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Local Anesthesia: Propoxycaine hydrochloride works by blocking nerve signals in a specific area of the body, resulting in temporary loss of sensation. It is commonly used for procedures such as dental work, minor surgeries, and dermatological procedures.
Short-Acting: Propoxycaine hydrochloride is a short-acting local anesthetic, meaning its effects wear off relatively quickly compared to other local anesthetics. This property makes it suitable for brief procedures or when rapid onset and recovery of anesthesia are desired.
Low Systemic Toxicity: When used as directed, propoxycaine hydrochloride typically has low systemic toxicity, meaning it has minimal effects on other parts of the body beyond the area where it is applied. However, like all local anesthetics, it can potentially cause adverse reactions if absorbed into the bloodstream in excessive amounts.
Side Effects: Common side effects associated with the use of propoxycaine hydrochloride may include temporary numbness, tingling, or burning sensation at the site of administration. Rarely, allergic reactions such as rash, itching, or swelling may occur.
Systemic Toxicity: While rare, systemic toxicity can occur if propoxycaine hydrochloride is inadvertently injected into a blood vessel or absorbed in large amounts. Symptoms of systemic toxicity may include dizziness, confusion, seizures, respiratory depression, and cardiovascular collapse. Prompt recognition and treatment of systemic toxicity are essential to prevent serious complications.
Drug Interactions: Propoxycaine hydrochloride may interact with certain medications, such as other local anesthetics or medications that affect the cardiovascular system, increasing the risk of adverse effects. Healthcare providers should be aware of potential drug interactions and adjust dosages accordingly.
Pregnancy and Breastfeeding: The safety of propoxycaine hydrochloride use during pregnancy and breastfeeding has not been well established. Healthcare providers should weigh the potential risks and benefits before administering propoxycaine hydrochloride to pregnant or breastfeeding individuals.
Rank | Probiotic | Impact |
---|---|---|
species | Anaerobutyricum hallii | Reduces |
species | Christensenella minuta | Reduces |
species | Enterococcus faecium | Reduces |
species | Lacticaseibacillus paracasei | Reduces |
species | Lactococcus cremoris | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
π Direct Citations | πͺπΆ Indirect Citations | Taxonomy | Rank | Effect |
---|---|---|---|---|
0 | 1 | Coprococcus | genus | Decreases |
0 | 1 | Lacticaseibacillus | genus | Decreases |
0 | 1 | Parabacteroides | genus | Decreases |
0 | 1 | Roseburia | genus | Decreases |
0 | 1 | Ruminococcus | genus | Decreases |
0 | 1 | Eggerthella | genus | Decreases |
1 | 0 | Coprococcus comes | species | Decreases |
1 | 0 | Lacticaseibacillus paracasei | species | Decreases |
1 | 0 | Parabacteroides merdae | species | Decreases |
0 | 1 | Coprococcus catus | species | Decreases |
0 | 1 | Dorea longicatena | species | Decreases |
0 | 1 | Lactococcus cremoris | species | Decreases |
0 | 1 | Blautia obeum | species | Decreases |
0 | 1 | Streptococcus suis | species | Decreases |
0 | 1 | Dorea formicigenerans | species | Decreases |
0 | 1 | Wansuia hejianensis | species | Decreases |
0 | 1 | Mageeibacillus indolicus | species | Decreases |
0 | 1 | Adlercreutzia equolifaciens | species | Decreases |
0 | 1 | Anaerobutyricum hallii | species | Decreases |
0 | 1 | Chordicoccus furentiruminis | species | Decreases |
0 | 1 | Ligilactobacillus ruminis | species | Decreases |
0 | 1 | Blautia sp. SC05B48 | species | Decreases |
0 | 1 | Adlercreutzia hattorii | species | Decreases |
0 | 1 | Lacrimispora saccharolytica | species | Decreases |
0 | 1 | Subdoligranulum variabile | species | Decreases |
0 | 1 | Fannyhessea vaginae | species | Decreases |
0 | 1 | Butyrivibrio crossotus | species | Decreases |
0 | 1 | [Ruminococcus] lactaris | species | Decreases |
0 | 1 | Komagataeibacter oboediens | species | Decreases |
0 | 1 | Clostridium sp. M62/1 | species | Decreases |
0 | 1 | Eubacterium ventriosum | species | Decreases |
0 | 1 | Bacillus paralicheniformis | species | Decreases |
0 | 1 | Acutalibacter muris | species | Decreases |
0 | 1 | Coprococcus eutactus | species | Decreases |
0 | 1 | Eubacterium sp. c-25 | species | Decreases |
0 | 1 | Clostridium sp. SY8519 | species | Decreases |
0 | 1 | Parvimonas micra | species | Decreases |
0 | 1 | [Ruminococcus] torques | species | Decreases |
0 | 1 | Faecalibaculum rodentium | species | Decreases |
0 | 1 | Lachnoanaerobaculum gingivalis | species | Decreases |
0 | 1 | Enterococcus faecium | species | Decreases |
0 | 1 | Blautia liquoris | species | Decreases |
0 | 1 | Mogibacterium diversum | species | Decreases |
0 | 1 | Coprococcus sp. ART55/1 | species | Decreases |
1 | 0 | Roseburia intestinalis | species | Decreases |
0 | 1 | Christensenella minuta | species | Decreases |
0 | 1 | Faecalibacterium duncaniae | species | Decreases |
0 | 1 | Treponema denticola | species | Decreases |
0 | 1 | Massilistercora timonensis | species | Decreases |
0 | 1 | Actinomyces oris | species | Decreases |
0 | 1 | Eubacterium sp. MSJ-33 | species | Decreases |
0 | 1 | Catenibacterium mitsuokai | species | Decreases |
0 | 1 | Vescimonas fastidiosa | species | Decreases |
0 | 1 | Faecalitalea cylindroides | species | Decreases |
0 | 1 | Roseburia hominis | species | Decreases |
0 | 1 | Roseburia rectibacter | species | Decreases |
0 | 1 | Treponema peruense | species | Decreases |
0 | 1 | Qiania dongpingensis | species | Decreases |
0 | 1 | Novisyntrophococcus fermenticellae | species | Decreases |
0 | 1 | Maliibacterium massiliense | species | Decreases |
0 | 1 | Catenibacterium sp. co_0103 | species | Decreases |
0 | 1 | Pseudobutyrivibrio xylanivorans | species | Decreases |
0 | 1 | Emergencia timonensis | species | Decreases |
0 | 1 | Eubacterium limosum | species | Decreases |
0 | 1 | Faecalibacterium sp. I2-3-92 | species | Decreases |
0 | 1 | Faecalibacterium sp. HTF-F | species | Decreases |
0 | 1 | [Clostridium] hylemonae | species | Decreases |
0 | 1 | Faecalibacterium sp. I4-1-79 | species | Decreases |
0 | 1 | Ruminococcus albus | species | Decreases |
0 | 1 | Phascolarctobacterium sp. Marseille-Q4147 | species | Decreases |
0 | 1 | Corynebacterium durum | species | Decreases |
0 | 1 | Eubacterium maltosivorans | species | Decreases |
0 | 1 | [Eubacterium] hominis | species | Decreases |
0 | 1 | Phascolarctobacterium succinatutens | species | Decreases |
0 | 1 | Faecalibacillus intestinalis | species | Decreases |
0 | 1 | Butyrivibrio fibrisolvens | species | Decreases |
0 | 1 | Intestinibaculum porci | species | Decreases |
0 | 1 | Faecalibacterium sp. IP-3-29 | species | Decreases |
0 | 1 | Eubacterium callanderi | species | Decreases |
0 | 1 | Olsenella sp. oral taxon 807 | species | Decreases |
0 | 1 | Ruminococcus champanellensis | species | Decreases |
0 | 1 | Butyricicoccus sp. GAM44 | species | Decreases |
0 | 1 | Wujia chipingensis | species | Decreases |
0 | 1 | Anaerostipes hadrus | species | Decreases |
0 | 1 | Clostridium cadaveris | species | Decreases |
0 | 1 | Ruthenibacterium lactatiformans | species | Decreases |
0 | 1 | Faecalibacterium sp. I3-3-89 | species | Decreases |
0 | 1 | Phoenicibacter congonensis | species | Decreases |
0 | 1 | Longicatena caecimuris | species | Decreases |
0 | 1 | Marvinbryantia formatexigens | species | Decreases |
0 | 1 | Actinomyces naeslundii | species | Decreases |
0 | 1 | Vescimonas coprocola | species | Decreases |
0 | 1 | Lachnoclostridium phocaeense | species | Decreases |
0 | 1 | Ruminococcus bicirculans (ex Wegman et al. 2014) | species | Decreases |
0 | 1 | Faecalibacterium sp. IP-1-18 | species | Decreases |
0 | 1 | Lawsonibacter asaccharolyticus | species | Decreases |
0 | 1 | Faecalibacterium sp. I4-3-84 | species | Decreases |
0 | 1 | Alistipes ihumii | species | Decreases |
0 | 1 | Streptococcus sanguinis | species | Decreases |
0 | 1 | Clostridium sp. C1 | species | Decreases |
0 | 1 | Alistipes indistinctus | species | Decreases |
0 | 1 | Solibaculum mannosilyticum | species | Decreases |
0 | 1 | Monoglobus pectinilyticus | species | Decreases |
0 | 1 | Ruminococcus gauvreauii | species | Decreases |
0 | 1 | Oscillibacter hominis | species | Decreases |
0 | 1 | Rothia dentocariosa | species | Decreases |
0 | 1 | [Clostridium] scindens | species | Decreases |
0 | 1 | uncultured Alistipes sp. | species | Decreases |
1 | 0 | Ruminococcus bromii | species | Decreases |
1 | 0 | Eggerthella lenta | species | Decreases |
0 | 1 | Lacticaseibacillus paracasei subsp. paracasei | subspecies | Decreases |
0 | 1 | Lacticaseibacillus paracasei subsp. tolerans | subspecies | Decreases |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
ADHD | 0.3 | 0.7 | -1.33 |
Age-Related Macular Degeneration and Glaucoma | 0.2 | 0.2 | 0 |
Allergic Rhinitis (Hay Fever) | 0.3 | 0.2 | 0.5 |
Allergies | 0.8 | 0.1 | 7 |
Allergy to milk products | 0.4 | 0.4 | 0 |
Alopecia (Hair Loss) | 0.1 | -0.1 | |
Alzheimer's disease | 0.7 | 1.1 | -0.57 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.3 | 0.2 | 0.5 |
Ankylosing spondylitis | 0 | 0 | |
Anorexia Nervosa | 0.2 | 0.1 | 1 |
Antiphospholipid syndrome (APS) | 0.2 | 0.2 | |
Asthma | 0.1 | 0.1 | 0 |
Atherosclerosis | 0.3 | 0.2 | 0.5 |
Atrial fibrillation | 0.5 | 0.2 | 1.5 |
Autism | 1 | 0.8 | 0.25 |
Autoimmune Disease | 0.1 | -0.1 | |
Biofilm | 0.1 | 0.1 | |
Bipolar Disorder | 0.2 | 0.5 | -1.5 |
Brain Trauma | 0.1 | 0.1 | 0 |
Cancer (General) | 0.7 | -0.7 | |
Carcinoma | 0.2 | 0.2 | 0 |
Celiac Disease | 0.2 | 0.2 | 0 |
Cerebral Palsy | 0.1 | -0.1 | |
Chronic Fatigue Syndrome | 0.8 | 2.4 | -2 |
Chronic Kidney Disease | 0.6 | 0.9 | -0.5 |
Chronic Lyme | 0.1 | -0.1 | |
Chronic Obstructive Pulmonary Disease (COPD) | 0.3 | 0.4 | -0.33 |
Coagulation / Micro clot triggering bacteria | 0.2 | 0.1 | 1 |
Cognitive Function | 0.2 | 0.1 | 1 |
Colorectal Cancer | 0.4 | 0.2 | 1 |
Constipation | 0 | 0.1 | 0 |
Coronary artery disease | 0.2 | 0.7 | -2.5 |
COVID-19 | 1.4 | 2.6 | -0.86 |
Crohn's Disease | 0.8 | 0.8 | 0 |
cystic fibrosis | 0.1 | -0.1 | |
deep vein thrombosis | 0.3 | 0.1 | 2 |
Denture Wearers Oral Shifts | 0.1 | 0.1 | |
Depression | 1.7 | 2.7 | -0.59 |
Endometriosis | 0.5 | 0.4 | 0.25 |
Epilepsy | 0.2 | 0.5 | -1.5 |
Fibromyalgia | 0.8 | 0.7 | 0.14 |
Functional constipation / chronic idiopathic constipation | 0.7 | 0.8 | -0.14 |
gallstone disease (gsd) | 0.4 | 0.1 | 3 |
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.5 | -0.5 | |
Generalized anxiety disorder | 0.3 | 0.3 | 0 |
Gout | 0 | 0.3 | 0 |
Graves' disease | 0.2 | 0.2 | 0 |
Gulf War Syndrome | 0.3 | 0.3 | |
Halitosis | 0.1 | -0.1 | |
Hashimoto's thyroiditis | 0.5 | 0.2 | 1.5 |
Heart Failure | 0.6 | 0.3 | 1 |
hemorrhagic stroke | 0.2 | 0.2 | |
High Histamine/low DAO | 0.1 | 0 | 0 |
hypercholesterolemia (High Cholesterol) | 0.2 | -0.2 | |
hyperglycemia | 0.2 | -0.2 | |
hypertension (High Blood Pressure | 0.7 | 0.6 | 0.17 |
Hypothyroidism | 0.3 | -0.3 | |
Hypoxia | 0.2 | 0.2 | |
IgA nephropathy (IgAN) | 0.2 | 0.2 | 0 |
Inflammatory Bowel Disease | 0.6 | 1.5 | -1.5 |
Insomnia | 0.5 | 0.1 | 4 |
Intelligence | 0.3 | 0.3 | |
Intracranial aneurysms | 0.2 | 0.3 | -0.5 |
Irritable Bowel Syndrome | 0.3 | 0.6 | -1 |
ischemic stroke | 0.2 | 0.1 | 1 |
Liver Cirrhosis | 0.8 | 0.4 | 1 |
Long COVID | 1.3 | 1.2 | 0.08 |
Low bone mineral density | 0.7 | -0.7 | |
Lung Cancer | 0.2 | -0.2 | |
Mast Cell Issues / mastitis | 0.4 | -0.4 | |
ME/CFS with IBS | 1.7 | -1.7 | |
ME/CFS without IBS | 0.4 | 0.4 | 0 |
Menopause | 0.2 | 0.2 | 0 |
Metabolic Syndrome | 0.8 | 1.1 | -0.38 |
Mood Disorders | 1.8 | 2.2 | -0.22 |
Multiple Sclerosis | 0.5 | 0.9 | -0.8 |
Multiple system atrophy (MSA) | 0.1 | 0 | 0 |
myasthenia gravis | 0.1 | -0.1 | |
neuropathic pain | 0 | 0.4 | 0 |
Neuropathy (all types) | 0 | 0.2 | 0 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.5 | 0.8 | -0.6 |
NonCeliac Gluten Sensitivity | 0 | 0 | |
Obesity | 1.5 | 1.8 | -0.2 |
obsessive-compulsive disorder | 0.8 | 0.5 | 0.6 |
Osteoarthritis | 0.3 | 0.2 | 0.5 |
Osteoporosis | 0.1 | 0.1 | |
Parkinson's Disease | 1.7 | 1.2 | 0.42 |
Polycystic ovary syndrome | 1.2 | 0.2 | 5 |
Postural orthostatic tachycardia syndrome | 0.3 | -0.3 | |
Premenstrual dysphoric disorder | 0.2 | -0.2 | |
Primary sclerosing cholangitis | 0.3 | 1.1 | -2.67 |
Psoriasis | 0.2 | 0.6 | -2 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1.2 | 0.4 | 2 |
Rosacea | 0.2 | 0.1 | 1 |
Schizophrenia | 0.9 | 0.6 | 0.5 |
scoliosis | 0.5 | 0 | 0 |
sensorineural hearing loss | 0.4 | 0.4 | |
Sjögren syndrome | 0.2 | 0.2 | 0 |
Sleep Apnea | 0.4 | 0.4 | 0 |
Slow gastric motility / Gastroparesis | 0 | 0 | |
Small Intestinal Bacterial Overgrowth (SIBO) | 0.5 | 0.5 | |
Stress / posttraumatic stress disorder | 0.2 | 0.6 | -2 |
Systemic Lupus Erythematosus | 0.5 | 0.3 | 0.67 |
Tic Disorder | 0 | 0.3 | 0 |
Type 1 Diabetes | 0.5 | 0.3 | 0.67 |
Type 2 Diabetes | 1 | 0.9 | 0.11 |
Ulcerative colitis | 0.7 | 1.1 | -0.57 |
Unhealthy Ageing | 0.5 | 0.6 | -0.2 |
Vitiligo | 0.2 | 0.8 | -3 |
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