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🍽️ guanadrel sulfate,(prescription)

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  1. Mechanism of Action: Guanadrel sulfate belongs to a class of medications known as sympatholytics or adrenergic neuron blockers. It works by inhibiting the release of norepinephrine from nerve endings, which reduces sympathetic nervous system activity. This leads to vasodilation (widening of blood vessels) and a subsequent decrease in blood pressure.

  2. Treatment of Hypertension: Guanadrel sulfate was historically used as an antihypertensive medication to lower blood pressure in patients with essential hypertension (high blood pressure without an identifiable cause). It was particularly useful in patients who did not respond adequately to other antihypertensive agents.

  3. Limited Use: Despite its efficacy in lowering blood pressure, guanadrel sulfate is rarely used today due to several limitations and side effects associated with its use. These include the need for frequent dosing, slow onset of action, and a high incidence of adverse effects.

  4. Adverse Effects: Guanadrel sulfate can cause a range of side effects, some of which can be severe. Common side effects include orthostatic hypotension (a sudden drop in blood pressure upon standing), dizziness, lightheadedness, weakness, fatigue, gastrointestinal disturbances (such as nausea and diarrhea), and sexual dysfunction.

  5. Orthostatic Hypotension: Orthostatic hypotension is one of the most significant side effects of guanadrel sulfate. It occurs due to the medication's ability to reduce sympathetic tone, leading to inadequate compensation for changes in body position. Patients may experience symptoms such as dizziness, lightheadedness, or fainting when transitioning from lying down to standing up.

  6. Central Nervous System Effects: Guanadrel sulfate can cross the blood-brain barrier and exert effects on the central nervous system. This may result in side effects such as sedation, confusion, depression, and cognitive impairment.

  7. Cardiovascular Effects: In addition to lowering blood pressure, guanadrel sulfate may also affect heart rate and rhythm. It can cause bradycardia (slow heart rate) and may exacerbate conduction abnormalities in patients with pre-existing cardiac conditions.

  8. Withdrawal Rebound Hypertension: Abrupt discontinuation of guanadrel sulfate can lead to rebound hypertension, characterized by a sudden and significant increase in blood pressure. Therefore, the medication should be tapered off gradually under medical supervision when discontinuing treatment.

  9. Contraindications and Precautions: Guanadrel sulfate is contraindicated in patients with hypersensitivity to the medication, severe bradycardia, heart block, or pheochromocytoma (a rare adrenal gland tumor). It should be used with caution in patients with pre-existing cardiovascular disease, renal impairment, or hepatic impairment.

  10. Interactions with Other Medications: Guanadrel sulfate may interact with other medications that affect blood pressure or sympathetic nervous system activity. Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking before starting guanadrel sulfate.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of guanadrel sulfate,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium bifidum Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium catenulatum Reduces
species Bifidobacterium longum Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Lactococcus lactis Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces
species Veillonella atypica Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by guanadrel sulfate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Collinsella genus Decreases
0 1 Blautia genus Decreases
0 1 Veillonella genus Decreases
0 1 Dorea genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Escherichia genus Decreases
0 1 Eggerthella genus Decreases
0 1 Clostridioides genus Decreases
0 1 Streptococcus genus Decreases
0 1 Shigella genus Decreases
0 1 Roseburia genus Decreases
0 1 Bacteroides genus Decreases
0 1 Odoribacter genus Decreases
0 1 Enterocloster genus Decreases
0 1 Parolsenella genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Olsenella genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Fannyhessea genus Decreases
0 1 Faecalibaculum genus Decreases
0 1 Lactococcus genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Clostridium genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Agathobacter genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Roseburia hominis species Decreases
1 0 Clostridioides difficile species Decreases
1 0 Bacteroides ovatus species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Blautia obeum species Decreases
1 0 Collinsella aerofaciens species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Escherichia coli species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Veillonella parvula species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Bacteroides xylanisolvens species Decreases
1 0 Odoribacter splanchnicus species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Bacteroides uniformis species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Veillonella rodentium species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Phocaeicola vulgatus species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Veillonella dispar species Decreases
0 1 Eggerthella guodeyinii species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Shigella boydii species Decreases
0 1 Veillonella sp. S12025-13 species Decreases
0 1 Bifidobacterium angulatum species Decreases
0 1 Veillonella nakazawae species Decreases
0 1 Parolsenella catena species Decreases
1 0 [Ruminococcus] torques species Decreases
0 1 Coprococcus catus species Decreases
0 1 Veillonella rogosae species Decreases
0 1 Dorea longicatena species Decreases
0 1 Parolsenella massiliensis species Decreases
0 1 Wansuia hejianensis species Decreases
1 0 Roseburia intestinalis species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Collinsella stercoris species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Coprococcus comes species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
1 0 Mediterraneibacter gnavus species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Shigella sonnei species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Veillonella atypica species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Bacteroides sp. DH3716P species Decreases
0 1 Bacteroides sp. D2 species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Bifidobacterium catenulatum species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Christensenella minuta species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Ruthenibacterium lactatiformans species Decreases
0 1 Actinomyces oris species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Blautia liquoris species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Parvimonas micra species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
1 0 Parabacteroides distasonis species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Bacteroides sp. M10 species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Enterocloster clostridioformis species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Bifidobacterium bifidum species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Parafannyhessea umbonata species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Amedibacterium intestinale species Decreases
0 1 Hungatella hathewayi species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Streptococcus suis species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Lactococcus lactis species Decreases
0 1 Alistipes ihumii species Decreases
0 1 Dysosmobacter welbionis species Decreases
0 1 Flavonifractor plautii species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Treponema denticola species Decreases
0 1 Streptococcus australis species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Gordonibacter urolithinfaciens species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Alistipes communis species Decreases
0 1 Alistipes senegalensis species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Campylobacter coli species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Alistipes sp. dk3624 species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Treponema peruense species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Enterocloster asparagiformis species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Alistipes shahii species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Selenomonas sputigena species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Alistipes finegoldii species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Alistipes dispar species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Streptococcus pasteurianus species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Arabiibacter massiliensis species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Enterococcus faecium species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Rothia dentocariosa species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
1 0 Clostridium perfringens species Decreases
0 1 Emergencia timonensis species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Lacrimispora saccharolytica species Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of guanadrel sulfate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.1 0.1
Acne 0.4 -0.4
ADHD 3.4 0.7 3.86
Age-Related Macular Degeneration and Glaucoma 0.8 0.1 7
Allergic Rhinitis (Hay Fever) 2.7 3.2 -0.19
Allergies 6.9 1.3 4.31
Allergy to milk products 1.4 1.3 0.08
Alopecia (Hair Loss) 1.6 0.1 15
Alzheimer's disease 4.7 5.1 -0.09
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.9 0.7 1.71
Ankylosing spondylitis 4.1 0.4 9.25
Anorexia Nervosa 1.3 1.7 -0.31
Antiphospholipid syndrome (APS) 1.2 1.2
Asthma 5.5 2.1 1.62
Atherosclerosis 2.3 0.8 1.87
Atrial fibrillation 2.7 1.4 0.93
Autism 7.2 6.2 0.16
Autoimmune Disease 1.3 0.7 0.86
Barrett esophagus cancer 0.5 0.3 0.67
benign prostatic hyperplasia 0.6 0.2 2
Biofilm 2.1 2.1
Bipolar Disorder 1.3 1 0.3
Brain Trauma 1.3 0.8 0.63
Breast Cancer 0.7 0.7
Cancer (General) 0.7 2.7 -2.86
Carcinoma 3.4 2.3 0.48
Celiac Disease 3 2.8 0.07
Cerebral Palsy 1.4 0.9 0.56
Chronic Fatigue Syndrome 5.5 4.8 0.15
Chronic Kidney Disease 4.3 1.2 2.58
Chronic Lyme 0.6 0.4 0.5
Chronic Obstructive Pulmonary Disease (COPD) 2.4 1 1.4
Chronic Urticaria (Hives) 1.7 0.3 4.67
Coagulation / Micro clot triggering bacteria 1.6 1.1 0.45
Cognitive Function 2 1.2 0.67
Colorectal Cancer 5.4 2.3 1.35
Constipation 1.1 0.7 0.57
Coronary artery disease 2.3 2.1 0.1
COVID-19 9.6 9.5 0.01
Crohn's Disease 6.5 3.4 0.91
Cushing's Syndrome (hypercortisolism) 0.5 -0.5
cystic fibrosis 1 1.9 -0.9
d-lactic acidosis (one form of brain fog) 0.7 0.7
deep vein thrombosis 1.7 0.8 1.13
Denture Wearers Oral Shifts 1.8 1.8
Depression 9.5 7.2 0.32
Dermatomyositis 0.3 0.4 -0.33
Eczema 1.6 2.2 -0.38
Endometriosis 3.2 1.5 1.13
Eosinophilic Esophagitis 0 0.7 0
Epilepsy 3.7 1.5 1.47
erectile dysfunction 0.9 0.5 0.8
Fibromyalgia 2.8 1.3 1.15
Functional constipation / chronic idiopathic constipation 4.6 2.6 0.77
gallstone disease (gsd) 3 0.7 3.29
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.1 1.5 -0.36
Generalized anxiety disorder 2.7 1.5 0.8
giant cell arteritis 0.1 -0.1
Glioblastoma 0.3 -0.3
Gout 1.5 0.3 4
Graves' disease 1.6 3 -0.88
Gulf War Syndrome 0.8 0.8 0
Halitosis 1.1 0.4 1.75
Hashimoto's thyroiditis 2.8 0.8 2.5
Heart Failure 2.7 1.4 0.93
hemorrhagic stroke 0.6 0.6
Hidradenitis Suppurativa 0.5 0.4 0.25
High Histamine/low DAO 1 0.4 1.5
hypercholesterolemia (High Cholesterol) 0.9 0.1 8
hyperglycemia 2.5 1.2 1.08
Hyperlipidemia (High Blood Fats) 1 0.5 1
hypersomnia 1.1 -1.1
hypertension (High Blood Pressure 3.7 4.4 -0.19
Hypothyroidism 1.2 -1.2
Hypoxia 1.3 1.3
IgA nephropathy (IgAN) 1.1 3.1 -1.82
Inflammatory Bowel Disease 8.6 6.6 0.3
Insomnia 2.6 1.8 0.44
Intelligence 1.5 1.5
Intracranial aneurysms 0.8 0.6 0.33
Irritable Bowel Syndrome 6.1 3.4 0.79
ischemic stroke 3.1 1.2 1.58
Juvenile idiopathic arthritis 0.1 0.1
Liver Cirrhosis 6.5 2.8 1.32
Long COVID 5.7 5.5 0.04
Low bone mineral density 0.1 0.5 -4
Lung Cancer 1.2 1 0.2
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 1 0.4 1.5
ME/CFS with IBS 0.7 2.5 -2.57
ME/CFS without IBS 1.6 1.9 -0.19
membranous nephropathy 0.3 0.3
Menopause 2.5 0.4 5.25
Metabolic Syndrome 6.5 6.4 0.02
Mood Disorders 9.1 5.9 0.54
multiple chemical sensitivity [MCS] 1.4 0.5 1.8
Multiple Sclerosis 6.3 3.1 1.03
Multiple system atrophy (MSA) 1 0.8 0.25
myasthenia gravis 0.9 0.3 2
neuropathic pain 0.4 1.9 -3.75
Neuropathy (all types) 1.1 1.1 0
neuropsychiatric disorders (PANDAS, PANS) 1.1 1.1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 4.6 3.7 0.24
NonCeliac Gluten Sensitivity 1.9 0.6 2.17
Obesity 8.5 6.3 0.35
obsessive-compulsive disorder 5 2.3 1.17
Osteoarthritis 2.1 1 1.1
Osteoporosis 1.9 1.7 0.12
pancreatic cancer 0.6 0.3 1
Parkinson's Disease 7.5 4.3 0.74
Polycystic ovary syndrome 4.2 1.8 1.33
Postural orthostatic tachycardia syndrome 0.1 0.4 -3
Premenstrual dysphoric disorder 1.3 0.1 12
primary biliary cholangitis 1.1 1.2 -0.09
Primary sclerosing cholangitis 2.4 1.8 0.33
Psoriasis 3.7 0.8 3.63
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 5.7 3.5 0.63
Rosacea 0.7 0.3 1.33
Schizophrenia 5.7 1.9 2
scoliosis 0.8 0.8
sensorineural hearing loss 0.3 0.3
Sjögren syndrome 3 2.5 0.2
Sleep Apnea 1.5 1.2 0.25
Slow gastric motility / Gastroparesis 1.3 0.4 2.25
Small Intestinal Bacterial Overgrowth (SIBO) 1.7 0.6 1.83
Stress / posttraumatic stress disorder 2.3 2 0.15
Systemic Lupus Erythematosus 3.3 1.4 1.36
Tic Disorder 0.7 1.6 -1.29
Tourette syndrome 0.7 0.2 2.5
Type 1 Diabetes 3.3 3 0.1
Type 2 Diabetes 7.3 5.2 0.4
Ulcerative colitis 4.9 4.5 0.09
Unhealthy Ageing 3.9 1.1 2.55
Vitiligo 1.3 0.7 0.86

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