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Trazodone is primarily indicated for the treatment of depression, including both the acute phase and the maintenance phase of major depressive disorder (MDD). It helps alleviate symptoms such as persistent sadness, loss of interest or pleasure in activities, changes in appetite or sleep patterns, and feelings of worthlessness or guilt.
Anxiety Disorders:
Trazodone may be used off-label to manage symptoms of anxiety disorders such as generalized anxiety disorder (GAD), panic disorder, and social anxiety disorder (SAD). It can help reduce anxiety symptoms such as excessive worry, nervousness, and restlessness.
Insomnia:
Trazodone is often prescribed off-label to treat insomnia, particularly in individuals with depression who experience sleep disturbances. It can help improve sleep quality and duration by promoting drowsiness and facilitating sleep onset.
Sleep Disorders:
Trazodone may be used off-label in the treatment of certain sleep disorders, such as sleep disturbances associated with post-traumatic stress disorder (PTSD) and nightmares. It can help reduce the frequency and intensity of nightmares and improve overall sleep quality.
Pain Management:
Trazodone may be used off-label to manage chronic pain conditions, particularly neuropathic pain. It can help alleviate pain symptoms and improve overall quality of life in individuals with conditions such as fibromyalgia, diabetic neuropathy, and chronic back pain.
Adjunctive Therapy:
Trazodone may be used as an adjunctive treatment alongside other antidepressant medications or mood stabilizers to enhance therapeutic effects or manage specific symptoms. It may be prescribed in cases where standard antidepressant therapy alone is insufficient.
Side Effects:
Common side effects of trazodone may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and weight changes. Less common but potentially serious side effects may include serotonin syndrome (especially when used in combination with other serotonergic medications), priapism (prolonged erection), and orthostatic hypotension (drop in blood pressure upon standing).
Bacteria Impacted by trazodone hydrochloride,(prescription)
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of trazodone hydrochloride,(prescription) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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