Phascolarctobacterium: NCBI 33024, [genus]

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| Phascolarctobacterium| Phascolarctobacterium Del Dot et al. 1994

1. Short-Chain Fatty Acid Production:

   • Phascolarctobacterium is involved in the fermentation of dietary fibers in the colon, producing short-chain fatty acids (SCFAs) as byproducts. SCFAs, such as acetate, propionate, and butyrate, are known to play important roles in gut health.

2. Butyrate Production:

   • Butyrate, in particular, is of interest because it serves as a major energy source for the cells lining the colon. It has anti-inflammatory properties and is associated with maintaining the health of the colonic epithelium.

3. Metabolism of Fermentable Substrates:

   • Phascolarctobacterium species are capable of metabolizing various fermentable substrates, including lactate and succinate. The metabolism of these substrates contributes to the production of SCFAs and other metabolites.

4. Dietary Influence:

   • The abundance and activity of Phascolarctobacterium can be influenced by dietary factors. Diets rich in fiber and plant-based foods provide substrates for the fermentation processes carried out by these bacteria.

5. Associations with Health Conditions:

   • Changes in the abundance of Phascolarctobacterium have been reported in studies of the gut microbiota in various health conditions. Alterations in the relative abundance of this genus have been associated with conditions such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and metabolic disorders. However, the specific roles of Phascolarctobacterium in these conditions are still being investigated.

6. Anti-Inflammatory Effects:

   • The production of butyrate by Phascolarctobacterium and other bacteria has been linked to anti-inflammatory effects in the gut. Butyrate is known to modulate immune responses and promote a balanced inflammatory environment in the colon.

7. Cross-Feeding Interactions:

   • Phascolarctobacterium is involved in cross-feeding interactions within the gut microbiota. This involves the exchange of metabolic byproducts between different bacterial species, contributing to the overall stability and functionality of the microbial community.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Phascolarctobacterium impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.309164434671402	0.5868470072746277	Bilophila	Parent Taxa
0.30132967233657837	0.5568259358406067	Exiguobacterium	Parent Taxa
0.28856417536735535	0.5627425909042358	Butyricimonas	Parent Taxa
0.28304001688957214	0.561190128326416	Vescimonas	Parent Taxa
0.27086812257766724	0.5520908236503601	Simiaoa	Parent Taxa
0.2661120593547821	0.5407301783561707	Pseudoalteromonas	Parent Taxa
0.2546682357788086	0.5745139122009277	Cloacibacterium	Parent Taxa

Other bacteria of the same rank impacting Phascolarctobacterium

R2	Slope	Tax Name	Parent Chart
0.26460152864456177	0.5031829476356506	Bilophila	Parent Taxa