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🍽️ quinidine hydrochloride monohydrate,(prescription)

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  1. Arrhythmias: Quinidine hydrochloride monohydrate is most commonly prescribed for the treatment of various types of cardiac arrhythmias, including atrial fibrillation, atrial flutter, and ventricular arrhythmias. It works by blocking specific ion channels in the heart muscle, which helps to stabilize the heart's electrical activity and restore normal rhythm.

  2. Atrial Fibrillation and Atrial Flutter: These are common types of irregular heart rhythms that can increase the risk of complications such as stroke and heart failure. Quinidine hydrochloride monohydrate can help to regulate the heart rate and rhythm in patients with these conditions, reducing symptoms such as palpitations, shortness of breath, and fatigue.

  3. Ventricular Arrhythmias: Ventricular arrhythmias are abnormal heart rhythms originating from the lower chambers of the heart (ventricles). These can be life-threatening and may lead to sudden cardiac arrest. Quinidine hydrochloride monohydrate can be used to suppress ventricular arrhythmias and reduce the risk of dangerous heart rhythms.

  4. Malaria: While not its primary indication, quinidine hydrochloride monohydrate has historically been used for the treatment of malaria, particularly in cases of severe or complicated malaria caused by Plasmodium falciparum. It works by interfering with the parasite's ability to replicate within red blood cells.

  5. Off-label Uses: In addition to its approved indications, quinidine hydrochloride monohydrate may be prescribed off-label for certain other conditions, such as muscle cramps, particularly those associated with conditions like myotonia congenita or paramyotonia congenita. However, the use of quinidine for these purposes is less common and may carry risks of adverse effects.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of quinidine hydrochloride monohydrate,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Anaerobutyricum hallii Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium breve Reduces
species Bifidobacterium longum Reduces
species Christensenella minuta Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by quinidine hydrochloride monohydrate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Dorea genus Decreases
0 1 Escherichia genus Decreases
0 1 Agathobacter genus Decreases
0 1 Streptococcus genus Decreases
0 1 Shigella genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Roseburia genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Coprococcus genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Segatella genus Decreases
0 1 Clostridium genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Eggerthella genus Decreases
0 1 Enterocloster genus Decreases
0 1 Bilophila genus Decreases
0 1 Bacteroides genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Clostridium perfringens A no rank Decreases
0 1 Clostridium perfringens B no rank Decreases
0 1 Clostridium perfringens C no rank Decreases
0 1 Clostridium perfringens CPE no rank Decreases
0 1 Clostridium perfringens D no rank Decreases
0 1 Clostridium perfringens E no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Bifidobacterium longum species Decreases
1 0 Dorea formicigenerans species Decreases
1 0 Escherichia coli species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Roseburia intestinalis species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Escherichia fergusonii species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Parabacteroides merdae species Decreases
0 1 Bifidobacterium breve species Decreases
0 1 Shigella boydii species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Dorea longicatena species Decreases
0 1 Blautia obeum species Decreases
0 1 Coprococcus catus species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Ligilactobacillus ruminis species Decreases
1 0 Coprococcus comes species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Shigella sonnei species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Escherichia marmotae species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 [Ruminococcus] torques species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Faecalibacillus intestinalis species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Blautia liquoris species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Christensenella minuta species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Roseburia hominis species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Streptococcus suis species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Streptococcus mutans species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Actinomyces oris species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Actinomyces sp. oral taxon 169 species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Streptococcus thermophilus species Decreases
0 1 Streptococcus australis species Decreases
1 0 Bifidobacterium adolescentis species Decreases
1 0 Segatella copri species Decreases
1 0 Clostridium perfringens species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Eggerthella lenta species Decreases
1 0 Enterocloster bolteae species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
0 1 Bifidobacterium longum subsp. infantis subspecies Decreases
0 1 Bifidobacterium longum subsp. longum subspecies Decreases
0 1 Bifidobacterium longum subsp. suillum subspecies Decreases
0 1 Bifidobacterium longum subsp. suis subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of quinidine hydrochloride monohydrate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0 0
Acne 0.2 -0.2
ADHD 1.8 0.4 3.5
Age-Related Macular Degeneration and Glaucoma 0.8 0.1 7
Allergic Rhinitis (Hay Fever) 1.6 2.1 -0.31
Allergies 3.3 0.4 7.25
Allergy to milk products 0.7 0.9 -0.29
Alopecia (Hair Loss) 0.8 0.8
Alzheimer's disease 1.8 3 -0.67
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.3 0.6 1.17
Ankylosing spondylitis 2.6 0.1 25
Anorexia Nervosa 0.6 0.8 -0.33
Antiphospholipid syndrome (APS) 1.2 0 0
Asthma 3 0.7 3.29
Atherosclerosis 0.9 0.6 0.5
Atrial fibrillation 1.4 1.6 -0.14
Autism 2.9 4.8 -0.66
Autoimmune Disease 1.1 0.4 1.75
Barrett esophagus cancer 0.3 -0.3
benign prostatic hyperplasia 0.6 0 0
Biofilm 1.3 1.3
Bipolar Disorder 0.8 0.3 1.67
Brain Trauma 0.5 0.4 0.25
Breast Cancer 0.6 0.6
Cancer (General) 1.2 -1.2
Carcinoma 1.5 0.8 0.88
Celiac Disease 1.8 1.4 0.29
Cerebral Palsy 0.5 0.2 1.5
Chronic Fatigue Syndrome 1.4 4 -1.86
Chronic Kidney Disease 1.6 1.2 0.33
Chronic Lyme 0.2 -0.2
Chronic Obstructive Pulmonary Disease (COPD) 1.9 0.5 2.8
Chronic Urticaria (Hives) 1.3 0.1 12
Coagulation / Micro clot triggering bacteria 1.6 0.4 3
Cognitive Function 1.1 0.7 0.57
Colorectal Cancer 3.8 1.6 1.37
Constipation 1 0.2 4
Coronary artery disease 2 1 1
COVID-19 4.2 5.2 -0.24
Crohn's Disease 3.7 1.8 1.06
Cushing's Syndrome (hypercortisolism) 0.4 -0.4
cystic fibrosis 1 0.5 1
d-lactic acidosis (one form of brain fog) 0.6 0.6
deep vein thrombosis 1.3 0.4 2.25
Denture Wearers Oral Shifts 1 1
Depression 4.6 4.7 -0.02
Dermatomyositis 0.3 0.2 0.5
Eczema 1 1.2 -0.2
Endometriosis 2.4 0.8 2
Eosinophilic Esophagitis 0.3 -0.3
Epilepsy 1.9 0.6 2.17
erectile dysfunction 0.6 0.2 2
Fibromyalgia 1.2 0.5 1.4
Functional constipation / chronic idiopathic constipation 3.3 0.9 2.67
gallstone disease (gsd) 1.7 0.4 3.25
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.4 0.7 -0.75
Generalized anxiety disorder 1.7 1.2 0.42
giant cell arteritis 0 0
Glioblastoma 0.3 -0.3
Gout 0.3 0.4 -0.33
Graves' disease 0.4 1.1 -1.75
Gulf War Syndrome 0.4 0.2 1
Halitosis 0.3 0.3 0
Hashimoto's thyroiditis 1.1 0.4 1.75
Heart Failure 1.8 1.1 0.64
hemorrhagic stroke 0.6 0.6
Hidradenitis Suppurativa 0.3 0.3
High Histamine/low DAO 0.9 0.2 3.5
hypercholesterolemia (High Cholesterol) 0.6 0.6
hyperglycemia 1.9 0.4 3.75
Hyperlipidemia (High Blood Fats) 0.2 0.2
hypersomnia 0 0
hypertension (High Blood Pressure 2 1.6 0.25
Hypothyroidism 0.3 -0.3
Hypoxia 0.9 0.9
IgA nephropathy (IgAN) 0.5 0.7 -0.4
Inflammatory Bowel Disease 3.7 4.5 -0.22
Insomnia 1.6 0.7 1.29
Intelligence 0.8 0.1 7
Intracranial aneurysms 0.1 0.1 0
Irritable Bowel Syndrome 2.5 1.3 0.92
ischemic stroke 1.8 1.1 0.64
Liver Cirrhosis 3.4 1.8 0.89
Long COVID 2.3 2.5 -0.09
Low bone mineral density 0.4 -0.4
Lung Cancer 0.6 0.6 0
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 0.9 0.3 2
ME/CFS with IBS 0.3 1.7 -4.67
ME/CFS without IBS 0.6 1.8 -2
membranous nephropathy 0.3 0.3
Menopause 1.1 0.2 4.5
Metabolic Syndrome 2.9 3 -0.03
Mood Disorders 3.6 3.7 -0.03
multiple chemical sensitivity [MCS] 1 1
Multiple Sclerosis 3.8 2.7 0.41
Multiple system atrophy (MSA) 0.3 0.2 0.5
myasthenia gravis 0.9 0.2 3.5
neuropathic pain 0 0.7 0
Neuropathy (all types) 0.3 0.7 -1.33
neuropsychiatric disorders (PANDAS, PANS) 0.9 0.9
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.4 1.9 0.26
NonCeliac Gluten Sensitivity 0.2 0.2 0
Obesity 4.2 2.8 0.5
obsessive-compulsive disorder 2.3 1.6 0.44
Osteoarthritis 1 0.6 0.67
Osteoporosis 0.8 0.9 -0.13
pancreatic cancer 0.3 0.3 0
Parkinson's Disease 3.7 3.3 0.12
Polycystic ovary syndrome 2.7 0.7 2.86
Postural orthostatic tachycardia syndrome 0 0.3 0
Premenstrual dysphoric disorder 0.2 0.1 1
primary biliary cholangitis 0.7 0.3 1.33
Primary sclerosing cholangitis 0.7 1.1 -0.57
Psoriasis 1.7 1.4 0.21
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.4 1.5 1.27
Rosacea 0.3 0.2 0.5
Schizophrenia 1.8 0.6 2
scoliosis 0.8 0 0
sensorineural hearing loss 0.3 0.3
Sjögren syndrome 1.1 1.2 -0.09
Sleep Apnea 1 0.3 2.33
Slow gastric motility / Gastroparesis 0.6 0.2 2
Small Intestinal Bacterial Overgrowth (SIBO) 1 0.6 0.67
Stress / posttraumatic stress disorder 1.8 0.7 1.57
Systemic Lupus Erythematosus 1.2 0.5 1.4
Tic Disorder 0.7 1 -0.43
Tourette syndrome 0.7 0 0
Type 1 Diabetes 1.4 2.2 -0.57
Type 2 Diabetes 3.9 2.7 0.44
Ulcerative colitis 2.8 1.5 0.87
Unhealthy Ageing 1.5 1.2 0.25
Vitiligo 0.6 0.5 0.2

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