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🍽️ fadrozole hydrochloride,(prescription)

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  1. Breast Cancer Treatment: Fadrozole hydrochloride is primarily used in the treatment of hormone-sensitive breast cancer, particularly in postmenopausal women. By blocking the production of estrogen, it helps to inhibit the growth of estrogen-dependent breast tumors.

  2. Aromatase Inhibition: Fadrozole hydrochloride inhibits the activity of the aromatase enzyme, which is responsible for converting androgens (such as testosterone) into estrogens (such as estradiol). This inhibition reduces estrogen levels in the body, which is beneficial in estrogen-dependent breast cancer.

  3. Adjuvant Therapy: Fadrozole hydrochloride may be used as adjuvant therapy following surgery or other primary treatments for breast cancer to reduce the risk of cancer recurrence.

  4. Advanced or Metastatic Breast Cancer: Fadrozole hydrochloride may also be used in the treatment of advanced or metastatic breast cancer that has spread to other parts of the body. It can help slow down the progression of the disease and alleviate symptoms.

  5. Hormone Receptor-Positive Breast Cancer: Fadrozole hydrochloride is most effective in treating hormone receptor-positive breast cancer, where the cancer cells have receptors for estrogen or progesterone. It is less effective in hormone receptor-negative breast cancer.

  6. Estrogen Suppression: By lowering estrogen levels in the body, fadrozole hydrochloride may cause menopausal-like symptoms such as hot flashes, vaginal dryness, and mood changes. These side effects are usually temporary and can often be managed with supportive care or other medications.

  7. Bone Health: Estrogen plays a crucial role in maintaining bone density, and reducing estrogen levels with fadrozole hydrochloride may lead to bone loss and an increased risk of osteoporosis. Bone density monitoring and supplementation with calcium and vitamin D may be recommended to mitigate this risk.

  8. Cardiovascular Effects: Estrogen has protective effects on the cardiovascular system, and reducing estrogen levels with fadrozole hydrochloride may increase the risk of cardiovascular events such as heart disease and stroke. Monitoring of cardiovascular health and appropriate interventions may be necessary in patients receiving fadrozole hydrochloride.

  9. Liver Function: Fadrozole hydrochloride is metabolized in the liver, so monitoring of liver function tests may be necessary during treatment to detect any signs of liver toxicity.

  10. Interactions: Fadrozole hydrochloride may interact with other medications, including tamoxifen and other hormonal therapies. It's essential to inform your healthcare provider about all medications you are taking before starting fadrozole hydrochloride.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of fadrozole hydrochloride,(prescription) On Probiotics

Rank Probiotic Impact
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces

Bacteria Impacted by fadrozole hydrochloride,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Escherichia genus Decreases
0 1 Bilophila genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Streptococcus genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Escherichia coli species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Fusobacterium nucleatum species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of fadrozole hydrochloride,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.3 0.3
ADHD 0.6 0.6
Allergic Rhinitis (Hay Fever) 1.1 0.6 0.83
Allergies 1.1 0.3 2.67
Allergy to milk products 0.2 0.6 -2
Alzheimer's disease 1.2 0.9 0.33
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.6 0.2 2
Ankylosing spondylitis 1.1 0.5 1.2
Anorexia Nervosa 0.3 0.3 0
Antiphospholipid syndrome (APS) 0.5 0.3 0.67
Asthma 1.4 0.3 3.67
Atherosclerosis 0.5 0.5
Atrial fibrillation 0.3 0.9 -2
Autism 1.4 1.7 -0.21
Autoimmune Disease 0.9 0.9
Barrett esophagus cancer 0.3 0.3 0
benign prostatic hyperplasia 0.6 0.6
Biofilm 0.8 0.8
Bipolar Disorder 0.9 0.9
Brain Trauma 0.3 0.3
Breast Cancer 0.2 0.2
Cancer (General) 0.3 0.6 -1
Carcinoma 1.5 1.5
Celiac Disease 0.5 0.3 0.67
Cerebral Palsy 0.3 0.3
Chronic Fatigue Syndrome 1.1 0.3 2.67
Chronic Kidney Disease 0.8 0.3 1.67
Chronic Obstructive Pulmonary Disease (COPD) 1.5 0.6 1.5
Chronic Urticaria (Hives) 1.1 1.1
Coagulation / Micro clot triggering bacteria 1.1 0.3 2.67
Cognitive Function 0.3 0.3 0
Colorectal Cancer 2.4 0.2 11
Constipation 0.6 0.6
Coronary artery disease 1.3 1.3
COVID-19 1.4 1.1 0.27
Crohn's Disease 1.9 0.3 5.33
cystic fibrosis 0.8 0.8
d-lactic acidosis (one form of brain fog) 0.2 0.2
deep vein thrombosis 0.8 0.3 1.67
Denture Wearers Oral Shifts 0.9 0.9
Depression 2.3 1.5 0.53
Dermatomyositis 0.3 0.3
Eczema 1.4 0.9 0.56
Endometriosis 1.1 0.2 4.5
Eosinophilic Esophagitis 0.3 0.3 0
Epilepsy 1.4 1.4
erectile dysfunction 0.9 0.9
Functional constipation / chronic idiopathic constipation 1.1 1.1
gallstone disease (gsd) 1.1 0.3 2.67
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.3 0.3 0
Generalized anxiety disorder 1.6 0.3 4.33
Glioblastoma 0.3 -0.3
Gout 0.3 0.3
Graves' disease 0.3 -0.3
Gulf War Syndrome 0.3 0.3
Halitosis 0.6 0.3 1
Hashimoto's thyroiditis 0.3 0.3 0
Heart Failure 1.4 1.4
hemorrhagic stroke 0.3 0.3
Hidradenitis Suppurativa 0.9 0.9
High Histamine/low DAO 0.2 0.2
hypercholesterolemia (High Cholesterol) 0.2 0.2
hyperglycemia 1.4 1.4
Hyperlipidemia (High Blood Fats) 0.3 0.3
hypersomnia 0.3 -0.3
hypertension (High Blood Pressure 0.9 0.6 0.5
Hypoxia 0.8 0.8
IgA nephropathy (IgAN) 0.6 0.2 2
Inflammatory Bowel Disease 2.2 0.9 1.44
Insomnia 0.9 0.3 2
Intelligence 0.2 0.2
Intracranial aneurysms 0.3 0.3
Irritable Bowel Syndrome 1.4 0.3 3.67
ischemic stroke 0.5 0.6 -0.2
Liver Cirrhosis 2.3 1.1 1.09
Long COVID 1.4 0.6 1.33
Lung Cancer 0.9 0.9
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 0.9 0.9
ME/CFS with IBS 0.3 0.3
ME/CFS without IBS 0.5 0.5
membranous nephropathy 0.3 0.3
Menopause 0.3 0.3
Metabolic Syndrome 2 0.9 1.22
Mood Disorders 2.1 1.5 0.4
multiple chemical sensitivity [MCS] 0.9 0.9
Multiple Sclerosis 2.1 0.3 6
Multiple system atrophy (MSA) 0 0
myasthenia gravis 0.9 0.9
Neuropathy (all types) 0.3 0.6 -1
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.4 1.4
Obesity 1.9 2 -0.05
obsessive-compulsive disorder 1.1 0.5 1.2
Osteoarthritis 1.1 0.3 2.67
Osteoporosis 0.6 0.3 1
pancreatic cancer 0.3 0.3 0
Parkinson's Disease 2 1.2 0.67
Polycystic ovary syndrome 1.4 0.6 1.33
primary biliary cholangitis 0.3 0.6 -1
Primary sclerosing cholangitis 0.6 0.2 2
Psoriasis 0.5 0.5
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1.4 0.3 3.67
Schizophrenia 0.9 0.9
scoliosis 0.2 0.3 -0.5
Sjögren syndrome 0.9 0.9
Sleep Apnea 0.3 0.3
Slow gastric motility / Gastroparesis 0.2 0.2
Small Intestinal Bacterial Overgrowth (SIBO) 0.8 0.8
Stress / posttraumatic stress disorder 0.5 0.5
Systemic Lupus Erythematosus 1.7 1.7
Tic Disorder 0.3 0.3
Tourette syndrome 0.3 0.3
Type 1 Diabetes 1.2 0.3 3
Type 2 Diabetes 1.9 0.8 1.37
Ulcerative colitis 1.1 0.3 2.67
Unhealthy Ageing 1.1 1.1
Vitiligo 0.3 0.3

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