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NonCeliac Gluten Sensitivity

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Common knowledge amoung some professionals (MD and ND):

  1. Probiotics: Probiotics are beneficial bacteria that support gut health and may aid in overall digestion. While they may not directly address gluten sensitivity, some people with digestive issues, including those related to NCGS, find that probiotics help alleviate symptoms like bloating, gas, or discomfort.

  2. Digestive Enzymes: Some individuals with gluten sensitivity might try digestive enzyme supplements containing enzymes like DPP-IV, which might assist in breaking down gluten proteins. However, these enzymes are not considered a replacement for a gluten-free diet, and their effectiveness in managing symptoms related to gluten sensitivity is not fully established.

  3. Vitamin and Mineral Supplements: If a person with NCGS has nutrient deficiencies due to malabsorption or dietary restrictions, supplementation with vitamins and minerals (such as B vitamins, iron, calcium, etc.) might be necessary. It's essential to work with a healthcare provider to identify specific deficiencies before starting supplementation.

  4. Probiotic-Rich Foods: Incorporating natural probiotics from fermented foods like yogurt, kefir, sauerkraut, or kimchi might support a healthy gut microbiome. These foods can potentially aid in digestive health but should be consumed cautiously if they contain gluten.

  5. Gut Health Supplements: Some individuals find that supplements containing ingredients like glutamine, fiber, or certain herbs promote gut health and comfort. However, their specific impact on NCGS is not well-documented.


Bacteria/Taxa

The Studies below identify bacteria. Check if it has already been reviewed.

1 ๐Ÿ“š
Comparison of gut microbiota profile in celiac disease, non-celiac gluten sensitivity and irritable bowel syndrome: A systematic review.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology (Turk J Gastroenterol ) Vol: 31 Issue: 11 Pages: 735-745 Pub: 2020 Nov ePub: Authors Transeth EL,Dale HF,Lied GA
2 ๐Ÿ“š
Diet, Perceived Intestinal Well-Being and Compositions of Fecal Microbiota and Short Chain Fatty Acids in Oat-Using Subjects with Celiac Disease or Gluten Sensitivity.
Nutrients (Nutrients ) Vol: 12 Issue: 9 Pages: Pub: 2020 Aug 25 ePub: 2020 Aug 25 Authors Nylund L,Hakkola S,Lahti L,Salminen S,Kalliomรคki M,Yang B,Linderborg KM
3 ๐Ÿ“š
First Insights into the Gut Microbiota of Mexican Patients with Celiac Disease and Non-Celiac Gluten Sensitivity.
Nutrients (Nutrients ) Vol: 10 Issue: 11 Pages: Pub: 2018 Nov 2 ePub: 2018 Nov 2 Authors Garcia-Mazcorro JF,Rivera-Gutierrez X,Cobos-Quevedo OJ,Grube-Pagola P,Meixueiro-Daza A,Hernandez-Flores K,Cabrera-Jorge FJ,Vivanco-Cid H,Dowd SE,Remes-Troche JM
4 ๐Ÿ“š
Influence of low FODMAP and gluten-free diets on disease activity and intestinal microbiota in patients with non-celiac gluten sensitivity.
Clinical nutrition (Edinburgh, Scotland) (Clin Nutr ) Vol: 38 Issue: 2 Pages: 697-707 Pub: 2019 Apr ePub: 2018 Apr 4 Authors Dieterich W,Schuppan D,Schink M,Schwappacher R,Wirtz S,Agaimy A,Neurath MF,Zopf Y
5 ๐Ÿ“š
Lack of Effect of Gluten Challenge on Fecal Microbiome in Patients With Celiac Disease and Non-Celiac Gluten Sensitivity.
Clinical and translational gastroenterology (Clin Transl Gastroenterol ) Vol: 12 Issue: 12 Pages: e00441 Pub: 2021 Dec 20 ePub: 2021 Dec 20 Authors Nobel YR,Rozenberg F,Park H,Freedberg DE,Blaser MJ,Green PHR,Uhlemann AC,Lebwohl B
6 ๐Ÿ“š
Non-Celiac Gluten/Wheat Sensitivity: Clinical Characteristics and Microbiota and Mycobiota Composition by Response to the Gluten Challenge Test.
Nutrients (Nutrients ) Vol: 13 Issue: 4 Pages: Pub: 2021 Apr 12 ePub: 2021 Apr 12 Authors Ponzo V,Ferrocino I,Goitre I,Pellegrini M,Bruno M,Astegiano M,Cadario G,Castellana E,Bioletto F,Corvaglia MR,Malfa P,Cocolin L,Ghigo E,Bo S
7 ๐Ÿ“š
The role of microbiome in the development of gluten-related disorders.
Best practice & research. Clinical gastroenterology (Best Pract Res Clin Gastroenterol ) Vol: 72 Issue: Pages: 101951 Pub: 2024 Sep ePub: 2024 Sep 5 Authors Catassi G,Lener E,Grattagliano MM,Motuz S,Zavarella MA,Bibbรฒ S,Cammarota G,Gasbarrini A,Ianiro G,Catassi C

Treatment Substances

The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.

8 ๐Ÿ“š
Fermentation of Gluten by Lactococcus lactis LLGKC18 Reduces its Antigenicity and Allergenicity.
Probiotics and antimicrobial proteins (Probiotics Antimicrob Proteins ) Vol: 14 Issue: 5 Pages: 779-791 Pub: 2022 Oct ePub: 2021 Jun 3 Authors El Mecherfi KE,Lupi R,Cherkaoui M,Albuquerque MAC,Todorov SD,Tranquet O,Klingebiel C,Rogniaux H,Denery-Papini S,Onno B,de Melo Franco BDG,Larrรฉ C
9 ๐Ÿ“š
Identification and characterization of intestinal lactobacilli strains capable of degrading immunotoxic peptides present in gluten.
Journal of applied microbiology (J Appl Microbiol ) Vol: 118 Issue: 2 Pages: 515-27 Pub: 2015 Feb ePub: 2014 Dec 18 Authors Duar RM,Clark KJ,Patil PB,Hernรกndez C,Brรผning S,Burkey TE,Madayiputhiya N,Taylor SL,Walter J

Quick Reference

The following items have been cited in the above studies

IDStudiesNameAKA
3144 1   Lactobacillus Johnsonii {Lactobacillus Johnsonii} Taxonomy ID: 33959
3185 1   Lactococcus lactis {Streptococcus lactis}
248 1   Ligilactobacillus salivarius {L. salivarius} lactobacillus salivarius

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