AI Engines For more Details: Perplexity Kagi Labs You
Anticancer Effects: Gemcitabine is effective in treating several types of cancer, including pancreatic cancer, lung cancer, breast cancer, ovarian cancer, and bladder cancer. It works by interfering with the growth and spread of cancer cells in the body.
Cell Cycle Arrest: Gemcitabine disrupts the cell cycle of cancer cells, leading to cell cycle arrest and inhibition of DNA synthesis. This prevents cancer cells from dividing and multiplying.
Apoptosis Induction: Gemcitabine induces apoptosis, or programmed cell death, in cancer cells. By triggering apoptosis, it helps to eliminate cancer cells from the body.
Combination Therapy: Gemcitabine is often used in combination with other chemotherapy drugs or treatments to enhance its effectiveness. Combinations may vary depending on the type and stage of cancer being treated.
Adverse Effects: Common side effects of gemcitabine treatment include nausea, vomiting, diarrhea, fatigue, hair loss (alopecia), mouth sores, decreased appetite, and flu-like symptoms such as fever and chills. These side effects are usually temporary and can often be managed with supportive care.
Bone Marrow Suppression: Gemcitabine can suppress the bone marrow's ability to produce blood cells, leading to decreased levels of white blood cells, red blood cells, and platelets. This can increase the risk of infections, anemia, and bleeding tendencies.
Peripheral Neuropathy: Some individuals may experience peripheral neuropathy, characterized by numbness, tingling, or burning sensations in the hands and feet. This side effect is usually reversible but can persist after treatment cessation in some cases.
Liver and Kidney Function: Gemcitabine may affect liver and kidney function, and periodic monitoring of liver enzymes and kidney function tests may be necessary during treatment.
Infusion Reactions: Rarely, gemcitabine infusion may cause allergic or infusion-related reactions, including fever, chills, rash, and difficulty breathing. These reactions typically occur during or shortly after infusion and require immediate medical attention.
Long-Term Side Effects: Some individuals may experience long-term side effects of gemcitabine treatment, such as secondary cancers, fertility issues, and cognitive changes. These risks should be discussed with a healthcare provider before starting treatment.
Contraindications: Gemcitabine is contraindicated in individuals with a history of severe allergic reactions to the medication or its components. It should be used with caution in individuals with impaired kidney or liver function.
Monitoring: Regular monitoring of blood counts, liver function tests, and kidney function tests is essential during gemcitabine treatment to assess its efficacy and detect any potential adverse effects.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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