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🍽️ cyproterone acetate,(prescription)

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  1. Antiandrogenic Activity: Cyproterone acetate is known for its antiandrogenic properties, meaning it inhibits the effects of androgens (male hormones) in the body. It competitively blocks the androgen receptor, preventing the binding of testosterone and dihydrotestosterone (DHT) to their receptors. This action reduces the effects of androgens on target tissues and can be beneficial in the treatment of conditions characterized by androgen excess.

  2. Treatment of Hirsutism: Cyproterone acetate is used in the treatment of hirsutism, a condition characterized by excessive hair growth in women, typically in a male-pattern distribution (such as on the face, chest, and back). By blocking androgen receptors and reducing the effects of circulating androgens, cyproterone acetate can help slow down the growth of unwanted facial and body hair in women with hirsutism.

  3. Treatment of Acne: Cyproterone acetate is also used in the treatment of acne vulgaris, particularly in women with hormonal acne or acne that is resistant to conventional therapies. By inhibiting androgen activity, cyproterone acetate helps reduce sebum production, which is a key factor in the development of acne lesions. It is often combined with estrogen-containing oral contraceptives in the treatment of acne to achieve optimal results.

  4. Androgenetic Alopecia: Cyproterone acetate may be used off-label in the treatment of androgenetic alopecia (male-pattern baldness) in women, particularly in cases where excessive androgen levels contribute to hair loss. By blocking androgen receptors and reducing the effects of androgens on hair follicles, cyproterone acetate may help slow down or stabilize hair loss and promote hair regrowth in some individuals.

  5. Treatment of Hyperandrogenism: Cyproterone acetate is also used in the treatment of hyperandrogenism, a condition characterized by elevated levels of androgens in the body. It may be used to manage symptoms associated with conditions such as polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia (CAH), and androgen-secreting tumors. By reducing androgen levels and inhibiting androgen activity, cyproterone acetate helps alleviate symptoms such as hirsutism, acne, and menstrual irregularities associated with hyperandrogenism.

  6. Contraception: In some countries, cyproterone acetate is combined with ethinyl estradiol (a synthetic estrogen) in oral contraceptive pills for birth control purposes. These combination pills provide both contraceptive and antiandrogenic effects, making them useful for women with androgen-related conditions such as hirsutism, acne, or polycystic ovary syndrome (PCOS).

  7. Side Effects: Common side effects of cyproterone acetate may include menstrual irregularities, breast tenderness, nausea, fatigue, and mood changes. Long-term use of cyproterone acetate may be associated with an increased risk of liver toxicity, thromboembolic events (such as blood clots), and depression. Patients should be monitored regularly for side effects during cyproterone acetate therapy, and treatment should be adjusted as needed based on individual response and tolerance.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of cyproterone acetate,(prescription) On Probiotics

Rank Probiotic Impact
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Parabacteroides distasonis Reduces

Bacteria Impacted by cyproterone acetate,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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📓 Direct Citations 👪👶 Indirect Citations Taxonomy Rank Effect
0 1 Escherichia genus Decreases
0 1 Roseburia genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Bacteroides genus Decreases
0 1 Coprococcus genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Phocaeicola genus Decreases
0 1 Streptococcus genus Decreases
0 1 Segatella genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
1 0 Phocaeicola vulgatus species Decreases
1 0 Roseburia intestinalis species Decreases
1 0 Mediterraneibacter gnavus species Decreases
1 0 Coprococcus comes species Decreases
1 0 Parabacteroides distasonis species Decreases
1 0 Segatella copri species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Fusobacterium nucleatum species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Escherichia coli species Decreases
1 0 Streptococcus parasanguinis species Decreases
1 0 Bacteroides caccae species Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of cyproterone acetate,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.4 0.4
Acne 0.6 0.6
ADHD 1.6 0.3 4.33
Age-Related Macular Degeneration and Glaucoma 0.5 0.4 0.25
Allergic Rhinitis (Hay Fever) 2.2 0.6 2.67
Allergies 2.3 1.2 0.92
Allergy to milk products 0.7 1.3 -0.86
Alopecia (Hair Loss) 0.6 0.6
Alzheimer's disease 2.1 3 -0.43
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.1 0.1 10
Ankylosing spondylitis 2.5 1.2 1.08
Anorexia Nervosa 0.7 1.3 -0.86
Antiphospholipid syndrome (APS) 1.5 1.5
Asthma 2 1.1 0.82
Atherosclerosis 0.9 1.9 -1.11
Atrial fibrillation 1.5 1.9 -0.27
Autism 4.8 4.9 -0.02
Autoimmune Disease 0.9 0.5 0.8
Barrett esophagus cancer 0.3 0.3 0
benign prostatic hyperplasia 0.6 0.3 1
Biofilm 1.4 1.4
Bipolar Disorder 1.3 0.8 0.63
Brain Trauma 0.3 0.8 -1.67
Breast Cancer 0.7 0.7
Cancer (General) 0.3 0.5 -0.67
Carcinoma 2.1 0.7 2
Celiac Disease 2.3 0.7 2.29
Cerebral Palsy 0.6 0.8 -0.33
Chronic Fatigue Syndrome 1.7 3 -0.76
Chronic Kidney Disease 2 0.8 1.5
Chronic Lyme 0.8 -0.8
Chronic Obstructive Pulmonary Disease (COPD) 1.3 1.4 -0.08
Chronic Urticaria (Hives) 1 0.8 0.25
Coagulation / Micro clot triggering bacteria 1.4 0.8 0.75
Cognitive Function 1.6 0.8 1
Colorectal Cancer 4.6 1.3 2.54
Constipation 1.6 0.5 2.2
Coronary artery disease 1.7 1.3 0.31
COVID-19 3.4 4.7 -0.38
Crohn's Disease 5.2 2 1.6
Cushing's Syndrome (hypercortisolism) 1 -1
cystic fibrosis 0.7 0.8 -0.14
d-lactic acidosis (one form of brain fog) 0.1 0.1
deep vein thrombosis 2 1.1 0.82
Denture Wearers Oral Shifts 0.7 0.7
Depression 5 4.4 0.14
Dermatomyositis 0.3 0.3
Eczema 1.8 0.7 1.57
Endometriosis 2 1 1
Eosinophilic Esophagitis 0.3 0.3 0
Epilepsy 1.8 1 0.8
erectile dysfunction 1.8 1.8
Fibromyalgia 1.2 1.5 -0.25
Functional constipation / chronic idiopathic constipation 3.6 2.4 0.5
gallstone disease (gsd) 2 0.8 1.5
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.4 0.3 3.67
Generalized anxiety disorder 2.5 1.4 0.79
Glioblastoma 0.3 -0.3
Gout 0.7 0.3 1.33
Graves' disease 0.7 1.4 -1
Gulf War Syndrome 0.6 0.6 0
Halitosis 1.1 0.3 2.67
Hashimoto's thyroiditis 1.3 0.3 3.33
Heart Failure 2.9 0.5 4.8
hemorrhagic stroke 0.7 0.7
Hidradenitis Suppurativa 0.9 0.9
High Histamine/low DAO 0.7 0.7
hypercholesterolemia (High Cholesterol) 0.1 0.1
hyperglycemia 0.9 0.7 0.29
hypertension (High Blood Pressure 1.9 2 -0.05
Hypothyroidism 0.3 -0.3
Hypoxia 1.4 0.6 1.33
IgA nephropathy (IgAN) 1.3 2.2 -0.69
Inflammatory Bowel Disease 4.4 3.9 0.13
Insomnia 1.1 1.1 0
Intelligence 0.7 0.6 0.17
Intracranial aneurysms 1 0.3 2.33
Irritable Bowel Syndrome 3.4 2.5 0.36
ischemic stroke 1.1 1.4 -0.27
Liver Cirrhosis 3.3 1.8 0.83
Long COVID 4.3 2.3 0.87
Low bone mineral density 0.8 -0.8
Lung Cancer 0.7 0.7
Lymphoma 0.6 0.6
Mast Cell Issues / mastitis 1.1 0.3 2.67
ME/CFS with IBS 0.3 0.9 -2
ME/CFS without IBS 0.9 0.9 0
membranous nephropathy 0.3 0.3
Menopause 0.3 0.5 -0.67
Metabolic Syndrome 3.8 3 0.27
Mood Disorders 4.2 3.7 0.14
multiple chemical sensitivity [MCS] 0.5 0.5
Multiple Sclerosis 2.6 3.2 -0.23
Multiple system atrophy (MSA) 0.1 0.1
myasthenia gravis 0.9 0.5 0.8
neuropathic pain 1.3 -1.3
Neuropathy (all types) 0.3 1.6 -4.33
neuropsychiatric disorders (PANDAS, PANS) 0.4 0.4
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 2.7 1.1 1.45
NonCeliac Gluten Sensitivity 0.3 0.3 0
Obesity 4.8 3.9 0.23
obsessive-compulsive disorder 2.6 2.1 0.24
Osteoarthritis 1.8 0.6 2
Osteoporosis 1.4 0.6 1.33
pancreatic cancer 0.5 0.3 0.67
Parkinson's Disease 3 3.8 -0.27
Polycystic ovary syndrome 5.1 1.1 3.64
Postural orthostatic tachycardia syndrome 0.3 -0.3
Premenstrual dysphoric disorder 0.4 -0.4
primary biliary cholangitis 0.3 0.6 -1
Primary sclerosing cholangitis 1.4 2 -0.43
Psoriasis 0.6 2.8 -3.67
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.9 1.6 1.44
Rosacea 0.5 -0.5
Schizophrenia 1.6 1.6 0
scoliosis 0.4 0.4
Sjögren syndrome 1.9 0.7 1.71
Sleep Apnea 0.6 1.1 -0.83
Slow gastric motility / Gastroparesis 0.4 0.4
Small Intestinal Bacterial Overgrowth (SIBO) 1.3 1.3
Stress / posttraumatic stress disorder 1.7 1.6 0.06
Systemic Lupus Erythematosus 3 0.5 5
Tic Disorder 1 0.6 0.67
Tourette syndrome 0.3 0.3 0
Type 1 Diabetes 2.3 1.8 0.28
Type 2 Diabetes 4.7 3.6 0.31
Ulcerative colitis 2.9 3.5 -0.21
Unhealthy Ageing 2.9 1.3 1.23
Vitiligo 1.2 1 0.2

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