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Gout

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Common knowledge amoung some professionals (MD and ND):

  1. Vitamin C: Some research suggests that vitamin C might help lower uric acid levels in the blood, which could potentially reduce the risk of gout attacks. However, evidence supporting vitamin C supplementation specifically for gout prevention or management is not definitive.

  2. Cherry Extract or Cherry Juice: Some studies have suggested that consuming cherries or cherry extract might help reduce the frequency of gout attacks by lowering uric acid levels and reducing inflammation. More research is needed to confirm these effects.

  3. Fish Oil/Omega-3 Fatty Acids: Omega-3 supplements containing EPA and DHA have anti-inflammatory properties that might benefit individuals with gout. Some studies suggest that omega-3 fatty acids might help reduce inflammation and the frequency of gout attacks, but evidence is limited.

  4. Probiotics: While there is ongoing research on the role of gut health in various conditions, including gout, the specific impact of probiotics on gout management is not well-established. Some studies suggest that probiotics might influence gut flora and potentially impact inflammation, but more research is needed to determine their specific role in gout.


Bacteria/Taxa

The Studies below identify bacteria. Check if it has already been reviewed.

1 📚
[Coincident gout and bacterial infection].
Nederlands tijdschrift voor geneeskunde (Ned Tijdschr Geneeskd ) Vol: 154 Issue: Pages: A2141 Pub: 2010 ePub: Authors Jacobs JW,van Reekum F
2 📚
[Staphylococcus aureus bacteremia and epidural mass in a patient with tophaceous gout].
Revue medicale de Bruxelles (Rev Med Brux ) Vol: 30 Issue: 3 Pages: 199-202 Pub: 2009 May-Jun ePub: Authors Horeanga A,Chochrad D,Ben Taib NO,Kampouridis S,Roman A
3 📚
Association Between Gut Microbiota and Elevated Serum Urate in Two Independent Cohorts.
Arthritis & rheumatology (Hoboken, N.J.) (Arthritis Rheumatol ) Vol: 74 Issue: 4 Pages: 682-691 Pub: 2022 Apr ePub: 2022 Mar 8 Authors Wei J,Zhang Y,Dalbeth N,Terkeltaub R,Yang T,Wang Y,Yang Z,Li J,Wu Z,Zeng C,Lei G
4 📚
Coexistence of oligo-articular gout and Mycobacterium kansasii joint and bursal infection in a patient with an orthotopic heart transplant.
Clinical and experimental rheumatology (Clin Exp Rheumatol ) Vol: 27 Issue: 5 Pages: 843-5 Pub: 2009 Sep-Oct ePub: Authors Baker JF,Stonecypher M
5 📚
Coexisting polyarticular septic arthritis, gout and pseudogout.
BMJ case reports (BMJ Case Rep ) Vol: 2018 Issue: Pages: Pub: 2018 Oct 28 ePub: 2018 Oct 28 Authors Colaco C,Dotel R
6 📚
Combined effects of MSU crystals injection and high fat-diet feeding on the establishment of a gout model in C57BL/6 mice.
Advances in rheumatology (London, England) (Adv Rheumatol ) Vol: 60 Issue: 1 Pages: 52 Pub: 2020 Nov 4 ePub: 2020 Nov 4 Authors Lin X,Shao T,Wen X,Wang M,Wen C,He Z
7 📚
Combined Signature of the Fecal Microbiome and Metabolome in Patients with Gout.
Frontiers in microbiology (Front Microbiol ) Vol: 8 Issue: Pages: 268 Pub: 2017 ePub: 2017 Feb 21 Authors Shao T,Shao L,Li H,Xie Z,He Z,Wen C
8 📚
Dissecting the causal effect between gut microbiota, DHA, and urate metabolism: A large-scale bidirectional Mendelian randomization.
Frontiers in immunology (Front Immunol ) Vol: 14 Issue: Pages: 1148591 Pub: 2023 ePub: 2023 Mar 30 Authors Hou T,Dai H,Wang Q,Hou Y,Zhang X,Lin H,Wang S,Li M,Zhao Z,Lu J,Xu Y,Chen Y,Gu Y,Zheng J,Wang T,Wang W,Bi Y,Ning G,Xu M
9 📚
Does seasonality of the microbiota contribute to the seasonality of acute gout flare?
Clinical and experimental rheumatology (Clin Exp Rheumatol ) Vol: 40 Issue: 9 Pages: 1793-1800 Pub: 2022 Sep ePub: 2022 Mar 30 Authors Schlesinger N,Brunetti L,Androulakis IP
10 📚
Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout.
Animals : an open access journal from MDPI (Animals (Basel) ) Vol: 10 Issue: 11 Pages: Pub: 2020 Nov 17 ePub: 2020 Nov 17 Authors Xi Y,Huang Y,Li Y,Yan J,Shi Z
11 📚
Gut microbiota mediated the therapeutic efficiency of Simiao decoction in the treatment of gout arthritis mice.
BMC complementary medicine and therapies (BMC Complement Med Ther ) Vol: 23 Issue: 1 Pages: 206 Pub: 2023 Jun 21 ePub: 2023 Jun 21 Authors Lin X,Wang M,He Z,Hao G
12 📚
Investigating the Impact of Gut Microbiota on Gout Through Mendelian Randomization.
Orthopedic research and reviews (Orthop Res Rev ) Vol: 16 Issue: Pages: 125-136 Pub: 2024 ePub: 2024 May 13 Authors Tang C,Li L,Jin X,Wang J,Zou D,Hou Y,Yu X,Wang Z,Jiang H
13 📚
Metagenome-Based Characterization of the Gut Virome Signatures in Patients With Gout.
Journal of medical virology (J Med Virol ) Vol: 97 Issue: 4 Pages: e70336 Pub: 2025 Apr ePub: Authors Huang L,Chen C,Meng J,Yan Q,Luo G,Sha S,Xing Y,Liu C,Xu M,Zhao L,Guo S,Wu X,Chen H,Ma J,You W,Zhang Y,Guo R,Li S,Yao X,Ma W,Kong X,Zhou P,Sun W
14 📚
Pasteurella multocida and gout in the first metatarsophalangeal joint.
Journal of the American Podiatric Medical Association (J Am Podiatr Med Assoc ) Vol: 89 Issue: 6 Pages: 318-20 Pub: 1999 Jun ePub: Authors Shapero C,Fox IM
15 📚
Pasteurella multocida infectious arthritis with acute gout after a cat bite.
The Journal of rheumatology (J Rheumatol ) Vol: 24 Issue: 8 Pages: 1649-52 Pub: 1997 Aug ePub: Authors Butt TS,Khan A,Ahmad A,Khan MA,Parke A,Hill DR
16 📚
Study on the diversity of Bacteroides and Clostridium in patients with primary gout.
Cell biochemistry and biophysics (Cell Biochem Biophys ) Vol: 71 Issue: 2 Pages: 707-15 Pub: 2015 Mar ePub: Authors Xing SC,Meng DM,Chen Y,Jiang G,Liu XS,Li N,Yan YY,Li CG
17 📚
Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism.
Molecular medicine (Cambridge, Mass.) (Mol Med ) Vol: 27 Issue: 1 Pages: 50 Pub: 2021 May 24 ePub: 2021 May 24 Authors Méndez-Salazar EO,Vázquez-Mellado J,Casimiro-Soriguer CS,Dopazo J,Çubuk C,Zamudio-Cuevas Y,Francisco-Balderas A,Martínez-Flores K,Fernández-Torres J,Lozada-Pérez C,Pineda C,Sánchez-González A,Silveira LH,Burguete-García AI,Orbe-Orihuela C,Lagunas-Martínez A,Vazquez-Gomez A,López-Reyes A,Palacios-González B,Martínez-Nava GA
18 📚
The association between Helicobacter pylori infection and the risk for gout in hyperuricemia patients in China - A cross-sectional study.
Gut pathogens (Gut Pathog ) Vol: 16 Issue: 1 Pages: 24 Pub: 2024 Apr 27 ePub: 2024 Apr 27 Authors Chen L,Zhu Y,Huang Y,Shen K,Chen L
19 📚
Treatment of gouty arthritis is associated with restoring the gut microbiota and promoting the production of short-chain fatty acids.
Arthritis research & therapy (Arthritis Res Ther ) Vol: 24 Issue: 1 Pages: 51 Pub: 2022 Feb 19 ePub: 2022 Feb 19 Authors Park HK,Lee SJ

Treatment Substances

The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.

20 📚
A combination of probiotics and whey proteins enhances anti-obesity effects of calcium and dairy products during nutritional energy restriction in aP2-agouti transgenic mice.
The British journal of nutrition (Br J Nutr ) Vol: 113 Issue: 11 Pages: 1689-96 Pub: 2015 Jun 14 ePub: 2015 Apr 14 Authors Yoda K,Sun X,Kawase M,Kubota A,Miyazawa K,Harata G,Hosoda M,Hiramatsu M,He F,Zemel MB
21 📚
Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides.
eLife (Elife ) Vol: 13 Issue: Pages: Pub: 2024 Nov 7 ePub: 2024 Nov 7 Authors Fu Y,Luo XD,Li JZ,Mo QY,Wang X,Zhao Y,Zhang YM,Luo HT,Xia DY,Ma WQ,Chen JY,Wang LH,Deng QY,Ben L,Kashif Saleemi M,Jiang XZ,Chen J,Miao K,Lin ZP,Zhang P,Ye H,Cao QY,Zhu YW,Yang L,Tu Q,Wang W
22 📚
Hypouricaemic effects of yoghurt containing Lactobacillus gasseri PA-3 in patients with hyperuricaemia and/or gout: A randomised, double-blind, placebo-controlled study.
Modern rheumatology (Mod Rheumatol ) Vol: 29 Issue: 1 Pages: 146-150 Pub: 2019 Jan ePub: 2018 Mar 9 Authors Yamanaka H,Taniguchi A,Tsuboi H,Kano H,Asami Y
23 📚
Intestinal toxicity alleviation and efficacy potentiation through therapeutic administration of Lactobacillus paracasei GY-1 in the treatment of gout flares with colchicine.
Food & function (Food Funct ) Vol: 15 Issue: 3 Pages: 1671-1688 Pub: 2024 Feb 5 ePub: 2024 Feb 5 Authors Zeng J,Li Y,Zou Y,Yang Y,Yang T,Zhou Y
24 📚
Lactobacillus acidophilus versus placebo in the symptomatic treatment of irritable bowel syndrome: the LAPIBSS randomized trial.
Cellular and molecular biology (Noisy-le-Grand, France) (Cell Mol Biol (Noisy-le-grand) ) Vol: 63 Issue: 9 Pages: 122-131 Pub: 2017 Sep 30 ePub: 2017 Sep 30 Authors Sadrin S,Sennoune SR,Gout B,Marque S,Moreau J,Grillasca J,Pons O,Maixent JM
25 📚
Oral treatment with Bifidobacterium longum 51A reduced inflammation in a murine experimental model of gout.
Beneficial microbes (Benef Microbes ) Vol: 6 Issue: 6 Pages: 799-806 Pub: 2015 ePub: 2015 Aug 31 Authors Vieira AT,Galvão I,Amaral FA,Teixeira MM,Nicoli JR,Martins FS
26 📚
Probiotic Potential and Safety Evaluation of Enterococcus faecalis OB14 and OB15, Isolated From Traditional Tunisian Testouri Cheese and Rigouta, Using Physiological and Genomic Analysis.
Frontiers in microbiology (Front Microbiol ) Vol: 10 Issue: Pages: 881 Pub: 2019 ePub: 2019 Apr 24 Authors Baccouri O,Boukerb AM,Farhat LB,Zébré A,Zimmermann K,Domann E,Cambronel M,Barreau M,Maillot O,Rincé I,Muller C,Marzouki MN,Feuilloley M,Abidi F,Connil N

Quick Reference

The following items have been cited in the above studies

IDStudiesNameAKA
50 1   bifidobacterium longum {B.Longum } May include Bifidobacterium longum subsp. infantis and Bifidobacterium longum subsp. longum
1756 1   enterococcus faecium {E. faecium} Was Streptococcus faecium, sometimes Enterococcus lactis
241 1   Lacticaseibacillus paracasei {L.paracasei} Was also known as Lactobacillus casei subsp. pseudoplantarum
230 1   lactobacillus acidophilus {L. acidophilus} Bacillus acidophilus
237 1   Lactobacillus gasseri {L.gasseri}
243 1   Lactobacillus plantarum {L. plantarum} lactobacillus plantarum, Lactobacillus arabinosus
247 1   lactobacillus rhamnosus gg l rhamnosus gg (probiotics)

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