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🍽️ penbutolol sulfate,(prescription)

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  1. Blood Pressure Reduction: Penbutolol sulfate works by blocking the action of certain hormones like adrenaline (epinephrine) on the heart and blood vessels. This results in decreased heart rate and relaxation of blood vessels, leading to lower blood pressure.

  2. Management of Angina: By reducing the workload of the heart and improving blood flow to the heart muscle, penbutolol sulfate can help relieve symptoms of angina, such as chest pain or discomfort.

  3. Heart Rhythm Control: Penbutolol sulfate may also help in controlling abnormal heart rhythms (arrhythmias) by stabilizing the heart's electrical activity.

  4. Side Effects: Common side effects of penbutolol sulfate may include dizziness, fatigue, weakness, nausea, stomach upset, diarrhea, and headache. These side effects are often mild and transient, but if they persist or worsen, it's important to inform your healthcare provider.

  5. Bradycardia (Slow Heart Rate): Since penbutolol sulfate decreases heart rate, it can sometimes lead to bradycardia, especially in individuals with preexisting heart conditions. Symptoms of bradycardia may include fainting, dizziness, fatigue, and shortness of breath. Notify your healthcare provider if you experience these symptoms.

  6. Masking Symptoms of Hypoglycemia: Beta-blockers like penbutolol sulfate can mask some of the signs and symptoms of hypoglycemia (low blood sugar), such as rapid heartbeat and trembling. This may be problematic for individuals with diabetes who rely on these symptoms to recognize low blood sugar levels.

  7. Asthma and COPD: Beta-blockers can potentially worsen respiratory conditions such as asthma or chronic obstructive pulmonary disease (COPD) by narrowing the airways. Penbutolol sulfate should be used with caution in individuals with these conditions and may be contraindicated in some cases.

  8. Fatigue and Exercise Tolerance: Some individuals may experience fatigue or reduced exercise tolerance while taking penbutolol sulfate. This can affect physical activities and performance, so it's essential to discuss any changes in activity level with your healthcare provider.

  9. Interactions with Other Medications: Penbutolol sulfate can interact with other medications, including other blood pressure-lowering drugs, certain antidepressants, and medications for diabetes. It's important to inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

  10. Withdrawal: Abruptly stopping penbutolol sulfate can lead to rebound hypertension or worsening of heart conditions. If discontinuation is necessary, it should be done gradually under the guidance of a healthcare professional.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of penbutolol sulfate,(prescription) On Probiotics

Rank Probiotic Impact
species Faecalibacterium prausnitzii Reduces
species Lacticaseibacillus paracasei Reduces
species Parabacteroides distasonis Reduces

Bacteria Impacted by penbutolol sulfate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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πŸ““ Direct Citations πŸ‘ͺπŸ‘Ά Indirect Citations Taxonomy Rank Effect
0 1 Lachnospira genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Agathobacter genus Decreases
0 1 Streptococcus genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Christensenella genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Wujia genus Decreases
0 1 Simiaoa genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Vescimonas genus Decreases
0 1 Coprococcus genus Decreases
0 1 Roseburia genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Pseudobutyrivibrio genus Decreases
0 1 Acutalibacter genus Decreases
0 1 Wansuia genus Decreases
0 1 Qiania genus Decreases
0 1 Mageeibacillus genus Decreases
0 1 Eubacterium genus Decreases
0 1 Intestinimonas genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Solibaculum genus Decreases
0 1 Oscillibacter genus Decreases
0 1 Anaerotruncus genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Monoglobus genus Decreases
0 1 Intestinibaculum genus Decreases
0 1 Treponema genus Decreases
0 1 Lawsonibacter genus Decreases
0 1 Longicatena genus Decreases
0 1 Dorea genus Decreases
0 1 Faecalibacterium genus Decreases
0 1 Pusillibacter genus Decreases
0 1 Massilistercora genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Ruthenibacterium genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Segatella genus Decreases
1 0 Agathobacter rectalis species Decreases
1 0 Lachnospira eligens species Decreases
1 0 Ruminococcus bromii species Decreases
1 0 Streptococcus salivarius species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Simiaoa sunii species Decreases
0 1 Wujia chipingensis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Roseburia rectibacter species Decreases
0 1 Roseburia hominis species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Coprococcus eutactus species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
0 1 Faecalibacterium sp. I3-3-33 species Decreases
0 1 Roseburia intestinalis species Decreases
0 1 Streptococcus parasanguinis species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 Faecalibacterium sp. IP-1-18 species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Ruminococcus bicirculans (ex Wegman et al. 2014) species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Vescimonas fastidiosa species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Faecalibacterium duncaniae species Decreases
1 0 Parabacteroides merdae species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Faecalibacterium sp. I3-3-89 species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Faecalibacterium sp. I4-3-84 species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Vescimonas coprocola species Decreases
0 1 Coprococcus comes species Decreases
0 1 Faecalibacterium prausnitzii species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Intestinimonas butyriciproducens species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Coprococcus catus species Decreases
0 1 Catenibacterium mitsuokai species Decreases
1 0 Segatella copri species Decreases
1 0 Parabacteroides distasonis species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of penbutolol sulfate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.1 0.1 0
ADHD 1.3 0.6 1.17
Age-Related Macular Degeneration and Glaucoma 0.4 0.1 3
Allergic Rhinitis (Hay Fever) 0.4 0.8 -1
Allergies 0.9 1.7 -0.89
Allergy to milk products 1 0.2 4
Alopecia (Hair Loss) 0.3 0.1 2
Alzheimer's disease 1.4 3.3 -1.36
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.5 0.6 1.5
Ankylosing spondylitis 1.2 1.1 0.09
Anorexia Nervosa 0.8 2.1 -1.63
Antiphospholipid syndrome (APS) 0.4 0.4
Asthma 1.5 0.7 1.14
Atherosclerosis 0.7 0.5 0.4
Atrial fibrillation 2 1.1 0.82
Autism 1.5 3.6 -1.4
Autoimmune Disease 0.2 0.2 0
Barrett esophagus cancer 0.2 -0.2
benign prostatic hyperplasia 0.1 -0.1
Biofilm 0.4 0.4
Bipolar Disorder 0.9 0.9 0
Brain Trauma 0.3 1 -2.33
Cancer (General) 0.2 -0.2
Carcinoma 1.5 1.3 0.15
Celiac Disease 0.5 1.5 -2
Cerebral Palsy 0.3 0.7 -1.33
Chronic Fatigue Syndrome 1.6 2.2 -0.38
Chronic Kidney Disease 0.5 2 -3
Chronic Lyme 0.1 -0.1
Chronic Obstructive Pulmonary Disease (COPD) 1.3 1.1 0.18
Chronic Urticaria (Hives) 0.2 0.3 -0.5
Coagulation / Micro clot triggering bacteria 0.4 1.4 -2.5
Cognitive Function 1.3 0.7 0.86
Colorectal Cancer 1.9 0.8 1.37
Constipation 1 0.2 4
Coronary artery disease 1.3 1.5 -0.15
COVID-19 1.1 4.7 -3.27
Crohn's Disease 2.2 3.8 -0.73
cystic fibrosis 0.2 -0.2
deep vein thrombosis 0.3 1.4 -3.67
Denture Wearers Oral Shifts 0.6 0.6
Depression 2.9 4.4 -0.52
Dermatomyositis 0.2 0.1 1
Eczema 0.4 0.8 -1
Endometriosis 1 1.3 -0.3
Eosinophilic Esophagitis 0.2 -0.2
Epilepsy 0.6 0.4 0.5
erectile dysfunction 0.1 0.1
Fibromyalgia 0.5 0.6 -0.2
Functional constipation / chronic idiopathic constipation 2.1 1.3 0.62
gallstone disease (gsd) 0.9 0.4 1.25
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.1 0.7 -6
Generalized anxiety disorder 0.4 0.6 -0.5
Glioblastoma 0.1 0.3 -2
Gout 0.7 0.1 6
Graves' disease 0.5 1.1 -1.2
Gulf War Syndrome 0.4 0.4
Halitosis 0.4 0.2 1
Hashimoto's thyroiditis 1 0.9 0.11
Heart Failure 2 1.9 0.05
hemorrhagic stroke 0.3 0.3
Hidradenitis Suppurativa 0.7 0.7
High Histamine/low DAO 0.1 0.6 -5
hypercholesterolemia (High Cholesterol) 0.1 -0.1
hyperglycemia 0.6 0.2 2
Hyperlipidemia (High Blood Fats) 0.2 0.1 1
hypertension (High Blood Pressure 2 2.5 -0.25
Hypothyroidism 0.3 0.7 -1.33
Hypoxia 0.3 0.3
IgA nephropathy (IgAN) 0.9 1.1 -0.22
Inflammatory Bowel Disease 1.6 4 -1.5
Insomnia 1.1 1.8 -0.64
Intelligence 0.1 0.6 -5
Intracranial aneurysms 0.8 0.4 1
Irritable Bowel Syndrome 1.6 2.1 -0.31
ischemic stroke 0.8 0.8 0
Juvenile idiopathic arthritis 0.1 -0.1
Liver Cirrhosis 2.8 1.7 0.65
Long COVID 2 4.5 -1.25
Low bone mineral density 1.1 -1.1
Lung Cancer 0.1 0.7 -6
Mast Cell Issues / mastitis 0.2 0.6 -2
ME/CFS with IBS 0.2 0.4 -1
ME/CFS without IBS 0.2 0.3 -0.5
membranous nephropathy 0.2 0.2
Menopause 0.4 0.2 1
Metabolic Syndrome 2.4 2.3 0.04
Mood Disorders 3 3.3 -0.1
multiple chemical sensitivity [MCS] 0.6 0.1 5
Multiple Sclerosis 1.6 2.6 -0.63
Multiple system atrophy (MSA) 0.3 0.5 -0.67
myasthenia gravis 0.3 0.4 -0.33
neuropathic pain 1 -1
Neuropathy (all types) 0.4 0.3 0.33
neuropsychiatric disorders (PANDAS, PANS) 0.2 0.1 1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.8 2.7 -0.5
NonCeliac Gluten Sensitivity 0.1 -0.1
Obesity 3.3 3.6 -0.09
obsessive-compulsive disorder 1.7 1.2 0.42
Osteoarthritis 0.3 1.2 -3
Osteoporosis 0.7 0.6 0.17
pancreatic cancer 0.2 0.2 0
Parkinson's Disease 2.3 3.6 -0.57
Polycystic ovary syndrome 2.2 1.5 0.47
Postural orthostatic tachycardia syndrome 0.1 -0.1
Premenstrual dysphoric disorder 0.1 -0.1
primary biliary cholangitis 0.4 0.3 0.33
Primary sclerosing cholangitis 0.4 1.1 -1.75
Psoriasis 0.8 1.4 -0.75
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3 1.4 1.14
Rosacea 0.5 0.3 0.67
Schizophrenia 1.8 1.6 0.13
scoliosis 0.4 1.1 -1.75
sensorineural hearing loss 0.1 -0.1
Sjögren syndrome 0.7 0.9 -0.29
Sleep Apnea 1 0.4 1.5
Slow gastric motility / Gastroparesis 0.6 0.6
Small Intestinal Bacterial Overgrowth (SIBO) 0.5 0.5
Stress / posttraumatic stress disorder 0.5 0.5 0
Systemic Lupus Erythematosus 0.6 1.3 -1.17
Tic Disorder 0.8 0.5 0.6
Tourette syndrome 0.3 0.3
Type 1 Diabetes 0.9 1.8 -1
Type 2 Diabetes 2.8 2.1 0.33
Ulcerative colitis 1.7 1.7 0
Unhealthy Ageing 0.5 1.4 -1.8
Vitiligo 1.4 0.2 6

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