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🍽️ clavulanate potassium salt (antibiotic)

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  1. Gastrointestinal Effects: Like many antibiotics, amoxicillin/clavulanate potassium can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal pain. These symptoms are usually mild and temporary but can sometimes be severe.

  2. Allergic Reactions: Some individuals may experience allergic reactions to amoxicillin/clavulanate potassium, which can manifest as rash, itching, swelling, or difficulty breathing. Severe allergic reactions like anaphylaxis are rare but can occur.

  3. Clostridium difficile Infection: The use of amoxicillin/clavulanate potassium, like other antibiotics, can disrupt the normal balance of bacteria in the gut, leading to the overgrowth of Clostridium difficile bacteria and causing a potentially severe infection known as C. difficile-associated diarrhea.

  4. Liver Problems: Rarely, amoxicillin/clavulanate potassium can cause liver toxicity, leading to elevated liver enzymes or liver damage. Symptoms may include jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.

  5. Drug Interactions: Amoxicillin/clavulanate potassium can interact with other medications, including certain anticoagulants, oral contraceptives, and medications used to treat gout. These interactions can lead to altered drug levels in the body and potentially serious side effects.

  6. Skin Reactions: Some individuals may develop skin reactions like rash, hives, or photosensitivity (increased sensitivity to sunlight) while taking amoxicillin/clavulanate potassium.

  7. Respiratory Effects: Amoxicillin/clavulanate potassium may rarely cause respiratory side effects such as cough or shortness of breath.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of clavulanate potassium salt (antibiotic) On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Lactococcus cremoris Reduces
species Lactococcus lactis Reduces

Bacteria Impacted by clavulanate potassium salt (antibiotic)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Odoribacter genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Blautia genus Decreases
1 0 Akkermansia genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Segatella genus Decreases
0 1 Dorea genus Decreases
0 1 Coprococcus genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Roseburia genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Wansuia genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Coprobacter genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Massilistercora genus Decreases
0 1 Treponema genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Christensenella genus Decreases
0 1 Eubacterium genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Qiania genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Wujia genus Decreases
0 1 Marvinbryantia genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Olsenella genus Decreases
0 1 Longicatena genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Anaerostipes genus Decreases
0 1 Faecalibacillus genus Decreases
0 1 Mageeibacillus genus Decreases
0 1 Monoglobus genus Decreases
0 1 Adlercreutzia genus Decreases
0 1 Lactococcus genus Decreases
0 1 Leyella genus Decreases
0 1 Vescimonas genus Decreases
0 1 Oscillibacter genus Decreases
0 1 Fannyhessea genus Decreases
0 1 Bilophila genus Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Blautia obeum species Decreases
1 0 Coprococcus comes species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Segatella copri species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Roseburia intestinalis species Decreases
0 1 Dorea longicatena species Decreases
0 1 Coprococcus catus species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Segatella bryantii species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 [Ruminococcus] torques species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Blautia liquoris species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Streptococcus suis species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Christensenella minuta species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Treponema peruense species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Actinomyces oris species Decreases
0 1 Parvimonas micra species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Blautia argi species Decreases
0 1 Roseburia hominis species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Leyella stercorea species Decreases
0 1 Coprobacter secundus species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Treponema denticola species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Barnesiella viscericola species Decreases
0 1 Wujia chipingensis species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Alistipes megaguti species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Emergencia timonensis species Decreases
0 1 Prevotella intermedia species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Coprobacter fastidiosus species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Leyella lascolaii species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Alistipes ihumii species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Butyricimonas faecalis species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Romboutsia ilealis species Decreases
0 1 Alistipes dispar species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Paraprevotella clara species Decreases
0 1 Prevotella bivia species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Parabacteroides merdae species Decreases
0 1 [Clostridium] scindens species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Clostridioides difficile species Decreases
0 1 Alistipes communis species Decreases
0 1 Bacteroides nordii species Decreases
0 1 Bacteroides intestinalis species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Blautia pseudococcoides species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Alistipes senegalensis species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Lachnospira eligens species Decreases
0 1 Lactococcus lactis species Decreases
0 1 Prevotella dentalis species Decreases
1 0 Bilophila wadsworthia species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of clavulanate potassium salt (antibiotic) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.2 0.2
ADHD 1.6 1 0.6
Age-Related Macular Degeneration and Glaucoma 0.8 0.8
Allergic Rhinitis (Hay Fever) 1.6 0.7 1.29
Allergies 3.8 3.5 0.09
Allergy to milk products 1.8 0.3 5
Alopecia (Hair Loss) 1.2 0.1 11
Alzheimer's disease 5.3 3.5 0.51
Amyotrophic lateral sclerosis (ALS) Motor Neuron 2.9 1.3 1.23
Ankylosing spondylitis 2.3 1.4 0.64
Anorexia Nervosa 1 1.9 -0.9
Antiphospholipid syndrome (APS) 0.4 0 0
Asthma 2.1 1.4 0.5
Atherosclerosis 1.4 1.8 -0.29
Atrial fibrillation 1.9 0.9 1.11
Autism 6 5.2 0.15
Autoimmune Disease 0.2 -0.2
Barrett esophagus cancer 0.4 0.4
Biofilm 1.2 1.2
Bipolar Disorder 0.6 1.1 -0.83
Brain Trauma 0.3 0.8 -1.67
Breast Cancer 0.6 0.6
Cancer (General) 0.9 0.2 3.5
Carcinoma 3.7 2.5 0.48
Celiac Disease 1 2.7 -1.7
Cerebral Palsy 0.6 1.3 -1.17
Chronic Fatigue Syndrome 2.8 5 -0.79
Chronic Kidney Disease 1.6 1.9 -0.19
Chronic Lyme 0.1 0.2 -1
Chronic Obstructive Pulmonary Disease (COPD) 0.9 1.3 -0.44
Chronic Urticaria (Hives) 1.2 -1.2
Coagulation / Micro clot triggering bacteria 0.1 1.8 -17
Cognitive Function 1.1 0.9 0.22
Colorectal Cancer 4.3 0.5 7.6
Constipation 0.5 0.7 -0.4
Coronary artery disease 1.4 2.4 -0.71
COVID-19 4.7 9.2 -0.96
Crohn's Disease 5.5 5.7 -0.04
cystic fibrosis 0.7 -0.7
d-lactic acidosis (one form of brain fog) 0.1 0.1
deep vein thrombosis 1.8 1.3 0.38
Denture Wearers Oral Shifts 0.9 0.9
Depression 4.8 5.6 -0.17
Eczema 0.8 0.1 7
Endometriosis 1.7 1.6 0.06
Eosinophilic Esophagitis 0.4 0.4
Epilepsy 1.8 1.8 0
erectile dysfunction 0.5 0.1 4
Fibromyalgia 1.3 1.4 -0.08
Functional constipation / chronic idiopathic constipation 2.2 2.9 -0.32
gallstone disease (gsd) 2 1.2 0.67
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.1 1.3 -0.18
Generalized anxiety disorder 2.3 1 1.3
Glioblastoma 0.1 0.1 0
Gout 1 0.9 0.11
Graves' disease 0.5 1.8 -2.6
Gulf War Syndrome 0.9 1.1 -0.22
Halitosis 1.3 1.3
Hashimoto's thyroiditis 3.2 0.9 2.56
Heart Failure 2.6 2.4 0.08
hemorrhagic stroke 1 1
Hidradenitis Suppurativa 0.4 0.4
High Histamine/low DAO 0.2 0.5 -1.5
hypercholesterolemia (High Cholesterol) 0.5 0.7 -0.4
hyperglycemia 0.4 1.6 -3
Hyperlipidemia (High Blood Fats) 0.7 0.7
hypersomnia 0.6 -0.6
hypertension (High Blood Pressure 3.5 3.8 -0.09
Hypothyroidism 0.8 1.3 -0.63
Hypoxia 1 1
IgA nephropathy (IgAN) 1.2 1.7 -0.42
Inflammatory Bowel Disease 3.1 7 -1.26
Insomnia 1.8 2.5 -0.39
Intelligence 0.4 1 -1.5
Intracranial aneurysms 1.5 0.5 2
Irritable Bowel Syndrome 4.5 2.8 0.61
ischemic stroke 1 0.3 2.33
Juvenile idiopathic arthritis 0.1 0.1 0
Liver Cirrhosis 4.4 4.1 0.07
Long COVID 4.2 6.3 -0.5
Low bone mineral density 0.1 1.1 -10
Lung Cancer 0 2.3 0
Lymphoma 0.1 -0.1
Mast Cell Issues / mastitis 0.6 0.9 -0.5
ME/CFS with IBS 2.7 -2.7
ME/CFS without IBS 0.8 1.3 -0.63
Menopause 0.2 0.8 -3
Metabolic Syndrome 5.3 5.6 -0.06
Mood Disorders 5.1 3.8 0.34
multiple chemical sensitivity [MCS] 0.5 0.5 0
Multiple Sclerosis 3.1 3.4 -0.1
Multiple system atrophy (MSA) 1.2 1 0.2
myasthenia gravis 0.3 -0.3
neuropathic pain 1.4 -1.4
Neuropathy (all types) 1.1 0.8 0.38
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.6 4.5 -0.25
NonCeliac Gluten Sensitivity 1.1 1.1
Obesity 8.3 6.8 0.22
obsessive-compulsive disorder 1.8 3.8 -1.11
Osteoarthritis 1.4 1.3 0.08
Osteoporosis 0.7 1.8 -1.57
pancreatic cancer 1.1 1.1
Parkinson's Disease 5.4 4.8 0.13
Polycystic ovary syndrome 4 2.8 0.43
Postural orthostatic tachycardia syndrome 0.5 -0.5
Premenstrual dysphoric disorder 0.5 0.5
primary biliary cholangitis 0.5 0.4 0.25
Primary sclerosing cholangitis 0.6 3 -4
Psoriasis 2.1 2 0.05
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 6 2.8 1.14
Rosacea 0.7 0.2 2.5
Schizophrenia 3.5 2.4 0.46
scoliosis 0.8 0.6 0.33
sensorineural hearing loss 0.5 0.5
Sjögren syndrome 1.7 1 0.7
Sleep Apnea 2.5 1.2 1.08
Slow gastric motility / Gastroparesis 0.6 0.6
Small Intestinal Bacterial Overgrowth (SIBO) 1.1 1.1
Stress / posttraumatic stress disorder 1.7 1.3 0.31
Systemic Lupus Erythematosus 2.3 2.1 0.1
Tic Disorder 1 1.7 -0.7
Tourette syndrome 0.9 0.9
Type 1 Diabetes 2.3 1.1 1.09
Type 2 Diabetes 5.3 4.3 0.23
Ulcerative colitis 2.6 4.5 -0.73
Unhealthy Ageing 2.6 2 0.3
Vitiligo 0.7 1.4 -1

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