🍽️ cinnarizine,(prescription)

Motion Sickness: Cinnarizine is effective in preventing and relieving symptoms of motion sickness, including nausea, vomiting, dizziness, and vertigo, commonly experienced during travel by car, boat, or airplane. It works by blocking histamine H1 receptors in the vestibular system and the vomiting center of the brain, thereby reducing the sensitivity of the inner ear to motion stimuli and decreasing the likelihood of motion sickness symptoms.

Vertigo: Cinnarizine is also used to treat vertigo, a sensation of spinning or dizziness often associated with inner ear disorders such as benign paroxysmal positional vertigo (BPPV), vestibular neuritis, and Meniere's disease. By exerting its antihistamine and calcium channel blocking effects, cinnarizine helps alleviate vertigo symptoms and improve balance and stability in affected individuals.

Peripheral Vestibular Disorders: Cinnarizine may be prescribed for individuals with peripheral vestibular disorders characterized by disturbances in balance and spatial orientation, such as labyrinthitis, vestibular neuronitis, and vestibular migraine. It can help reduce vertigo attacks and associated symptoms, allowing patients to better cope with their condition and maintain daily activities.

Inner Ear Disorders: Cinnarizine is sometimes used off-label in the treatment of various inner ear disorders, including tinnitus (ringing in the ears) and hearing loss associated with vestibular dysfunction. Although its efficacy in these conditions is less well-established, cinnarizine may provide symptomatic relief by modulating blood flow and reducing the hyperexcitability of the vestibular system.

Ménière's Disease: Cinnarizine may be prescribed as part of the management plan for individuals with Ménière's disease, a chronic inner ear disorder characterized by recurrent episodes of vertigo, sensorineural hearing loss, tinnitus, and a sensation of fullness or pressure in the affected ear. Cinnarizine can help alleviate vertigo attacks and associated symptoms, although its long-term efficacy in preventing disease progression is uncertain.

Side Effects: Common side effects of cinnarizine may include drowsiness, dry mouth, blurred vision, constipation, and gastrointestinal disturbances. These side effects are usually mild and transient, and they may diminish with continued use or dose adjustment. Cinnarizine may cause drowsiness or impair alertness, so individuals should avoid activities that require mental alertness or coordination, such as driving or operating heavy machinery, until they know how the medication affects them.

Contraindications: Cinnarizine is contraindicated in individuals with a known hypersensitivity to the medication or any of its components, as well as those with Parkinson's disease, hypotension, severe heart failure, or severe hepatic impairment. It should be used with caution in elderly patients and those with glaucoma, urinary retention, or prostatic hypertrophy.