have undergone primary treatment for breast cancer.

  5. Bone Health: Toremifene has been shown to have beneficial effects on bone health in postmenopausal women with breast cancer. It may help prevent bone loss and reduce the risk of osteoporosis, a common complication of breast cancer treatment and menopause.

  6. Endometrial Cancer: Like other SERMs, toremifene may increase the risk of endometrial cancer or uterine abnormalities in some women. Regular gynecological monitoring is recommended during treatment with toremifene to detect any potential changes in the uterus and endometrium.

  7. Thromboembolic Events: Toremifene, similar to other SERMs, may increase the risk of thromboembolic events such as blood clots in veins (deep vein thrombosis) or arteries (pulmonary embolism). Patients should be monitored for signs and symptoms of thromboembolism during treatment.

  8. Hot Flashes: Toremifene may cause or exacerbate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. These side effects are often transient and may improve over time or with supportive measures.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of toremifene,(prescription) On Probiotics

Rank Probiotic Impact
genus Bacillus Reduces
genus Bifidobacterium Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium bifidum Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium catenulatum Reduces
species Bifidobacterium longum Reduces
species Blautia hansenii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Faecalibacterium prausnitzii Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Lactococcus lactis Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by toremifene,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Roseburia genus Decreases
0 1 Agathobacter genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Segatella genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Collinsella genus Decreases
0 1 Coprococcus genus Decreases
0 1 Lachnospira genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Dorea genus Decreases
0 1 Blautia genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Bilophila genus Decreases
0 1 Streptococcus genus Decreases
0 1 Bacteroides genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Clostridioides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Enterocloster genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Parolsenella genus Decreases
0 1 Wujia genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Leyella genus Decreases
0 1 Wansuia genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Simiaoa genus Decreases
0 1 Christensenella genus Decreases
0 1 Olsenella genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Massilistercora genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Qiania genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Treponema genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Faecalibacillus genus Decreases
0 1 Anaerostipes genus Decreases
0 1 Eubacterium genus Decreases
0 1 Prevotella genus Decreases
0 1 Marvinbryantia genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Vescimonas genus Decreases
0 1 Longicatena genus Decreases
0 1 Mageeibacillus genus Decreases
0 1 Adlercreutzia genus Decreases
0 1 Fannyhessea genus Decreases
0 1 Bacillus genus Decreases
0 1 Oscillibacter genus Decreases
0 1 Lactococcus genus Decreases
0 1 Faecalibacterium genus Decreases
0 1 Monoglobus genus Decreases
0 1 Faecalibaculum genus Decreases
0 1 Fusobacterium genus Decreases
1 0 Clostridioides difficile species Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Blautia obeum species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Coprococcus comes species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia hominis species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Segatella copri species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
1 0 Bifidobacterium adolescentis species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Coprococcus catus species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Dorea longicatena species Decreases
0 1 Segatella bryantii species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Streptococcus parasanguinis species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Leyella stercorea species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Parolsenella catena species Decreases
0 1 Blautia liquoris species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Wujia chipingensis species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Christensenella minuta species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Bacteroides sp. A1C1 species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Flavonifractor plautii species Decreases
0 1 Blautia argi species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Bacteroides sp. HF-162 species Decreases
0 1 Blautia parvula species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Enterocloster clostridioformis species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Actinomyces oris species Decreases
0 1 Streptococcus suis species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Treponema peruense species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Parvimonas micra species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Hungatella hathewayi species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Streptococcus australis species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Prevotella intermedia species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Parabacteroides johnsonii species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Eubacterium limosum species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Treponema denticola species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Leyella lascolaii species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Anaerostipes caccae species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Romboutsia ilealis species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Ruthenibacterium lactatiformans species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Blautia pseudococcoides species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
0 1 Emergencia timonensis species Decreases
0 1 [Clostridium] scindens species Decreases
0 1 Bifidobacterium bifidum species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Blautia hansenii species Decreases
0 1 Paraprevotella clara species Decreases
0 1 Prevotella bivia species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Blautia producta species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Romboutsia sp. 13368 species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Enterocloster asparagiformis species Decreases
0 1 Alistipes communis species Decreases
0 1 Streptococcus pasteurianus species Decreases
0 1 [Clostridium] innocuum species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Butyricimonas virosa species Decreases
0 1 Lactococcus lactis species Decreases
0 1 Dysosmobacter welbionis species Decreases
0 1 Prevotella dentalis species Decreases
0 1 Thomasclavelia ramosa species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Bacteroides ovatus species Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of toremifene,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 1.2 1.2
Acne 0.3 -0.3
ADHD 4.6 1.1 3.18
Age-Related Macular Degeneration and Glaucoma 1.2 0.5 1.4
Allergic Rhinitis (Hay Fever) 3.5 2.7 0.3
Allergies 6.4 3.5 0.83
Allergy to milk products 2.3 1.4 0.64
Alopecia (Hair Loss) 2.5 0.2 11.5
Alzheimer's disease 6.2 8.5 -0.37
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.9 0.7 3.14
Ankylosing spondylitis 4.6 2.2 1.09
Anorexia Nervosa 2.1 4.2 -1
Antiphospholipid syndrome (APS) 1.6 0.4 3
Asthma 5.2 2.6 1
Atherosclerosis 3 1.3 1.31
Atrial fibrillation 5.3 3.3 0.61
Autism 9.8 10.4 -0.06
Autoimmune Disease 0.8 0.9 -0.13
Barrett esophagus cancer 0 0.4 0
benign prostatic hyperplasia 0.5 -0.5
Biofilm 1.6 1.6
Bipolar Disorder 2.2 1.7 0.29
Brain Trauma 1.5 2.1 -0.4
Breast Cancer 0 0
Cancer (General) 0.1 2.3 -22
Carcinoma 4.7 3.7 0.27
Celiac Disease 3.3 4.5 -0.36
Cerebral Palsy 1.3 2.1 -0.62
Chronic Fatigue Syndrome 5.8 8.4 -0.45
Chronic Kidney Disease 4.4 4.2 0.05
Chronic Lyme 0.6 0.9 -0.5
Chronic Obstructive Pulmonary Disease (COPD) 2.2 2.2 0
Chronic Urticaria (Hives) 0.4 1.5 -2.75
Coagulation / Micro clot triggering bacteria 1.1 2.5 -1.27
Cognitive Function 3.5 1.6 1.19
Colorectal Cancer 6.9 3.2 1.16
Constipation 1.9 1.1 0.73
Coronary artery disease 3 4.1 -0.37
COVID-19 9.5 14.8 -0.56
Crohn's Disease 9.3 8.2 0.13
Cushing's Syndrome (hypercortisolism) 1 -1
cystic fibrosis 2.3 -2.3
d-lactic acidosis (one form of brain fog) 0.1 0.1
deep vein thrombosis 1.6 2.4 -0.5
Denture Wearers Oral Shifts 1.3 1.3
Depression 12 11.5 0.04
Dermatomyositis 0.4 0.3 0.33
Eczema 1.2 2.6 -1.17
Endometriosis 3.6 1.9 0.89
Eosinophilic Esophagitis 0.1 0.4 -3
Epilepsy 3.4 2.6 0.31
erectile dysfunction 0.5 0.4 0.25
Fibromyalgia 3.5 3 0.17
Functional constipation / chronic idiopathic constipation 6.2 5.7 0.09
gallstone disease (gsd) 3.4 1.1 2.09
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.6 2.2 -0.38
Generalized anxiety disorder 2.5 2.4 0.04
Glioblastoma 0.1 0.7 -6
Gout 1.3 0.5 1.6
Graves' disease 2.2 3.8 -0.73
Gulf War Syndrome 1.3 1.5 -0.15
Halitosis 1.2 0.4 2
Hashimoto's thyroiditis 4.3 2.7 0.59
Heart Failure 4.8 3.4 0.41
hemorrhagic stroke 1.1 1.1
Hidradenitis Suppurativa 1.9 1.9
High Histamine/low DAO 0.5 0.9 -0.8
hypercholesterolemia (High Cholesterol) 0.1 0.2 -1
hyperglycemia 0.8 1.7 -1.13
Hyperlipidemia (High Blood Fats) 1.5 0.6 1.5
hypersomnia 0.1 1.4 -13
hypertension (High Blood Pressure 6 8.2 -0.37
Hypothyroidism 0.4 1.7 -3.25
Hypoxia 1.7 0.1 16
IgA nephropathy (IgAN) 2.1 4.7 -1.24
Inflammatory Bowel Disease 7.1 12 -0.69
Insomnia 3.2 3.5 -0.09
Intelligence 1.6 1.2 0.33
Intracranial aneurysms 1.9 1.3 0.46
Irritable Bowel Syndrome 6.2 6.2 0
ischemic stroke 3.2 1.8 0.78
Juvenile idiopathic arthritis 0.1 0.1 0
Liver Cirrhosis 7.7 4.3 0.79
Long COVID 8.1 11.4 -0.41
Low bone mineral density 0.1 2 -19
Lung Cancer 0.4 1.7 -3.25
Mast Cell Issues / mastitis 0.4 1.4 -2.5
ME/CFS with IBS 1.1 3.4 -2.09
ME/CFS without IBS 1.3 2.6 -1
membranous nephropathy 0.5 0.5
Menopause 1.9 0.7 1.71
Metabolic Syndrome 8.9 9.9 -0.11
Mood Disorders 11.2 9.4 0.19
multiple chemical sensitivity [MCS] 1.1 0.5 1.2
Multiple Sclerosis 6.3 8 -0.27
Multiple system atrophy (MSA) 0.8 1.2 -0.5
myasthenia gravis 0.5 0.7 -0.4
neuropathic pain 2.8 -2.8
Neuropathy (all types) 0.9 1.1 -0.22
neuropsychiatric disorders (PANDAS, PANS) 0.4 0.1 3
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 5 6.6 -0.32
NonCeliac Gluten Sensitivity 1.6 0.8 1
Obesity 11.4 10.3 0.11
obsessive-compulsive disorder 6 5.2 0.15
Osteoarthritis 3.1 2.1 0.48
Osteoporosis 1.4 2.3 -0.64
pancreatic cancer 0.4 0.4 0
Parkinson's Disease 9.4 9.3 0.01
Polycystic ovary syndrome 8.2 3.6 1.28
Postural orthostatic tachycardia syndrome 0.8 -0.8
Premenstrual dysphoric disorder 1.2 0.5 1.4
primary biliary cholangitis 1.1 1.6 -0.45
Primary sclerosing cholangitis 1.6 4.4 -1.75
Psoriasis 3.6 4 -0.11
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 9.9 5 0.98
Rosacea 1.5 0.6 1.5
Schizophrenia 6.9 4.1 0.68
scoliosis 0.8 1.6 -1
sensorineural hearing loss 0.4 0.4
Sjögren syndrome 2.4 4.2 -0.75
Sleep Apnea 2.5 2 0.25
Slow gastric motility / Gastroparesis 1.1 0.5 1.2
Small Intestinal Bacterial Overgrowth (SIBO) 1.7 0.6 1.83
Stress / posttraumatic stress disorder 2.4 3 -0.25
Systemic Lupus Erythematosus 4.2 3.2 0.31
Tic Disorder 1.7 2.7 -0.59
Tourette syndrome 0.8 0.4 1
Type 1 Diabetes 4.3 5.2 -0.21
Type 2 Diabetes 10.6 8.5 0.25
Ulcerative colitis 6.1 8.6 -0.41
Unhealthy Ageing 6 2.9 1.07
Vitiligo 3.3 1.5 1.2

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