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Porphyromonas: NCBI 836, [genus]

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| Oribaculum| Oribaculum Moore and Moore 1994| Porphyromonas| Porphyromonas Shah and Collins 1988 emend. Kawamura et al. 2015| Porphyromonas Shah and Collins 1988 emend. Wagener et al. 2014| Porphyromonas Shah and Collins 1988 emend. Willems and Collins 1995

  1. Oral Health:

    • Some species of Porphyromonas are part of the normal oral microbiota in humans. However, they are often associated with periodontal diseases, including gingivitis and periodontitis. Porphyromonas gingivalis, in particular, is known for its role in periodontal disease.
  2. Periodontal Diseases:

    • Porphyromonas gingivalis is considered a major pathogen in periodontal diseases. It can contribute to the inflammation of the gums (gingivitis) and the destruction of the supporting structures of the teeth (periodontitis). The bacterium can form biofilms on tooth surfaces and trigger an immune response that leads to tissue damage.
  3. Systemic Health Implications:

    • Some research suggests that the presence of Porphyromonas gingivalis in the oral cavity may be associated with systemic health issues. There have been studies exploring potential links between periodontal diseases and conditions such as cardiovascular disease, diabetes, and adverse pregnancy outcomes. However, the nature of these associations is complex and continues to be an area of research.
  4. Immune System Interactions:

    • Porphyromonas species, particularly Porphyromonas gingivalis, are capable of evading the host immune response and modulating the inflammatory environment. This ability to manipulate the immune system contributes to the chronicity of periodontal infections.
  5. Research and Therapeutic Approaches:

    • Understanding the virulence factors and pathogenic mechanisms of Porphyromonas species is essential for developing strategies to prevent and treat periodontal diseases. Research is ongoing to explore potential therapeutic approaches, including vaccines and targeted antimicrobial agents.

Other Sources for more information:

Legend

Porphyromonas impacts on other bacteria of the same rank

Other bacteria of the same rank impacting Porphyromonas

R2SlopeTax NameParent Chart
0.25088602304458620.524150013923645HoylesellaParent Taxa

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