🍽️ ribostamycin sulfate salt (antibiotic)

Bacterial Infections: Ribostamycin sulfate salt is primarily used to treat bacterial infections caused by susceptible organisms. It is effective against various bacteria, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus species, and certain strains of Staphylococcus aureus.

Respiratory Tract Infections: Ribostamycin sulfate salt may be prescribed for the treatment of respiratory tract infections, including pneumonia, bronchitis, and bronchiectasis, especially when caused by gram-negative bacteria.

Urinary Tract Infections: It can also be used to treat urinary tract infections caused by susceptible organisms, such as Escherichia coli and Proteus species.

Skin and Soft Tissue Infections: Ribostamycin sulfate salt may be effective in the treatment of skin and soft tissue infections caused by susceptible bacteria, including infected wounds, abscesses, and cellulitis.

Otitis Externa: It can be used topically or systemically to treat otitis externa (outer ear infections) caused by susceptible bacteria.

Ophthalmic Infections: Ribostamycin sulfate salt may also be formulated into ophthalmic preparations for the treatment of bacterial eye infections, such as conjunctivitis and keratitis.

Cystic Fibrosis: In some cases, ribostamycin sulfate salt may be used in the management of respiratory infections in patients with cystic fibrosis, particularly those caused by Pseudomonas aeruginosa.

Hospital-Acquired Infections: It may be used in the treatment of hospital-acquired infections, including those associated with ventilator-associated pneumonia and catheter-related bloodstream infections, especially when caused by multidrug-resistant gram-negative bacteria.

Side Effects: Like other aminoglycoside antibiotics, ribostamycin sulfate salt can cause side effects, including nephrotoxicity (kidney damage), ototoxicity (hearing loss or balance problems), and neurotoxicity (nervous system side effects). These side effects are dose-dependent and more likely to occur with prolonged use or in patients with pre-existing kidney or hearing impairment.

Pregnancy and Lactation: Ribostamycin sulfate salt should be used with caution in pregnant women, as it may cross the placenta and cause harm to the developing fetus. It may also be excreted in breast milk, so nursing mothers should consult their healthcare provider before using this medication.

Drug Interactions: Ribostamycin sulfate salt may interact with other medications, particularly those that affect renal function or have ototoxic or nephrotoxic effects. Concurrent use with other nephrotoxic or ototoxic drugs should be avoided to minimize the risk of adverse effects.

Dosage and Administration: The dosage and administration of ribostamycin sulfate salt depend on the type and severity of the infection, as well as the patient's age, weight, renal function, and other factors. It is usually administered parenterally (via injection or infusion) or topically (in the case of ophthalmic or otic preparations).