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🍽️ d-cycloserine (antibiotic)

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  1. Tuberculosis (TB): D-Cycloserine is used as a second-line treatment for tuberculosis, especially when first-line drugs such as isoniazid and rifampicin are ineffective or when the TB bacteria are resistant to them. It works by inhibiting the synthesis of mycobacterial cell walls, thereby killing the bacteria or preventing their growth.

  2. Multi-Drug Resistant Tuberculosis (MDR-TB): D-Cycloserine is particularly useful in the treatment of multi-drug resistant tuberculosis (MDR-TB), a form of TB that is resistant to at least isoniazid and rifampicin, the two most potent anti-TB drugs. D-Cycloserine is often used in combination with other second-line drugs to effectively treat MDR-TB infections.

  3. Extensively Drug Resistant Tuberculosis (XDR-TB): D-Cycloserine may also be used in the treatment of extensively drug-resistant tuberculosis (XDR-TB), which is resistant to multiple first-line and second-line anti-TB drugs. In combination with other antibiotics, d-cycloserine can help combat XDR-TB infections.

  4. Adverse Effects: Common side effects of d-cycloserine include dizziness, drowsiness, headache, nausea, vomiting, and diarrhea. It can also cause neurological side effects such as confusion, depression, anxiety, and hallucinations, particularly at higher doses. Long-term use of d-cycloserine may lead to peripheral neuropathy.

  5. Monitoring: Patients taking d-cycloserine should be closely monitored for adverse effects, especially neurological side effects. Regular assessment of kidney function and liver function may also be necessary. Dosage adjustments or discontinuation of the medication may be required if severe adverse effects occur.

  6. Drug Interactions: D-Cycloserine may interact with other medications, including certain antidepressants, antipsychotics, and anticonvulsants, potentially leading to increased side effects or reduced efficacy of either drug. Healthcare providers should be aware of potential drug interactions and adjust medication doses as needed.

  7. Treatment Duration: The duration of treatment with d-cycloserine for tuberculosis varies depending on the severity of the infection, the presence of drug resistance, and other factors. Treatment regimens are typically prolonged, often lasting for several months to years, and may involve combination therapy with multiple antibiotics.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of d-cycloserine (antibiotic) On Probiotics

Rank Probiotic Impact
species Anaerobutyricum hallii Reduces
species Bacteroides uniformis Reduces
species Blautia hansenii Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Escherichia coli Reduces
species Faecalibacterium prausnitzii Reduces
species Lactococcus cremoris Reduces
species Lactococcus lactis Reduces
species Streptococcus thermophilus Reduces

Bacteria Impacted by d-cycloserine (antibiotic)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Phocaeicola genus Decreases
0 1 Roseburia genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Coprococcus genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Escherichia genus Decreases
0 1 Segatella genus Decreases
0 1 Bacteroides genus Decreases
0 1 Streptococcus genus Decreases
0 1 Bilophila genus Decreases
0 1 Shigella genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Wujia genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Eubacterium genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Simiaoa genus Decreases
0 1 Lachnospira genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Wansuia genus Decreases
0 1 Clostridium genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Coprococcus comes species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Escherichia coli species Decreases
1 0 Segatella copri species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bilophila wadsworthia species Decreases
0 1 Coprococcus catus species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Dorea longicatena species Decreases
0 1 Blautia argi species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Blautia obeum species Decreases
0 1 Dorea formicigenerans species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Roseburia hominis species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Shigella flexneri species Decreases
0 1 [Ruminococcus] torques species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Escherichia albertii species Decreases
0 1 Streptococcus suis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Blautia liquoris species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Christensenella minuta species Decreases
0 1 Chordicoccus furentiruminis species Decreases
1 0 Clostridium perfringens species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Treponema peruense species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Acutalibacter muris species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Parvimonas micra species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Segatella bryantii species Decreases
0 1 Lachnospira eligens species Decreases
0 1 Enterococcus faecium species Decreases
1 0 Bacteroides uniformis species Decreases
0 1 Shigella boydii species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Treponema denticola species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Actinomyces oris species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Blautia hansenii species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Emergencia timonensis species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Leyella stercorea species Decreases
0 1 Blautia parvula species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Phascolarctobacterium sp. Marseille-Q4147 species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Blautia producta species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Butyricicoccus sp. GAM44 species Decreases
0 1 Thomasclavelia ramosa species Decreases
0 1 Romboutsia ilealis species Decreases
0 1 Blautia pseudococcoides species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 [Clostridium] scindens species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Enterocloster bolteae species Decreases
0 1 Anaerostipes caccae species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Alistipes ihumii species Decreases
0 1 Shigella sonnei species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Romboutsia sp. 13368 species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Rothia dentocariosa species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Clostridioides difficile species Decreases
0 1 uncultured Alistipes sp. species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Streptococcus canis species Decreases
0 1 Pusillibacter faecalis species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Lactococcus lactis species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Alistipes dispar species Decreases
0 1 Campylobacter coli species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of d-cycloserine (antibiotic) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.7 0.7
ADHD 1.2 0.9 0.33
Age-Related Macular Degeneration and Glaucoma 0.6 0.6
Allergic Rhinitis (Hay Fever) 1.8 1 0.8
Allergies 3.1 1.4 1.21
Allergy to milk products 1.3 0.8 0.63
Alopecia (Hair Loss) 0.1 0.2 -1
Alzheimer's disease 3.6 4.2 -0.17
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.7 0.8 1.13
Ankylosing spondylitis 1.8 1.6 0.13
Anorexia Nervosa 0.4 1.9 -3.75
Antiphospholipid syndrome (APS) 1.6 0.2 7
Asthma 3.1 1 2.1
Atherosclerosis 2.2 1.2 0.83
Atrial fibrillation 1.7 1.3 0.31
Autism 5.6 5.1 0.1
Autoimmune Disease 0.6 0.5 0.2
Barrett esophagus cancer 0.4 0.2 1
benign prostatic hyperplasia 0.4 0.2 1
Biofilm 2 2
Bipolar Disorder 1.1 0.8 0.38
Brain Trauma 0.3 0.9 -2
Breast Cancer 1.1 1.1
Cancer (General) 0.4 0.6 -0.5
Carcinoma 2.3 0.8 1.87
Celiac Disease 2.8 0.7 3
Cerebral Palsy 0.5 0.7 -0.4
Chronic Fatigue Syndrome 2.8 4 -0.43
Chronic Kidney Disease 2 1.9 0.05
Chronic Lyme 0.1 0.6 -5
Chronic Obstructive Pulmonary Disease (COPD) 2.1 1.5 0.4
Chronic Urticaria (Hives) 1 1.1 -0.1
Coagulation / Micro clot triggering bacteria 1 1.2 -0.2
Cognitive Function 0.8 0.8 0
Colorectal Cancer 6.1 1.8 2.39
Constipation 1.4 0.4 2.5
Coronary artery disease 2.2 2.3 -0.05
COVID-19 4.2 7.6 -0.81
Crohn's Disease 6.3 3.1 1.03
Cushing's Syndrome (hypercortisolism) 0.8 -0.8
cystic fibrosis 0.7 0.6 0.17
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 2.6 1.4 0.86
Denture Wearers Oral Shifts 1.6 1.6
Depression 5 4 0.25
Dermatomyositis 0.2 0.2
Eczema 1.8 1.6 0.13
Endometriosis 1.8 1.4 0.29
Eosinophilic Esophagitis 0.4 0.2 1
Epilepsy 2.8 0.3 8.33
erectile dysfunction 1.1 1.1
Fibromyalgia 0.8 1.8 -1.25
Functional constipation / chronic idiopathic constipation 4 2.8 0.43
gallstone disease (gsd) 2.4 0.9 1.67
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 2.3 1.1 1.09
Generalized anxiety disorder 2.6 1 1.6
giant cell arteritis 0.1 -0.1
Glioblastoma 0.1 0.2 -1
Gout 0.5 0.6 -0.2
Graves' disease 0.3 1.2 -3
Gulf War Syndrome 0.6 1 -0.67
Halitosis 1.5 0.3 4
Hashimoto's thyroiditis 2.2 0.9 1.44
Heart Failure 3.6 1.2 2
hemorrhagic stroke 0.5 0.5
Hidradenitis Suppurativa 1 1
High Histamine/low DAO 1.1 0.1 10
hypercholesterolemia (High Cholesterol) 0.6 0.2 2
hyperglycemia 1.4 0.3 3.67
Hyperlipidemia (High Blood Fats) 0.3 0.3
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 1.3 3.1 -1.38
Hypothyroidism 0.1 0.6 -5
Hypoxia 0.5 0.5
IgA nephropathy (IgAN) 0.9 2.7 -2
Inflammatory Bowel Disease 6.5 5.7 0.14
Insomnia 1.7 1 0.7
Intelligence 1.4 0.8 0.75
Intracranial aneurysms 0.7 0.5 0.4
Irritable Bowel Syndrome 4.6 2.7 0.7
ischemic stroke 1 1.1 -0.1
Juvenile idiopathic arthritis 0.1 -0.1
Liver Cirrhosis 4.3 2.7 0.59
Long COVID 4.7 3.6 0.31
Low bone mineral density 1.3 -1.3
Lung Cancer 0.5 0.5 0
Lymphoma 0.4 0.4
Mast Cell Issues / mastitis 1.2 0.5 1.4
ME/CFS with IBS 0.5 2.4 -3.8
ME/CFS without IBS 1.4 0.8 0.75
membranous nephropathy 0.2 0.2
Menopause 0.5 0.5 0
Metabolic Syndrome 5.1 4.4 0.16
Mood Disorders 4.6 2.6 0.77
multiple chemical sensitivity [MCS] 0.9 0.1 8
Multiple Sclerosis 3 3.5 -0.17
Multiple system atrophy (MSA) 0.3 0.1 2
myasthenia gravis 0.6 0.5 0.2
neuropathic pain 1 -1
Neuropathy (all types) 0.2 0.7 -2.5
neuropsychiatric disorders (PANDAS, PANS) 0.7 0.7
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 3.4 2.1 0.62
NonCeliac Gluten Sensitivity 0.2 0.2 0
Obesity 5.9 5.7 0.04
obsessive-compulsive disorder 3.5 2.2 0.59
Osteoarthritis 2.3 1 1.3
Osteoporosis 1.2 0.5 1.4
pancreatic cancer 0.8 0.2 3
Parkinson's Disease 5.1 5.4 -0.06
Polycystic ovary syndrome 4.5 1.2 2.75
Postural orthostatic tachycardia syndrome 0.1 0.3 -2
primary biliary cholangitis 0.3 0.8 -1.67
Primary sclerosing cholangitis 1.1 2.1 -0.91
Psoriasis 1.7 1.5 0.13
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 4.5 2.4 0.88
Rosacea 0.3 0.6 -1
Schizophrenia 2.6 1.4 0.86
scoliosis 1.2 0.4 2
sensorineural hearing loss 0.5 0.5
Sjögren syndrome 1.3 0.6 1.17
Sleep Apnea 1.2 0.9 0.33
Slow gastric motility / Gastroparesis 0.9 0.9
Small Intestinal Bacterial Overgrowth (SIBO) 2 2
Stress / posttraumatic stress disorder 1.7 1.1 0.55
Systemic Lupus Erythematosus 3.3 1 2.3
Tic Disorder 0.9 1.1 -0.22
Tourette syndrome 0.2 0.2 0
Type 1 Diabetes 2.9 2.2 0.32
Type 2 Diabetes 6.2 4.5 0.38
Ulcerative colitis 4.2 4.8 -0.14
Unhealthy Ageing 4.2 0.9 3.67
Vitiligo 1.4 0.8 0.75

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