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Antiseptic Use: Chlorhexidine is commonly used as a topical antiseptic to clean and disinfect skin before surgery, injections, or other invasive procedures. It helps reduce the risk of infection by killing or inhibiting the growth of microorganisms on the skin.
Dental Applications: Chlorhexidine is used in various dental products such as mouthwashes, gels, and toothpaste to prevent and treat gum diseases like gingivitis and periodontitis. It helps control plaque formation and reduces the number of bacteria in the mouth.
Surgical Scrub: Healthcare professionals use chlorhexidine as a surgical scrub to disinfect their hands and forearms before performing surgery. This helps reduce the risk of surgical site infections.
Catheter Care: Chlorhexidine is sometimes used to clean and disinfect the skin around catheters and other medical devices to prevent infections associated with their use.
Wound Care: Chlorhexidine solutions may be used to clean and irrigate wounds to prevent infection and promote healing.
Vaginal Antiseptic: Chlorhexidine may be used as a vaginal antiseptic to reduce the risk of infection during childbirth or gynecological procedures.
Possible Side Effects: While chlorhexidine is generally considered safe when used as directed, it may cause skin irritation or allergic reactions in some individuals. Prolonged or excessive use of chlorhexidine may also lead to skin dryness or dermatitis. In rare cases, chlorhexidine allergy can manifest as severe allergic reactions, including anaphylaxis.
Oral Discoloration: Long-term use of chlorhexidine mouthwash may cause temporary discoloration of the teeth, tongue, or dental restorations. This staining is usually reversible and can be minimized by proper oral hygiene practices and regular dental cleanings.
Resistance: Prolonged or repeated exposure to chlorhexidine may lead to the development of microbial resistance, reducing its effectiveness over time. It is essential to use chlorhexidine judiciously and rotate with other antiseptics when appropriate to minimize the risk of resistance.
(acipoun, alkanol, anti germ, antiseptol 0.1%, aseptol, baseal, bepanthen plus, bisteryl, buclorhex, bucoral, c-con, cetadine, cetrexidin, cetridine, cetrifarm, chlorhexidine, chlorhexidine 2% in alcohol 10% orion, chlorhexidine 2% in alcohol 70% healthe, chlorhexidine 2% in alcohol 70% orion, chlorhexidine 2% in isopropyl alcohol 70% orion, chlorhexidine 4% healthe, chlorhexidine 5% healthe, chlorhexidine gluconate healthe, chlorhexidine ilsanta, chlorhexidini, chlorhexil colorée, chlorsep, clohex, clorhexil, cmw, colluxid, corsodyl 1%, c-scrub, daxoin, dentisept, dermazyme losham, dermazyme-acti-bac, dermobacter, elugel, ez care, farvicett, hamra blu, hexicon, hexidine, hexigel, hexiprep, hexiprep-t, hexitol 0.125%, hibiscott, indolor, intercept, iteol-3, jiu tai, kou tai, laclorhex, liravlon, mouden, neoxinal alcolico, nitra-hex, obstetric 1% healthe, odontoseptic, oracol, oralon, orasept, oroheks, pantenol plus, pantomed plus, perimex, perio kin, periobacter, pyoderm, r.lens, resichlor, rexadine, rosiseptin, savlo sept, savlon, savlotec, savonol, savrolin, septalor, septéal, sophtal, sorbitocholine, sun vlon, super gold, surgiscrub, sykes animol-c, thiovalone, vita merfen, zordyl, bactigras, chlorhexidine - shyndec pharm, chlorhexidine acetate, chlorhexidine-double-crane pharm, cicajet, klorhexidin, klorhexidin fresenius kabi, medisepta, microgard, neo-cutigenol, neodermovet, nolvasan, novesin wander, privasan, pyoderm s, travahex, uro-tainer chloorhexidinediacetaat, uro-tainer chlorhexidin, 0.02% glucodine w, 0.02% hexizac w, 0.05% glucodine r, 0.05% glucodine w, 0.05% hexizac r, 0.05% hexizac w, 0.1% glucodine r, 0.1% glucodine w, 0.1% hexizac r, 0.1% hexizac w, 0.5% chlorhexidine gluconate tokai, 0.5% glucodine r, 0.5% glucodine w, 0.5% hexizac, 0.5% hexizac n, 0.5% hexizac r, 0.5% hexizac w, 0.5% rapotec, 0.5% rapotec w, 5% chlorhexidine gluconate nichi-iko, 5% chlorhexidine gluconate tokai, 5% chlorhexidine gluconate yakuhan, 5% chlorhexidine yamazen, 5% fermajin, 5% hexizac, 5% hibitane, aakland teatsan plus, aceptik-hc, aceptik-la, acesclean, acnederm, acriflex 0.25%, afresho, alfa red, antisek, antiseptic udder cream, apex surgical, apo-chlorhexidine, asseptic, atoseptal, aviclens, baxedin, baxil, benclosid, benclosid 5%, benclosid v, bepanthen, bepantiseptic, betasept, biguanex, biocanispray, biopatch, biorgasept 0.5%, buccosoin, bucogel, bucoseptil, bucoxidina, bucoxidina ii, c-20, calgodip spray, care chlorhexidine digluconate 0.2%, c-dip, cedium chlorhexidine, cetavlex, cetavlex 0.5%, chemilon, chemiscrub, chloorhexidinedigluconaat fresenius kabi, chloorhexidinegluconaat sage, chloraprep, chloraprep 2%, chloraprep 2%/70%, chloraprep colore, chlorascrub, chlorheksydyny diglukonian sage, chlorhex 3%, chlorhexamed, chlorhexamed 0,1%, chlorhexamed 1%, chlorhexamed direkt 1%, chlorhexamed fluid 0.1%, chlorhexamed forte, chlorhexamed forte 0.2%, chlorhex-c, chlorhexidindigluconat 0.2%, chlorhexidindigluconat 2%, chlorhexidindigluconat sage, chlorhexidindigluconat-lösung, chlorhexidine cetrimide pfizer, chlorhexidine 0.015% cetrimide 0.15% baxter, chlorhexidine 0.5% in alcohol 70% healthe, chlorhexidine 0.5% in alcohol 70% orion, chlorhexidine 1% orion, chlorhexidine 4% orion, chlorhexidine alcoolique gilbert 0.5%, chlorhexidine aqueuse gilbert 0.05%, chlorhexidine aqueuse stérile gilbert 0.2%, chlorhexidine bigluconate biostimulator, chlorhexidine gluconate cetrimide pfizer, chlorhexidine gluconate 0.2%, chlorhexidine gluconate 0.2% healthe, chlorhexidine gluconate 20% yakuhan, chlorhexidine gluconate 4% nichi-iko, chlorhexidine gluconate 4% ory, chlorhexidine gluconate 5% metal, chlorhexidine gluconate ethanol 1% toho, chlorhexidine mybacin, chlorhexidine obstetric, chlorhexidine orion, chlorhexidine pfizer, chlorhexidine sage, chlorhexidine/chlorobutanol arrow, chlorhexidine/chlorobutanol biogaran, chlorhexidine/chlorobutanol eg, chlorhexidine/chlorobutanol mylan, chlorhexidine/chlorobutanol phr lab, chlorhexidine/chlorobutanol ratiopharm, chlorhexidine/chlorobutanol sandoz, chlorhexidine/chlorobutanol teva, chlorhexidine/chlorobutanol zentiva, chlorhex-s, cidegol c, clegen, clegen 0.5% r ebisu, clegen 0.5% w ebisu, clemispray, clobain a, cloder, clorexan, clorexidina e alcool etilico sanitas 0.5%+70%, clorexifarm, clorexyderm, clorexyderm 4%, clorexyderm forte, clorhexidina, clorxil, coditane 5%, colgate, colgate periogard 0.2%, collu-blache, collunovar 0.11%, corsodyl, corsodyl 0.2%, cristalmina, curafil, cuvefilm, dairyclene, debug, delco spray, dental spray gel, dentasep-f, dentodex, dentohexin 0,2%, dentra, deosan, deosan teatcare plus, depanthol, deratin, dermcare pyohex, deroxen, descutan, desinfectol, dettol sterilon, dipklaar, dosiseptine, dosiseptine 0.05%, dyna-hex, dynexan proaktiv chx, ecolab chlorhexidine, ecutan 5%, eczmol 1%, egisept, eimü chlorhexidin-dip, ekuba, elgydium, eludrilperio 0.2%, eludrilpro, emprasan, encident professional, exidine, extinosad, exydina, fectin, fermajin ethanol b, fermajin ethanol w, fermascrub 4%, fordenta, germidal, germisol, germolene, gluchlo, glucodine 0.2%, glucodine 1%, glucodine b ethanol 0.5%, glucodine r ethanol 0.5%, glucodine w ethanol 0.5%, gluconate de chlorhexidine alcoolique gifrer 0.5%, gouttes c.a.p., gynepro antiseptic, h.a.c., hacdil-s, hamra blue, handirub, handiwash, handscrub, hevic 0.5%, hexacon, hexaguard, hexamedal, hexarinse, hexawash, hexene, hexicon nizfarm, hexid, hexident, hexidine e, hexiscrub, hexisept, hexisol, hexitane, hexizac, hexizac 0.2%, hexizac 20%, hexizac al 0.5%, hexizac al 1%, hexodip extra, hibibos g, hibibos t, hibicet, hibideks dap, hibidil, hibidil 0.05%, hibimax, hibiscohol a, hibiscohol a 0.5%, hibiscrub, hibiscrub 4%, hibisoft, hibisoft 0.2%, hibisol, hibistat, hibitane, hibitane 5%, hibitane champ 0.5%, hibitane gluconate 20%, irrisol chloorhexidine, isodril phenylephrine, iwacohol 0.2%, iwacohol 0.5%, iwacohol gl 0.2%, k dip, kenocidin, kevilon, kevirub, klorhex, klorhexidinsprit, klorhexidinsprit fresenius kabi, klorhexol, lifo-scrub, lubimav, marclorhex, maskin, maskin 4%, maskin r, maskin w, masodip, master aid disinfettante, mediscrub, megorex, menalcol reforzado, menalmina, mercryl, mercrylspray, merfen, meridol med chx, meridol perio chlorhexidin 0,2%, merthiolate, metaclor, microbex, microshield, microshield 4%, multi clens, mv chlorhexidine rtu, neo germi-san, neo resiguard, neo-golaseptine, neomercurocromo bianco, neostericlon r, neoxene, neoxene plus, neoxinal, normosept, oradex, oralgene, otodine, otolane, otsol, parmason, paroex 0.12%, peridex, perio-aid, perio-aid con ccp, periochip, periodent, periogard, pervinox clorhexidina, pet dent, plac-out, plak out, plak-out, plurexid 1.5%, prexidine 0.12%, progina, pyohex, pyoskin, qualikin, rapotec, rapotec 5%, ready to use chlorhexidine kilco, reca uberex, rhinadvil tixocortol/chlorhexidine, rivacol, savacol, scanlin, scrubeing 4%, scrubeing s 4%, senospray, septadine, septadine tarhitz, septal, septalone, septéal 0.5%, septidose 0.05%, septivon 1.5%, septofort, simp 80, softasept chx 2%-w/v/70%-v/v, spirytus hibitanowy 0.5% ats, spirytus skazony hibitanem 0.5% amara, spirytus skazony hibitanem 0.5% coel, stafilex, sterets, stericlon, stericlon 0.5%, stericlon 4%, stericlon r, stericlon w, stericlon-r, stericlon-w, summer c-dip, suredip, tarodent, trempex, uiercrème-ace, ultracare teatshield, venture satinex, vetderm, visiodose, vitawund, v-tabur, wellmatch 0.2%, wellup, wellup 0.2%, wellup 0.5%, wellup 1%, xisol, xtragene, ya nuo, ab, ab antitusivo, astrexine, bepanthene plus, bucogerm tos, dentilim 0.1%, freshmel, freshmel tos, mefren, ortoxine, pixidin, rudduck's antiseptic intra-uterine pessary, savior, sebidin, sebidin plus, urogliss-s)
Rank | Probiotic | Impact |
---|---|---|
genus | Bifidobacterium | Reduces |
species | Akkermansia muciniphila | Reduces |
species | Bacteroides uniformis | Reduces |
species | Bifidobacterium adolescentis | Reduces |
species | Bifidobacterium longum | Reduces |
species | Enterococcus faecalis | Reduces |
species | Escherichia coli | Reduces |
species | Lacticaseibacillus paracasei | Reduces |
species | Parabacteroides distasonis | Reduces |
species | Streptococcus thermophilus | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
📓 Direct Citations | 👪👶 Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
3 | 0 | Enterococcus faecalis | species | Decreases |
2 | 0 | Escherichia coli | species | Decreases |
2 | 0 | Fusobacterium nucleatum | species | Decreases |
2 | 0 | Porphyromonas gingivalis | species | Decreases |
2 | 0 | Streptococcus mutans | species | Decreases |
1 | 2 | Streptococcus | genus | Decreases |
1 | 1 | Porphyromonas | genus | Decreases |
1 | 1 | Veillonella | genus | Decreases |
1 | 1 | Veillonella parvula | species | Decreases |
1 | 1 | Streptococcus salivarius | species | Decreases |
1 | 1 | Streptococcus parasanguinis | species | Decreases |
1 | 1 | Streptococcus pneumoniae | species | Decreases |
1 | 1 | Streptococcus sanguinis | species | Decreases |
1 | 0 | Veillonellaceae | family | Decreases |
1 | 0 | Pseudomonas | genus | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.9 | 0.9 | |
Acne | 0.9 | 1.5 | -0.67 |
ADHD | 6.1 | 1.3 | 3.69 |
Age-Related Macular Degeneration and Glaucoma | 1.1 | 0.4 | 1.75 |
Allergic Rhinitis (Hay Fever) | 4.5 | 4.3 | 0.05 |
Allergies | 8.7 | 5 | 0.74 |
Allergy to milk products | 3.1 | 1.7 | 0.82 |
Alopecia (Hair Loss) | 2.2 | 0.6 | 2.67 |
Alzheimer's disease | 8.9 | 9.5 | -0.07 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 4.7 | 2 | 1.35 |
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