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🍽️ quinethazone,(prescription)

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  1. Hypertension (High Blood Pressure): Quinethazone is commonly prescribed to manage hypertension. As a diuretic, it works by increasing the excretion of sodium and water by the kidneys, leading to a decrease in blood volume and ultimately lowering blood pressure. By reducing the volume of fluid circulating in the blood vessels, it helps to decrease the workload on the heart and improve blood pressure control.

  2. Edema: Quinethazone is also used to treat edema, which is the abnormal accumulation of fluid in the body's tissues, often manifested as swelling in the legs, feet, ankles, or abdomen. By promoting diuresis, quinethazone helps to remove excess fluid from the body, reducing swelling and relieving symptoms associated with edema.

  3. Congestive Heart Failure: In cases of congestive heart failure, quinethazone may be prescribed as part of a treatment regimen to help reduce fluid retention and alleviate symptoms such as shortness of breath, fatigue, and swelling. By reducing fluid overload, it can help improve cardiac function and overall well-being in individuals with heart failure.

  4. Nephrolithiasis (Kidney Stones): Thiazide diuretics like quinethazone can be used to prevent the formation of certain types of kidney stones by increasing the excretion of calcium in the urine. By reducing urinary calcium concentration, they can help to decrease the risk of stone formation in susceptible individuals.

  5. Diabetes Insipidus: Quinethazone may be used in the management of diabetes insipidus, a condition characterized by excessive urination and thirst due to impaired regulation of fluid balance by the kidneys. By promoting diuresis and reducing urine output, it can help to alleviate symptoms and maintain fluid balance in patients with diabetes insipidus.

  6. Off-label Uses: Quinethazone may also be prescribed off-label for other conditions, such as premenstrual syndrome (PMS), polycystic ovary syndrome (PCOS), and idiopathic hypercalciuria (excessive urinary calcium excretion). However, the evidence supporting its use for these indications may be limited, and its efficacy and safety should be carefully evaluated by a healthcare professional.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of quinethazone,(prescription) On Probiotics

Rank Probiotic Impact
species Anaerobutyricum hallii Reduces
species Christensenella minuta Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Lactococcus cremoris Reduces

Bacteria Impacted by quinethazone,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Lacticaseibacillus genus Decreases
0 1 Coprococcus genus Decreases
0 1 Bilophila genus Decreases
0 1 Subdoligranulum genus Decreases
0 1 Wansuia genus Decreases
0 1 Anaerobutyricum genus Decreases
0 1 Komagataeibacter genus Decreases
0 1 Christensenella genus Decreases
0 1 Lacrimispora genus Decreases
0 1 Butyrivibrio genus Decreases
0 1 Maliibacterium genus Decreases
0 1 Catenibacterium genus Decreases
0 1 Faecalitalea genus Decreases
0 1 Novisyntrophococcus genus Decreases
0 1 Treponema genus Decreases
0 1 Massilistercora genus Decreases
0 1 Eubacterium genus Decreases
0 1 Wujia genus Decreases
0 1 Ligilactobacillus genus Decreases
0 1 Ruminococcus genus Decreases
0 1 Qiania genus Decreases
0 1 Lachnoanaerobaculum genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Chordicoccus genus Decreases
0 1 Escherichia genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Agathobacter genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Coprococcus comes species Decreases
1 0 Bilophila wadsworthia species Decreases
1 0 Phocaeicola vulgatus species Decreases
0 1 Dorea longicatena species Decreases
0 1 Coprococcus catus species Decreases
0 1 Blautia obeum species Decreases
0 1 Dorea formicigenerans species Decreases
0 1 Wansuia hejianensis species Decreases
0 1 Anaerobutyricum hallii species Decreases
0 1 Blautia sp. SC05B48 species Decreases
0 1 Ligilactobacillus ruminis species Decreases
0 1 Subdoligranulum variabile species Decreases
0 1 Fannyhessea vaginae species Decreases
0 1 Komagataeibacter oboediens species Decreases
0 1 Lacrimispora saccharolytica species Decreases
0 1 [Ruminococcus] lactaris species Decreases
0 1 Eubacterium ventriosum species Decreases
0 1 Coprococcus eutactus species Decreases
0 1 Clostridium sp. M62/1 species Decreases
0 1 Lachnoanaerobaculum gingivalis species Decreases
0 1 Blautia liquoris species Decreases
0 1 Christensenella minuta species Decreases
0 1 Clostridium sp. SY8519 species Decreases
0 1 Butyrivibrio crossotus species Decreases
0 1 Coprococcus sp. ART55/1 species Decreases
0 1 Faecalibacterium duncaniae species Decreases
0 1 Catenibacterium mitsuokai species Decreases
0 1 Faecalitalea cylindroides species Decreases
0 1 Massilistercora timonensis species Decreases
0 1 Eubacterium sp. MSJ-33 species Decreases
0 1 Maliibacterium massiliense species Decreases
0 1 Novisyntrophococcus fermenticellae species Decreases
0 1 Treponema peruense species Decreases
0 1 Eubacterium limosum species Decreases
0 1 Catenibacterium sp. co_0103 species Decreases
0 1 Qiania dongpingensis species Decreases
0 1 Faecalibacillus intestinalis species Decreases
0 1 Ruminococcus albus species Decreases
0 1 Eubacterium maltosivorans species Decreases
0 1 Butyrivibrio fibrisolvens species Decreases
0 1 Roseburia hominis species Decreases
0 1 Eubacterium callanderi species Decreases
0 1 Faecalibacterium sp. I2-3-92 species Decreases
0 1 Faecalibacterium sp. I4-1-79 species Decreases
0 1 [Clostridium] hylemonae species Decreases
0 1 Olsenella sp. oral taxon 807 species Decreases
0 1 Ruminococcus champanellensis species Decreases
0 1 Faecalibacterium sp. HTF-F species Decreases
0 1 Intestinibaculum porci species Decreases
0 1 Faecalibacterium sp. IP-3-29 species Decreases
0 1 Anaerostipes hadrus species Decreases
0 1 Pseudobutyrivibrio xylanivorans species Decreases
0 1 Clostridium cadaveris species Decreases
0 1 Phoenicibacter congonensis species Decreases
0 1 Actinomyces naeslundii species Decreases
1 0 Escherichia coli species Decreases
0 1 Lactococcus cremoris species Decreases
1 0 [Ruminococcus] torques species Decreases
1 0 Agathobacter rectalis species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of quinethazone,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.3 0.3
ADHD 0.1 0.7 -6
Age-Related Macular Degeneration and Glaucoma 0.1 0.1
Allergic Rhinitis (Hay Fever) 0.2 0.2 0
Allergies 0.9 0.3 2
Allergy to milk products 0.8 0.2 3
Alopecia (Hair Loss) 0.1 0.1
Alzheimer's disease 0.9 1.1 -0.22
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.5 0.4 0.25
Ankylosing spondylitis 0.2 0.2 0
Anorexia Nervosa 0.1 0.2 -1
Antiphospholipid syndrome (APS) 0.1 0.2 -1
Asthma 0.1 0.1 0
Atherosclerosis 0.2 0.1 1
Atrial fibrillation 0.4 0.4 0
Autism 0.9 1.2 -0.33
Autoimmune Disease 0.1 0.1
benign prostatic hyperplasia 0.1 0.1
Biofilm 0.1 0.1
Bipolar Disorder 0.3 0.4 -0.33
Brain Trauma 0.2 -0.2
Breast Cancer 0.1 0.1
Cancer (General) 0.6 -0.6
Carcinoma 0.8 0.6 0.33
Celiac Disease 0.4 0.4 0
Cerebral Palsy 0.1 -0.1
Chronic Fatigue Syndrome 0.7 2.4 -2.43
Chronic Kidney Disease 0.5 1 -1
Chronic Obstructive Pulmonary Disease (COPD) 0.4 0.4 0
Chronic Urticaria (Hives) 0.2 0.2
Coagulation / Micro clot triggering bacteria 0.3 0.5 -0.67
Cognitive Function 0.2 0.2 0
Colorectal Cancer 1 0.4 1.5
Constipation 0.4 0.4
Coronary artery disease 0.7 0.7 0
COVID-19 1 2 -1
Crohn's Disease 1.4 1.2 0.17
Cushing's Syndrome (hypercortisolism) 0.2 -0.2
cystic fibrosis 0.2 0.2
d-lactic acidosis (one form of brain fog) 0.1 0.1
deep vein thrombosis 0.5 0.5 0
Depression 1.9 2.2 -0.16
Eczema 0.1 0.1 0
Endometriosis 0.5 0.5 0
Epilepsy 0.4 0.2 1
erectile dysfunction 0.1 0.1
Fibromyalgia 0.7 -0.7
Functional constipation / chronic idiopathic constipation 1 0.8 0.25
gallstone disease (gsd) 0.3 0.1 2
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.2 0.5 -1.5
Generalized anxiety disorder 0.4 0.4 0
Glioblastoma 0.1 0.1
Gout 0.1 0.3 -2
Graves' disease 0.1 0.1 0
Gulf War Syndrome 0.3 0.3
Halitosis 0.2 0.2
Hashimoto's thyroiditis 0.5 0.4 0.25
Heart Failure 0.9 0.4 1.25
hemorrhagic stroke 0.1 0.1
Hidradenitis Suppurativa 0.2 0.2
High Histamine/low DAO 0.1 0.1 0
hypercholesterolemia (High Cholesterol) 0.1 0.1
hyperglycemia 0.2 0.2
Hyperlipidemia (High Blood Fats) 0.3 0.3
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 0.6 1 -0.67
Hypothyroidism 0.1 0.6 -5
IgA nephropathy (IgAN) 0.2 0.3 -0.5
Inflammatory Bowel Disease 1.1 1.5 -0.36
Insomnia 0.6 0.1 5
Intelligence 0.4 0.3 0.33
Intracranial aneurysms 0.1 0.4 -3
Irritable Bowel Syndrome 0.7 1 -0.43
ischemic stroke 0.2 0.1 1
Juvenile idiopathic arthritis 0.1 -0.1
Liver Cirrhosis 1.2 1 0.2
Long COVID 1.6 1.6 0
Low bone mineral density 0.6 -0.6
Lung Cancer 0.2 0.3 -0.5
Lymphoma 0.1 0.1
Mast Cell Issues / mastitis 0.1 0.4 -3
ME/CFS with IBS 1.5 -1.5
ME/CFS without IBS 0.2 0.4 -1
Menopause 0.1 0.1 0
Metabolic Syndrome 1.9 1.6 0.19
Mood Disorders 1.8 1.7 0.06
Multiple Sclerosis 0.5 0.7 -0.4
Multiple system atrophy (MSA) 0.1 0.1 0
myasthenia gravis 0.1 0.1 0
neuropathic pain 0.1 -0.1
Neuropathy (all types) 0.1 0.1 0
neuropsychiatric disorders (PANDAS, PANS) 0.1 0.1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.5 1.1 -1.2
Obesity 1.8 1.8 0
obsessive-compulsive disorder 0.9 0.5 0.8
Osteoarthritis 0.4 0.4 0
Osteoporosis 0.2 0.2 0
Parkinson's Disease 1.5 1.1 0.36
Polycystic ovary syndrome 0.9 0.3 2
Postural orthostatic tachycardia syndrome 0.3 -0.3
primary biliary cholangitis 0.1 0.1
Primary sclerosing cholangitis 0.9 -0.9
Psoriasis 0.4 0.3 0.33
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1.2 0.4 2
Rosacea 0.2 0.2
Schizophrenia 0.8 0.5 0.6
scoliosis 0.6 0.3 1
sensorineural hearing loss 0.2 0.2
Sjögren syndrome 0.1 0.2 -1
Sleep Apnea 0.5 0.3 0.67
Slow gastric motility / Gastroparesis 0.3 0.3
Small Intestinal Bacterial Overgrowth (SIBO) 0.5 0.5
Stress / posttraumatic stress disorder 0.2 0.3 -0.5
Systemic Lupus Erythematosus 0.6 0.3 1
Tic Disorder 0.3 0.4 -0.33
Type 1 Diabetes 0.8 0.6 0.33
Type 2 Diabetes 1.9 1.6 0.19
Ulcerative colitis 1 1.2 -0.2
Unhealthy Ageing 0.7 0.6 0.17
Vitiligo 0.2 0.6 -2

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