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🍽️ saquinavir mesylate,(prescription)

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  1. Antiretroviral Therapy (ART): Saquinavir mesylate is used as part of combination antiretroviral therapy (ART) regimens for the treatment of HIV infection. It helps control the progression of the disease by suppressing viral replication and improving immune function.

  2. HIV/AIDS Treatment: Saquinavir mesylate is effective in reducing HIV viral load and increasing CD4 cell counts, which are key markers of HIV disease progression. By lowering viral load and boosting immune function, it helps delay the onset of AIDS-related complications and improves the quality of life for HIV-infected individuals.

  3. Drug Resistance: Like other antiretroviral drugs, saquinavir mesylate can contribute to the development of drug-resistant strains of HIV if not used properly or in combination with other medications. Therefore, it is essential to adhere to prescribed dosing schedules and combination therapy regimens to minimize the risk of drug resistance.

  4. Side Effects: Common side effects of saquinavir mesylate may include nausea, diarrhea, abdominal discomfort, headache, fatigue, and changes in liver enzyme levels. These side effects are usually mild to moderate in severity and may diminish over time as the body adjusts to the medication.

  5. Metabolic Effects: Saquinavir mesylate may also affect lipid metabolism, leading to elevated levels of cholesterol and triglycerides in some individuals. This can increase the risk of cardiovascular disease and may require monitoring and management with lipid-lowering medications or lifestyle modifications.

  6. Drug Interactions: Saquinavir mesylate can interact with other medications, including other antiretroviral drugs, to alter their metabolism and efficacy. It may also interact with certain herbal supplements and over-the-counter medications. Patients should inform their healthcare providers about all medications they are taking to avoid potential drug interactions.

  7. Hepatotoxicity: In rare cases, saquinavir mesylate may cause hepatotoxicity (liver damage), characterized by elevated liver enzyme levels, jaundice, and hepatic dysfunction. Liver function tests should be monitored regularly during treatment, and the medication may need to be discontinued if signs of liver toxicity occur.

  8. Pregnancy and Breastfeeding: The safety of saquinavir mesylate during pregnancy and breastfeeding is not well established. Pregnant women and breastfeeding mothers should discuss the potential risks and benefits of treatment with their healthcare providers.

  9. Special Populations: Saquinavir mesylate should be used with caution in patients with pre-existing liver disease, as well as those with certain cardiovascular conditions, due to its potential effects on lipid metabolism and cardiovascular risk factors.

  10. Resistance Testing: Resistance testing may be performed prior to initiating saquinavir mesylate therapy to assess the susceptibility of the virus to the medication and guide treatment decisions.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of saquinavir mesylate,(prescription) On Probiotics

Rank Probiotic Impact
species Bacteroides uniformis Reduces
species Escherichia coli Reduces
species Parabacteroides distasonis Reduces

Bacteria Impacted by saquinavir mesylate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Escherichia genus Decreases
0 1 Dorea genus Decreases
0 1 Roseburia genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Agathobacter genus Decreases
0 1 Bacteroides genus Decreases
0 1 Bilophila genus Decreases
0 1 Coprococcus genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Odoribacter genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Streptococcus genus Decreases
0 1 Segatella genus Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Coprococcus comes species Decreases
1 0 Escherichia coli species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia hominis species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Segatella copri species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Bacteroides xylanisolvens species Decreases

Impact of saquinavir mesylate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.9 0.9
Acne 0.6 0.6
ADHD 2.4 0.3 7
Age-Related Macular Degeneration and Glaucoma 1.1 0.4 1.75
Allergic Rhinitis (Hay Fever) 2.9 0.9 2.22
Allergies 3.1 0.9 2.44
Allergy to milk products 1.2 1.3 -0.08
Alopecia (Hair Loss) 0.7 0.7
Alzheimer's disease 3.7 5.9 -0.59
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.3 0.6 2.83
Ankylosing spondylitis 3.1 1 2.1
Anorexia Nervosa 0.7 2.3 -2.29
Antiphospholipid syndrome (APS) 2.1 0.3 6
Asthma 3.8 1.1 2.45
Atherosclerosis 1.5 2.3 -0.53
Atrial fibrillation 2.7 2.8 -0.04
Autism 5.8 6.7 -0.16
Autoimmune Disease 0.9 0.5 0.8
Barrett esophagus cancer 0.3 -0.3
benign prostatic hyperplasia 0.6 0.3 1
Biofilm 1.6 1.6
Bipolar Disorder 1.6 0.8 1
Brain Trauma 0.3 0.8 -1.67
Breast Cancer 0.6 0.6
Cancer (General) 0.3 0.3 0
Carcinoma 2.8 1.6 0.75
Celiac Disease 3.3 1.9 0.74
Cerebral Palsy 0.6 0.8 -0.33
Chronic Fatigue Syndrome 2.5 5.4 -1.16
Chronic Kidney Disease 2.9 1.7 0.71
Chronic Lyme 0.8 -0.8
Chronic Obstructive Pulmonary Disease (COPD) 1.8 1.1 0.64
Chronic Urticaria (Hives) 1.5 1.2 0.25
Coagulation / Micro clot triggering bacteria 1.9 0.8 1.37
Cognitive Function 2.1 1.1 0.91
Colorectal Cancer 5.5 2 1.75
Constipation 1.5 0.5 2
Coronary artery disease 2.5 2.6 -0.04
COVID-19 5.1 8.3 -0.63
Crohn's Disease 6.8 3.6 0.89
Cushing's Syndrome (hypercortisolism) 0.9 -0.9
cystic fibrosis 1.2 0.8 0.5
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 2.6 1.1 1.36
Denture Wearers Oral Shifts 0.9 0.9
Depression 6.5 6.3 0.03
Dermatomyositis 0.3 0.3
Eczema 1.6 1.5 0.07
Endometriosis 3.1 1.7 0.82
Eosinophilic Esophagitis 0.3 -0.3
Epilepsy 2.4 1.3 0.85
erectile dysfunction 1.6 1.6
Fibromyalgia 2.2 2.1 0.05
Functional constipation / chronic idiopathic constipation 4.6 3.1 0.48
gallstone disease (gsd) 3.5 0.5 6
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.2 0.3 3
Generalized anxiety disorder 2.7 0.9 2
Glioblastoma 0.3 -0.3
Gout 0.9 0.3 2
Graves' disease 0.7 2 -1.86
Gulf War Syndrome 0.6 1.2 -1
Halitosis 0.6 0.3 1
Hashimoto's thyroiditis 2 0.6 2.33
Heart Failure 3.2 1.1 1.91
hemorrhagic stroke 1 1
Hidradenitis Suppurativa 0.9 0.9
High Histamine/low DAO 1.1 1.1
hypercholesterolemia (High Cholesterol) 0.9 0.9
hyperglycemia 1.8 0.7 1.57
Hyperlipidemia (High Blood Fats) 0.3 0.3
hypersomnia 0.3 -0.3
hypertension (High Blood Pressure 2.8 3.8 -0.36
Hypothyroidism 0.3 -0.3
Hypoxia 2.5 0.6 3.17
IgA nephropathy (IgAN) 1 3 -2
Inflammatory Bowel Disease 5.3 5.7 -0.08
Insomnia 2.1 1.4 0.5
Intelligence 1.8 0.6 2
Intracranial aneurysms 0.7 0.3 1.33
Irritable Bowel Syndrome 5.1 3 0.7
ischemic stroke 1.6 1.7 -0.06
Liver Cirrhosis 6.3 2.9 1.17
Long COVID 5 3.6 0.39
Low bone mineral density 0.8 -0.8
Lung Cancer 1.2 0.6 1
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 0.9 0.3 2
ME/CFS with IBS 0.3 1.1 -2.67
ME/CFS without IBS 1 1.2 -0.2
membranous nephropathy 0.3 0.3
Menopause 0.3 0.5 -0.67
Metabolic Syndrome 6.4 5.4 0.19
Mood Disorders 4.7 4.5 0.04
multiple chemical sensitivity [MCS] 0.9 0.9
Multiple Sclerosis 3.4 4 -0.18
Multiple system atrophy (MSA) 0.7 0.7
myasthenia gravis 0.9 0.5 0.8
neuropathic pain 2.5 -2.5
Neuropathy (all types) 0.3 2.2 -6.33
neuropsychiatric disorders (PANDAS, PANS) 1.2 1.2
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.8 2 0.9
NonCeliac Gluten Sensitivity 0.3 0.3 0
Obesity 7.2 4.6 0.57
obsessive-compulsive disorder 4 3.3 0.21
Osteoarthritis 2.5 0.6 3.17
Osteoporosis 1.4 1.2 0.17
pancreatic cancer 0.6 0.3 1
Parkinson's Disease 4.8 5.3 -0.1
Polycystic ovary syndrome 5.1 1.7 2
Postural orthostatic tachycardia syndrome 0.3 -0.3
Premenstrual dysphoric disorder 0.4 -0.4
primary biliary cholangitis 0.9 0.9 0
Primary sclerosing cholangitis 1.1 1.6 -0.45
Psoriasis 1.6 2.9 -0.81
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 4.8 3.2 0.5
Rosacea 0.5 -0.5
Schizophrenia 2.5 1.6 0.56
scoliosis 0.9 0.3 2
Sjögren syndrome 2.2 2.2 0
Sleep Apnea 0.9 1.1 -0.22
Slow gastric motility / Gastroparesis 0.9 0.9
Small Intestinal Bacterial Overgrowth (SIBO) 1.5 1.5
Stress / posttraumatic stress disorder 2.4 1.6 0.5
Systemic Lupus Erythematosus 3.7 0.8 3.63
Tic Disorder 1.2 1.2 0
Tourette syndrome 0.9 0.3 2
Type 1 Diabetes 2.9 1.7 0.71
Type 2 Diabetes 7 5.4 0.3
Ulcerative colitis 4 5.7 -0.43
Unhealthy Ageing 3.6 2.2 0.64
Vitiligo 1.6 1 0.6

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