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🍽️ isometheptene mucate,(prescription)

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  1. Vasoconstriction: Isometheptene mucate acts as a vasoconstrictor, meaning it causes the narrowing of blood vessels. This effect is thought to contribute to its effectiveness in relieving headaches, particularly migraines, which are often associated with vasodilation and increased blood flow in the brain.

  2. Headache Relief: Isometheptene mucate is used to alleviate the symptoms of various types of headaches, including tension headaches and migraines. By constricting blood vessels, it helps reduce the intensity and frequency of headaches and associated symptoms such as throbbing pain, nausea, and sensitivity to light and sound.

  3. Combination Therapy: Isometheptene mucate is often combined with other medications such as acetaminophen (paracetamol) and dichloralphenazone in products like Midrin or Doralgina. This combination is thought to provide synergistic effects in relieving headaches by targeting different pathways involved in headache pathophysiology.

  4. Migraine Prevention: In some cases, isometheptene mucate may be used as a preventive treatment for migraines, particularly in individuals who experience frequent or severe attacks. By reducing the frequency and severity of migraines, it can improve quality of life and reduce the need for acute headache medications.

  5. Symptomatic Relief: Isometheptene mucate may also provide symptomatic relief for other associated symptoms of headaches, such as nausea, vomiting, and photophobia (sensitivity to light) or phonophobia (sensitivity to sound), although its primary mechanism of action is vasoconstriction.

  6. Rapid Onset of Action: Isometheptene mucate is typically administered orally and is rapidly absorbed into the bloodstream, allowing for relatively quick onset of action. This makes it suitable for acute management of headaches, providing prompt relief of symptoms.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of isometheptene mucate,(prescription) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Anaerobutyricum hallii Reduces
species Bifidobacterium adolescentis Reduces
species Blautia wexlerae Reduces
species Christensenella minuta Reduces
species Enterococcus faecium Reduces
species Lactococcus cremoris Reduces

Bacteria Impacted by isometheptene mucate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Akkermansiaceae family Decreases
0 1 Blautia genus Decreases
0 1 Mediterraneibacter genus Decreases
1 0 Akkermansia genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Streptococcus genus Decreases
0 1 Enterocloster genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Bifidobacterium genus Decreases
0 1 Bacteroides genus Decreases
0 1 environmental samples no rank Decreases
0 1 unclassified Akkermansia no rank Decreases
1 0 Blautia obeum species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Akkermansia muciniphila species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Dorea formicigenerans species Decreases
0 1 Dorea longicatena species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Coprococcus catus species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Coprococcus comes species Decreases
1 0 Streptococcus parasanguinis species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 [Ruminococcus] torques species Decreases
0 1 Blautia liquoris species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 [Clostridium] hylemonae species Decreases
1 0 Enterocloster bolteae species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Lachnoclostridium phocaeense species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Adlercreutzia equolifaciens species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Longicatena caecimuris species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Lactococcus cremoris species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Blautia wexlerae species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Ruminococcus gauvreauii species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Marvinbryantia formatexigens species Decreases
0 1 Solibaculum mannosilyticum species Decreases
0 1 Monoglobus pectinilyticus species Decreases
0 1 Treponema peruense species Decreases
0 1 Streptococcus suis species Decreases
0 1 Adlercreutzia hattorii species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Roseburia hominis species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Eubacterium sp. c-25 species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Parvimonas micra species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Actinomyces oris species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Mogibacterium diversum species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Christensenella minuta species Decreases
0 1 Lawsonibacter asaccharolyticus species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Actinomyces naeslundii species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Flintibacter sp. KGMB00164 species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Enterococcus faecium species Decreases
1 0 Fusobacterium nucleatum species Decreases
0 1 Corynebacterium durum species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Enterococcus cecorum species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Mageeibacillus indolicus species Decreases
0 1 Bacillus paralicheniformis species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Oscillibacter hominis species Decreases
0 1 Romboutsia ilealis species Decreases
0 1 Emergencia timonensis species Decreases
0 1 Ruthenibacterium lactatiformans species Decreases
0 1 Anaerotruncus colihominis species Decreases
0 1 Ruminococcus bovis species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 [Eubacterium] hominis species Decreases
0 1 Clostridioides difficile species Decreases
0 1 Treponema denticola species Decreases
0 1 Faecalibaculum rodentium species Decreases
0 1 Blautia argi species Decreases
0 1 Turicibacter bilis species Decreases
0 1 Clostridium sp. C1 species Decreases
0 1 Roseburia intestinalis species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Chordicoccus furentiruminis species Decreases
0 1 Actinomyces sp. oral taxon 171 species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Phascolarctobacterium succinatutens species Decreases
1 0 Bifidobacterium adolescentis species Decreases
0 1 Akkermansia glycaniphila species Decreases
0 1 Akkermansia massiliensis species Decreases
0 1 Candidatus Akkermansia intestinavium species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases

Impact of isometheptene mucate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0 0
Acne 0 0
ADHD 0.3 0.5 -0.67
Age-Related Macular Degeneration and Glaucoma 0.2 0.2
Allergic Rhinitis (Hay Fever) 1.1 0.8 0.38
Allergies 1.7 0.8 1.13
Allergy to milk products 0.4 0.3 0.33
Alopecia (Hair Loss) 0.2 0.1 1
Alzheimer's disease 1.6 1 0.6
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.7 0.4 0.75
Ankylosing spondylitis 0.6 0.5 0.2
Anorexia Nervosa 0.4 0.4 0
Antiphospholipid syndrome (APS) 0.2 0.2
Asthma 0.5 0.9 -0.8
Atherosclerosis 0.4 0.3 0.33
Atrial fibrillation 0.4 0.1 3
Autism 2.3 1.3 0.77
Autoimmune Disease 0.1 0 0
Barrett esophagus cancer 0.1 0.1 0
benign prostatic hyperplasia 0 0
Biofilm 0.9 0.9
Bipolar Disorder 0 0
Brain Trauma 0.3 0.1 2
Breast Cancer 0.1 0.1
Cancer (General) 0.1 0.2 -1
Carcinoma 0.6 0.3 1
Celiac Disease 0.2 0.5 -1.5
Cerebral Palsy 0.4 0.2 1
Chronic Fatigue Syndrome 1.2 2.1 -0.75
Chronic Kidney Disease 1.1 0.8 0.38
Chronic Lyme 0.1 0 0
Chronic Obstructive Pulmonary Disease (COPD) 0.4 0.2 1
Chronic Urticaria (Hives) 0.1 0.4 -3
Coagulation / Micro clot triggering bacteria 0.1 0.3 -2
Cognitive Function 0.2 0.1 1
Colorectal Cancer 1.5 0.2 6.5
Constipation 0 0.2 0
Coronary artery disease 0.9 0.7 0.29
COVID-19 2 4.1 -1.05
Crohn's Disease 1.4 1.3 0.08
Cushing's Syndrome (hypercortisolism) 0 0
cystic fibrosis 0.4 -0.4
deep vein thrombosis 0.3 0.1 2
Denture Wearers Oral Shifts 0.3 0.3
Depression 1.7 1.9 -0.12
Dermatomyositis 0.1 0 0
Eczema 0.6 0.2 2
Endometriosis 0.4 0.4
Eosinophilic Esophagitis 0.1 0.1 0
Epilepsy 0.8 0.9 -0.13
erectile dysfunction 0.1 0 0
Fibromyalgia 0.4 0.3 0.33
Functional constipation / chronic idiopathic constipation 0.3 0.5 -0.67
gallstone disease (gsd) 0.8 0.3 1.67
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.2 1.2 -5
Generalized anxiety disorder 1.1 0.4 1.75
Glioblastoma 0.1 -0.1
Gout 0.3 0.2 0.5
Graves' disease 0.1 0.6 -5
Gulf War Syndrome 0.3 0.7 -1.33
Halitosis 0.3 0.1 2
Hashimoto's thyroiditis 1.1 0.5 1.2
Heart Failure 0.8 0.8 0
hemorrhagic stroke 0.1 0.1
Hidradenitis Suppurativa 0.2 0.2
High Histamine/low DAO 0 0
hypercholesterolemia (High Cholesterol) 0.5 -0.5
hyperglycemia 0.1 0.9 -8
Hyperlipidemia (High Blood Fats) 0.2 0.2
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 1.2 0.9 0.33
Hypothyroidism 0.2 0.3 -0.5
Hypoxia 0.3 0.3
IgA nephropathy (IgAN) 0.2 0.7 -2.5
Inflammatory Bowel Disease 1.4 2.6 -0.86
Insomnia 0.7 1 -0.43
Intelligence 0 0
Intracranial aneurysms 0.3 0.3
Irritable Bowel Syndrome 1.4 0.8 0.75
ischemic stroke 0.4 0 0
Liver Cirrhosis 0.8 1 -0.25
Long COVID 2.2 1.6 0.38
Low bone mineral density 0.4 -0.4
Lung Cancer 1 -1
Mast Cell Issues / mastitis 0.2 0 0
ME/CFS with IBS 0.3 2 -5.67
ME/CFS without IBS 0.8 0.6 0.33
membranous nephropathy 0.1 0.1
Menopause 0.4 0.2 1
Metabolic Syndrome 1.3 1.7 -0.31
Mood Disorders 2.3 1.3 0.77
multiple chemical sensitivity [MCS] 0.3 0.2 0.5
Multiple Sclerosis 1.4 1 0.4
Multiple system atrophy (MSA) 1 0.3 2.33
myasthenia gravis 0.1 0.1
neuropathic pain 0.4 -0.4
Neuropathy (all types) 0.5 0.5
neuropsychiatric disorders (PANDAS, PANS) 0.1 0.1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.8 1.7 -1.13
NonCeliac Gluten Sensitivity 0.7 0.1 6
Obesity 2.9 2.6 0.12
obsessive-compulsive disorder 1.2 1.5 -0.25
Osteoarthritis 1.3 0.5 1.6
Osteoporosis 0 0.8 0
pancreatic cancer 0.2 0.1 1
Parkinson's Disease 2.2 1.5 0.47
Polycystic ovary syndrome 1.4 0.6 1.33
Postural orthostatic tachycardia syndrome 0 0
Premenstrual dysphoric disorder 0.3 0.3
primary biliary cholangitis 0.1 0.2 -1
Primary sclerosing cholangitis 0.5 1.6 -2.2
Psoriasis 0.9 0.4 1.25
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1.6 0.3 4.33
Rosacea 0.2 0.2
Schizophrenia 1.4 0.5 1.8
scoliosis 0.2 0.2
sensorineural hearing loss 0.5 0.5
Sjögren syndrome 0.3 0.4 -0.33
Sleep Apnea 0.3 0.2 0.5
Slow gastric motility / Gastroparesis 0 0 0
Small Intestinal Bacterial Overgrowth (SIBO) 0.3 0.3
Stress / posttraumatic stress disorder 0.3 0.5 -0.67
Systemic Lupus Erythematosus 0.9 0.5 0.8
Tic Disorder 0.1 0.4 -3
Tourette syndrome 0.3 0 0
Type 1 Diabetes 0.9 0.6 0.5
Type 2 Diabetes 1.7 1.2 0.42
Ulcerative colitis 0.7 1.3 -0.86
Unhealthy Ageing 1.2 0.2 5
Vitiligo 0.2 0.5 -1.5

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