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🍽️ norcyclobenzaprine,(prescription)

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  1. Muscle Relaxation: Cyclobenzaprine and its metabolite, norcyclobenzaprine, primarily work by inhibiting muscle spasms and promoting muscle relaxation. This can help alleviate muscle stiffness, tension, and pain associated with conditions such as muscle strains, sprains, or musculoskeletal injuries.

  2. Pain Relief: By reducing muscle spasms and tension, cyclobenzaprine and norcyclobenzaprine may indirectly alleviate pain associated with muscle-related conditions.

  3. Fibromyalgia: Cyclobenzaprine is sometimes used off-label to manage symptoms of fibromyalgia, a chronic condition characterized by widespread musculoskeletal pain, fatigue, and tenderness in specific areas of the body. The muscle-relaxing properties of cyclobenzaprine may help reduce pain and improve sleep quality in some individuals with fibromyalgia.

  4. Central Nervous System Depression: Cyclobenzaprine and its metabolite may cause sedation and drowsiness, which can impair cognitive and motor function. Therefore, it's essential to use caution when operating machinery or engaging in activities that require alertness until the effects of the medication are known.

  5. Adverse Effects: Common side effects associated with cyclobenzaprine therapy, which may also occur with norcyclobenzaprine use, include drowsiness, dizziness, dry mouth, blurred vision, and constipation. Less common but potentially serious side effects include cardiac arrhythmias, serotonin syndrome (when used in combination with other serotonergic drugs), and anticholinergic effects.

  6. Drug Interactions: Cyclobenzaprine and its metabolite may interact with other medications, such as monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and certain opioids, potentially leading to adverse effects or reduced efficacy.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of norcyclobenzaprine,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium bifidum Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium catenulatum Reduces
species Bifidobacterium longum Reduces
species Blautia hansenii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Escherichia coli Reduces
species Faecalibacterium prausnitzii Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Parabacteroides distasonis Reduces
species Veillonella atypica Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by norcyclobenzaprine,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Lachnospira genus Decreases
1 0 Akkermansia genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Eggerthella genus Decreases
0 1 Agathobacter genus Decreases
0 1 Roseburia genus Decreases
0 1 Veillonella genus Decreases
0 1 Enterocloster genus Decreases
0 1 Collinsella genus Decreases
0 1 Blautia genus Decreases
0 1 Clostridium genus Decreases
0 1 Odoribacter genus Decreases
0 1 Segatella genus Decreases
0 1 Bacteroides genus Decreases
0 1 Dorea genus Decreases
0 1 Clostridioides genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Thomasclavelia genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Coprococcus genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Parolsenella genus Decreases
0 1 Flavonifractor genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Wansuia genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Coprobacter genus Decreases
0 1 Escherichia genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Akkermansia muciniphila species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Blautia obeum species Decreases
1 0 Clostridium perfringens species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Lacrimispora saccharolytica species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia hominis species Decreases
1 0 Segatella copri species Decreases
1 0 Veillonella parvula species Decreases
1 0 Thomasclavelia ramosa species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Coprococcus comes species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Ruminococcus bromii species Decreases
0 1 Veillonella rodentium species Decreases
0 1 Veillonella dispar species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Segatella bryantii species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Coprococcus catus species Decreases
1 0 Parabacteroides merdae species Decreases
0 1 Veillonella nakazawae species Decreases
0 1 Dorea longicatena species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Blautia parvula species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Veillonella rogosae species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Parolsenella catena species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Bacteroides sp. A1C1 species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Flavonifractor plautii species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Blautia liquoris species Decreases
0 1 Bacteroides sp. HF-162 species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Leyella stercorea species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Christensenella minuta species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Veillonella atypica species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Bacteroides sp. D2 species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Alistipes megaguti species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Hungatella hathewayi species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Prevotella intermedia species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Bacteroides sp. M10 species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Coprobacter fastidiosus species Decreases
1 0 Escherichia coli species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Roseburia intestinalis species Decreases
0 1 Treponema peruense species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Streptococcus suis species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Leyella lascolaii species Decreases
0 1 Enterocloster clostridioformis species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Blautia argi species Decreases
0 1 Alistipes finegoldii species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Barnesiella viscericola species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Alistipes onderdonkii species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Actinomyces oris species Decreases
0 1 Ruthenibacterium lactatiformans species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Parvimonas micra species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Paraprevotella clara species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Anaerostipes caccae species Decreases
0 1 Prevotella bivia species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Alistipes ihumii species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Corynebacterium durum species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Butyricimonas virosa species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Olsenella uli species Decreases
0 1 Blautia hansenii species Decreases
0 1 Alistipes communis species Decreases
0 1 Bacteroides nordii species Decreases
0 1 Streptococcus pasteurianus species Decreases
0 1 Blautia producta species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Alistipes senegalensis species Decreases
0 1 Treponema denticola species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Prevotella dentalis species Decreases
0 1 Bifidobacterium bifidum species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of norcyclobenzaprine,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.6 0.6
Acne 0.3 -0.3
ADHD 4.3 1 3.3
Age-Related Macular Degeneration and Glaucoma 0.9 0.2 3.5
Allergic Rhinitis (Hay Fever) 2.3 2.3 0
Allergies 7.5 3.9 0.92
Allergy to milk products 2.2 1.1 1
Alopecia (Hair Loss) 1.7 0.1 16
Alzheimer's disease 7 7.1 -0.01
Amyotrophic lateral sclerosis (ALS) Motor Neuron 3.9 0.9 3.33
Ankylosing spondylitis 4.9 1.2 3.08
Anorexia Nervosa 1.4 3.8 -1.71
Antiphospholipid syndrome (APS) 0.9 0.9
Asthma 5.9 3.3 0.79
Atherosclerosis 2.7 2 0.35
Atrial fibrillation 4.1 2.2 0.86
Autism 10.7 10.6 0.01
Autoimmune Disease 0.4 1.1 -1.75
Barrett esophagus cancer 0.6 0.6
benign prostatic hyperplasia 0.1 0.4 -3
Biofilm 1.1 1.1
Bipolar Disorder 1.9 1.7 0.12
Brain Trauma 0.8 1.4 -0.75
Breast Cancer 0.5 0.5
Cancer (General) 1 2.6 -1.6
Carcinoma 3.7 2.6 0.42
Celiac Disease 3.2 4.1 -0.28
Cerebral Palsy 2 1.4 0.43
Chronic Fatigue Syndrome 6.1 6.8 -0.11
Chronic Kidney Disease 3.9 3.1 0.26
Chronic Lyme 0.6 0.8 -0.33
Chronic Obstructive Pulmonary Disease (COPD) 1.1 1.7 -0.55
Chronic Urticaria (Hives) 1 2 -1
Coagulation / Micro clot triggering bacteria 0.4 1.2 -2
Cognitive Function 1.9 1.5 0.27
Colorectal Cancer 6.2 3.1 1
Constipation 1.7 0.8 1.13
Coronary artery disease 1.4 3.9 -1.79
COVID-19 11.7 14.7 -0.26
Crohn's Disease 8.7 7.3 0.19
Cushing's Syndrome (hypercortisolism) 1 -1
cystic fibrosis 0.2 1.9 -8.5
d-lactic acidosis (one form of brain fog) 0.1 0.1
deep vein thrombosis 1.9 1.2 0.58
Denture Wearers Oral Shifts 1.2 1.2
Depression 12 10 0.2
Dermatomyositis 0.3 -0.3
Eczema 1.2 1.8 -0.5
Endometriosis 2.2 2.2 0
Eosinophilic Esophagitis 0.2 0.4 -1
Epilepsy 3.8 2.5 0.52
erectile dysfunction 1 0.3 2.33
Fibromyalgia 3.9 2.7 0.44
Functional constipation / chronic idiopathic constipation 5.4 4.6 0.17
gallstone disease (gsd) 2.9 1.4 1.07
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 2.3 1.8 0.28
Generalized anxiety disorder 2.3 2.3 0
giant cell arteritis 0.4 -0.4
Gout 1.7 1.1 0.55
Graves' disease 1.9 3.1 -0.63
Gulf War Syndrome 1 2.7 -1.7
Halitosis 1.3 1.3
Hashimoto's thyroiditis 4 1.9 1.11
Heart Failure 3.3 2.8 0.18
hemorrhagic stroke 0.7 0.7
Hidradenitis Suppurativa 1 0.4 1.5
High Histamine/low DAO 1.5 0.5 2
hypercholesterolemia (High Cholesterol) 0.9 0.7 0.29
hyperglycemia 1.2 2.5 -1.08
Hyperlipidemia (High Blood Fats) 1.2 0.4 2
hypersomnia 0.1 0.8 -7
hypertension (High Blood Pressure 4.1 6.6 -0.61
Hypothyroidism 0.9 1.5 -0.67
Hypoxia 2.7 2.7
IgA nephropathy (IgAN) 1.5 5.7 -2.8
Inflammatory Bowel Disease 9.3 11.3 -0.22
Insomnia 1.9 4.1 -1.16
Intelligence 1.9 0.7 1.71
Intracranial aneurysms 1.4 0.7 1
Irritable Bowel Syndrome 7.7 6.6 0.17
ischemic stroke 2.6 1.4 0.86
Liver Cirrhosis 7.3 4.4 0.66
Long COVID 9 9.2 -0.02
Low bone mineral density 1.4 -1.4
Lung Cancer 0.7 1.9 -1.71
Lymphoma 0.1 0.1 0
Mast Cell Issues / mastitis 0.4 0.7 -0.75
ME/CFS with IBS 1.1 3 -1.73
ME/CFS without IBS 1.6 2.5 -0.56
Menopause 2 1 1
Metabolic Syndrome 7.2 9.2 -0.28
Mood Disorders 12.6 8.5 0.48
multiple chemical sensitivity [MCS] 0.9 0.5 0.8
Multiple Sclerosis 6.9 7.2 -0.04
Multiple system atrophy (MSA) 1.8 0.9 1
myasthenia gravis 0.1 0.8 -7
neuropathic pain 0.5 3.6 -6.2
Neuropathy (all types) 1.3 1.4 -0.08
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 5.7 6.4 -0.12
NonCeliac Gluten Sensitivity 2.5 0.7 2.57
Obesity 11.1 8.7 0.28
obsessive-compulsive disorder 6.1 3.6 0.69
Osteoarthritis 2.8 1.6 0.75
Osteoporosis 2.3 1.9 0.21
pancreatic cancer 0.7 0.7
Parkinson's Disease 8.8 8.3 0.06
Polycystic ovary syndrome 5.8 3.2 0.81
Postural orthostatic tachycardia syndrome 0.4 0.6 -0.5
Premenstrual dysphoric disorder 1.1 0.2 4.5
primary biliary cholangitis 0.8 1.5 -0.88
Primary sclerosing cholangitis 2.5 3 -0.2
Psoriasis 4.2 3.7 0.14
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 7.7 5.3 0.45
Rosacea 0.7 0.9 -0.29
Schizophrenia 8.2 3.9 1.1
scoliosis 0.5 0.8 -0.6
sensorineural hearing loss 0.3 0.3
Sjögren syndrome 3 3.1 -0.03
Sleep Apnea 1.7 1.8 -0.06
Slow gastric motility / Gastroparesis 1.1 0.3 2.67
Small Intestinal Bacterial Overgrowth (SIBO) 1.9 0.6 2.17
Stress / posttraumatic stress disorder 2.8 3.2 -0.14
Systemic Lupus Erythematosus 3.9 3 0.3
Tic Disorder 1.1 2.1 -0.91
Tourette syndrome 0.8 0.4 1
Type 1 Diabetes 4.6 4.3 0.07
Type 2 Diabetes 9.1 8 0.14
Ulcerative colitis 6.5 9.2 -0.42
Unhealthy Ageing 5 2.8 0.79
Vitiligo 2.2 1.8 0.22

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