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🍽️ cinoxacin (antibiotic)

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  1. Urinary Tract Infections (UTIs): Cinoxacin is effective against a wide range of bacteria commonly implicated in urinary tract infections, including Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Enterobacter species. It is often prescribed for uncomplicated UTIs, such as cystitis and pyelonephritis, where it can help alleviate symptoms and eradicate the infection.

  2. Prostatitis: Cinoxacin may also be used in the treatment of bacterial prostatitis, an inflammation of the prostate gland usually caused by bacterial infection. It can penetrate prostatic tissues and achieve therapeutic concentrations in the prostate, making it effective against causative pathogens.

  3. Gastrointestinal Infections: In some cases, cinoxacin may be prescribed for gastrointestinal infections caused by susceptible bacteria. This includes infectious diarrhea caused by certain strains of bacteria such as Shigella and Salmonella.

  4. Respiratory Tract Infections: Cinoxacin is not typically used as a first-line treatment for respiratory tract infections. However, in some cases where the causative bacteria are known to be susceptible to cinoxacin, it may be considered for the treatment of respiratory infections such as bronchitis or pneumonia.

  5. Skin and Soft Tissue Infections: Cinoxacin is not commonly used to treat skin and soft tissue infections. Other antibiotics are usually preferred for these types of infections, as they may be more effective and have a lower risk of developing bacterial resistance.

  6. Side Effects: Like all antibiotics, cinoxacin can cause side effects. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and skin rash. Rare but serious side effects may include tendon rupture, particularly in older adults, and central nervous system effects such as seizures or hallucinations.

  7. Drug Interactions: Cinoxacin may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting cinoxacin therapy.

  8. Pregnancy and Lactation: The safety of cinoxacin use during pregnancy and lactation has not been well established. It is generally not recommended for use in pregnant or breastfeeding women unless the potential benefits outweigh the risks.

  9. Bacterial Resistance: Like other antibiotics, the overuse or misuse of cinoxacin can contribute to the development of bacterial resistance, reducing its effectiveness in treating infections. It is important to use cinoxacin judiciously and only when necessary to help preserve its efficacy.

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Check for interactions on Supp.AI   |   📚 PubMed Citations

⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of cinoxacin (antibiotic) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by cinoxacin (antibiotic)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Parabacteroides genus Decreases
0 1 Escherichia genus Decreases
0 1 Clostridium genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Shigella genus Decreases
0 1 Clostridioides genus Decreases
0 1 Agathobacter genus Decreases
0 1 Bacteroides genus Decreases
0 1 Eggerthella genus Decreases
0 1 Roseburia genus Decreases
0 1 Coprococcus genus Decreases
0 1 Streptococcus genus Decreases
0 1 Bilophila genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Dorea genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Veillonella genus Decreases
0 1 Blautia genus Decreases
1 0 Akkermansia genus Decreases
0 1 Segatella genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Clostridium perfringens species Decreases
1 0 Escherichia coli species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Agathobacter rectalis species Decreases
0 1 Shigella dysenteriae species Decreases
1 0 Eggerthella lenta species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Escherichia fergusonii species Decreases
1 0 Coprococcus comes species Decreases
0 1 Shigella boydii species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Bacteroides sp. A1C1 species Decreases
0 1 Shigella sonnei species Decreases
1 0 Bilophila wadsworthia species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Bacteroides sp. HF-162 species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Parabacteroides johnsonii species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Hungatella hathewayi species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Veillonella parvula species Decreases
1 0 Blautia obeum species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Roseburia hominis species Decreases
1 0 Segatella copri species Decreases
1 0 Bacteroides caccae species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases

Impact of cinoxacin (antibiotic) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 0.2
Acne 0.1 -0.1
ADHD 2 0.3 5.67
Age-Related Macular Degeneration and Glaucoma 0.2 0.5 -1.5
Allergic Rhinitis (Hay Fever) 2 1.1 0.82
Allergies 4.4 1.1 3
Allergy to milk products 1.4 1.2 0.17
Alopecia (Hair Loss) 0.2 0.2
Alzheimer's disease 4.4 3.8 0.16
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.7 0.6 1.83
Ankylosing spondylitis 1.9 0.6 2.17
Anorexia Nervosa 1.2 1.7 -0.42
Antiphospholipid syndrome (APS) 1.3 0.1 12
Asthma 3 0.6 4
Atherosclerosis 1.7 1.1 0.55
Atrial fibrillation 1.8 2 -0.11
Autism 5.8 5.3 0.09
Autoimmune Disease 1 0.7 0.43
Barrett esophagus cancer 0.4 0.1 3
benign prostatic hyperplasia 0.8 0.2 3
Biofilm 1.7 1.7
Bipolar Disorder 2.2 0.4 4.5
Brain Trauma 0.2 0.3 -0.5
Breast Cancer 1.3 1.3
Cancer (General) 0.4 0.8 -1
Carcinoma 2.6 0.8 2.25
Celiac Disease 2.6 1 1.6
Cerebral Palsy 0.9 0.3 2
Chronic Fatigue Syndrome 2.9 2.6 0.12
Chronic Kidney Disease 2.4 0.7 2.43
Chronic Lyme 0.6 0.3 1
Chronic Obstructive Pulmonary Disease (COPD) 1.4 0.7 1
Chronic Urticaria (Hives) 1.7 0.7 1.43
Coagulation / Micro clot triggering bacteria 2 0.3 5.67
Cognitive Function 0.9 0.8 0.13
Colorectal Cancer 6.2 2 2.1
Constipation 1.6 0.2 7
Coronary artery disease 1.8 1.4 0.29
COVID-19 5.9 3.6 0.64
Crohn's Disease 6.5 2.4 1.71
Cushing's Syndrome (hypercortisolism) 0.8 -0.8
cystic fibrosis 1.1 0.4 1.75
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 2.8 0.4 6
Denture Wearers Oral Shifts 0.8 0.8
Depression 6.2 4.6 0.35
Dermatomyositis 0.1 0.1 0
Eczema 1.9 1.2 0.58
Endometriosis 2.4 0.9 1.67
Eosinophilic Esophagitis 0.3 0.1 2
Epilepsy 3.3 1.4 1.36
erectile dysfunction 1.8 0.1 17
Fibromyalgia 2.2 1.5 0.47
Functional constipation / chronic idiopathic constipation 4.6 2.2 1.09
gallstone disease (gsd) 2.9 0.5 4.8
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 2.2 0.2 10
Generalized anxiety disorder 2.5 1.1 1.27
giant cell arteritis 0.5 -0.5
Glioblastoma 0.1 -0.1
Gout 0.3 1 -2.33
Graves' disease 0.7 0.6 0.17
Gulf War Syndrome 0.7 0.8 -0.14
Halitosis 1.3 0.1 12
Hashimoto's thyroiditis 1.4 0.3 3.67
Heart Failure 4.1 0.6 5.83
hemorrhagic stroke 0.9 0.9
Hidradenitis Suppurativa 0.7 0 0
High Histamine/low DAO 1.8 0.1 17
hypercholesterolemia (High Cholesterol) 1.1 0 0
hyperglycemia 1.5 0.8 0.88
Hyperlipidemia (High Blood Fats) 0.1 0.1
hypersomnia 0.1 -0.1
hypertension (High Blood Pressure 2.4 1.5 0.6
Hypothyroidism 0 0.3 0
Hypoxia 1.9 1.9
IgA nephropathy (IgAN) 1.2 1.6 -0.33
Inflammatory Bowel Disease 7.3 4.1 0.78
Insomnia 0.5 0.7 -0.4
Intelligence 1.9 0 0
Intracranial aneurysms 1 0.2 4
Irritable Bowel Syndrome 4.1 2.8 0.46
ischemic stroke 1.6 1.3 0.23
Liver Cirrhosis 4.2 2.2 0.91
Long COVID 3.4 1.9 0.79
Low bone mineral density 0.2 -0.2
Lung Cancer 0.9 0.1 8
Lymphoma 0.8 0.8
Mast Cell Issues / mastitis 1.6 0.2 7
ME/CFS with IBS 0.6 0.6 0
ME/CFS without IBS 1.2 0.4 2
membranous nephropathy 0.1 0.1
Menopause 0.2 0.2 0
Metabolic Syndrome 4.5 4.1 0.1
Mood Disorders 5.6 4.1 0.37
multiple chemical sensitivity [MCS] 0.2 0 0
Multiple Sclerosis 4.6 3.3 0.39
Multiple system atrophy (MSA) 0.3 0.1 2
myasthenia gravis 0.9 0.6 0.5
neuropathic pain 0.1 0.9 -8
Neuropathy (all types) 0.3 1.1 -2.67
neuropsychiatric disorders (PANDAS, PANS) 0.7 0.7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.9 1.1 1.64
NonCeliac Gluten Sensitivity 0.4 0.2 1
Obesity 3.9 3.6 0.08
obsessive-compulsive disorder 4.3 0.9 3.78
Osteoarthritis 2.1 0.3 6
Osteoporosis 1.8 0.4 3.5
pancreatic cancer 0.8 0.1 7
Parkinson's Disease 4.5 3.8 0.18
Polycystic ovary syndrome 4.7 1.1 3.27
Postural orthostatic tachycardia syndrome 0.5 0.2 1.5
Premenstrual dysphoric disorder 0.1 0.5 -4
primary biliary cholangitis 0.2 1.5 -6.5
Primary sclerosing cholangitis 1.9 1.3 0.46
Psoriasis 2 1.4 0.43
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.2 2.3 0.39
Rosacea 0.1 0.6 -5
Schizophrenia 3.4 1.5 1.27
scoliosis 0.7 0.1 6
Sjögren syndrome 1.6 1.5 0.07
Sleep Apnea 0.9 0.6 0.5
Slow gastric motility / Gastroparesis 0.8 0.1 7
Small Intestinal Bacterial Overgrowth (SIBO) 1.8 0.1 17
Stress / posttraumatic stress disorder 2.7 1.3 1.08
Systemic Lupus Erythematosus 3.5 0.2 16.5
Tic Disorder 0.7 0.1 6
Tourette syndrome 0.2 0.2 0
Type 1 Diabetes 3.1 1.7 0.82
Type 2 Diabetes 5.1 4.6 0.11
Ulcerative colitis 5.4 4.1 0.32
Unhealthy Ageing 3.6 1.2 2
Vitiligo 1.4 1.3 0.08

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