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Common knowledge amoung some professionals (MD and ND):
Probiotics: Research into the gut-brain connection suggests a potential link between gut health and mental health. Some studies indicate that probiotics might have a role in modulating mood and reducing anxiety. While this area of research is evolving, more studies are needed to understand the specific effects of probiotics on OCD symptoms.
N-Acetylcysteine (NAC): Some limited studies suggest that NAC, a compound that acts as a precursor to glutathione (an antioxidant), might have potential benefits in reducing OCD symptoms in some individuals. However, further research is needed to establish its effectiveness, dosage, and long-term safety for OCD treatment.
Omega-3 Fatty Acids: Omega-3 fatty acids found in fish oil might have some potential benefits for mental health and mood regulation. Some individuals with mental health conditions, including OCD, might explore omega-3 supplementation, although evidence specific to OCD is limited.
Inositol: Inositol, a compound similar to glucose, has been studied for its potential in managing OCD symptoms. Some research suggests that high doses of inositol might have benefits in reducing OCD symptoms. However, more research is needed to determine its effectiveness and appropriate dosages.
The Studies below identify bacteria. Check if it has already been reviewed.
| 1 | 📚 |
Basal metabolic rate mediates the causal relationship between gut microbiota and osteoarthritis: a two-step bidirectional Mendelian randomization study.
Frontiers in microbiology (Front Microbiol ) Vol: 15 Issue: Pages: 1371679 Pub: 2024 ePub: 2024 Oct 1 Authors Li J,Liang J,Liu Y,Sun W,Sun W |
| 2 | 📚 |
Brucella osteoarthritis: recent progress and future directions.
Frontiers in microbiology (Front Microbiol ) Vol: 16 Issue: Pages: 1522537 Pub: 2025 ePub: 2025 Feb 4 Authors Chen J,Zhi F,Zhao G,Su M,Geng H,Song W,Chu Y,Zhang H |
| 3 | 📚 |
Characterizations of the Gut Bacteriome, Mycobiome, and Virome in Patients with Osteoarthritis.
Microbiology spectrum (Microbiol Spectr ) Vol: 11 Issue: 1 Pages: e0171122 Pub: 2023 Feb 14 ePub: 2022 Dec 14 Authors Chen C,Zhang Y,Yao X,Li S,Wang G,Huang Y,Yang Y,Zhang A,Liu C,Zhu D,Li H,Yan Q,Ma W |
| 4 | 📚 |
Clinical Utility of a Multiplex PCR Panel (BioFire Joint Infection(®)) in the Adjustment of Empiric Antimicrobial Therapy: Experience in Pediatric Osteoarticular Infections.
Children (Basel, Switzerland) (Children (Basel) ) Vol: 11 Issue: 10 Pages: Pub: 2024 Oct 14 ePub: 2024 Oct 14 Authors Udaondo C,Alcobendas Rueda RM,Diaz-Delgado B,Remesal A,Quiles-Melero I,Calvo C |
| 5 | 📚 |
Diet influences knee osteoarthritis osteophyte formation via gut microbiota and serum metabolites.
iScience (iScience ) Vol: 27 Issue: 6 Pages: 110111 Pub: 2024 Jun 21 ePub: 2024 May 24 Authors Zhu D,Wang X,Xi Z,Chen K,Feng Y,Zi C,Pan Z,Ma X,Zeng X,Feng H,Guo D |
| 6 | 📚 |
Dysbiosis of the gut microbiome is a risk factor for osteoarthritis in older female adults: a case control study.
BMC bioinformatics (BMC Bioinformatics ) Vol: 22 Issue: 1 Pages: 299 Pub: 2021 Jun 3 ePub: 2021 Jun 3 Authors Chen J,Wang A,Wang Q |
| 7 | 📚 |
Exploring associations among pro-inflammatory cytokines, osteoarthritis, and gut microbiome composition in individuals with obesity using machine learning.
Osteoarthritis and cartilage open (Osteoarthr Cartil Open ) Vol: 7 Issue: 2 Pages: 100603 Pub: 2025 Jun ePub: 2025 Mar 19 Authors Kurz C,Arbeeva L,Azcarate-Peril MA,Stewart DA,Lascelles BDX,Loeser RF,Nelson AE |
| 8 | 📚 |
Genetic association of gut microbiota with osteoarthritis: a multivariable Mendelian randomization study considering medication use.
Journal of medical microbiology (J Med Microbiol ) Vol: 73 Issue: 10 Pages: Pub: 2024 Oct ePub: Authors Huang MH,Liu CX,Huang YS,He TY,Dong ZQ |
| 9 | 📚 |
Gut microbial dysbiosis is associated with allergen-specific IgE responses in young children with airway allergies.
The World Allergy Organization journal (World Allergy Organ J ) Vol: 12 Issue: 3 Pages: 100021 Pub: 2019 ePub: 2019 Mar 25 Authors Chiu CY,Chan YL,Tsai MH,Wang CJ,Chiang MH,Chiu CC |
| 10 | 📚 |
Integrated Multi-Omics Analyses Reveal Lipid Metabolic Signature in Osteoarthritis.
Journal of molecular biology (J Mol Biol ) Vol: 437 Issue: 6 Pages: 168888 Pub: 2025 Mar 15 ePub: 2024 Dec 4 Authors Wang Y,Zeng T,Tang D,Cui H,Wan Y,Tang H |
| 11 | 📚 |
Intestinal Dysbiosis Featuring Abundance of Ruminococcus gnavus Associates With Allergic Diseases in Infants.
Gastroenterology (Gastroenterology ) Vol: 154 Issue: 1 Pages: 154-167 Pub: 2018 Jan ePub: 2017 Sep 12 Authors Chua HH,Chou HC,Tung YL,Chiang BL,Liao CC,Liu HH,Ni YH |
| 12 | 📚 |
Intestinal microbiome composition and its relation to joint pain and inflammation.
Nature communications (Nat Commun ) Vol: 10 Issue: 1 Pages: 4881 Pub: 2019 Oct 25 ePub: 2019 Oct 25 Authors Boer CG,Radjabzadeh D,Medina-Gomez C,Garmaeva S,Schiphof D,Arp P,Koet T,Kurilshikov A,Fu J,Ikram MA,Bierma-Zeinstra S,Uitterlinden AG,Kraaij R,Zhernakova A,van Meurs JBJ |
| 13 | 📚 |
The Role of MicroRNAs in the Pathophysiology of Osteoarthritis.
International journal of molecular sciences (Int J Mol Sci ) Vol: 25 Issue: 12 Pages: Pub: 2024 Jun 8 ePub: 2024 Jun 8 Authors Szala D,Kopanska M,Trojniak J,Jablonski J,Hanf-Osetek D,Snela S,Zawlik I |
The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.
| 14 | 📚 |
Combinatmarion treatment with Lactobacillus acidophilus LA-1, vitamin B, and curcumin ameliorates the progression of osteoarthritis by inhibiting the pro-inflammatory mediators.
Immunology letters (Immunol Lett ) Vol: 228 Issue: Pages: 112-121 Pub: 2020 Dec ePub: 2020 Nov 1 Authors Jhun J,Min HK,Na HS,Kwon JY,Ryu J,Cho KH,Choi J,Jung K,Lee SY,Kim SJ,Yang CW,Park SH,Cho ML |
| 15 | 📚 |
Effectiveness of new selenium-enriched mutated probiotics in reducing inflammatory effects of piroxicam medication in liver and kidney.
Inflammopharmacology (Inflammopharmacology ) Vol: 30 Issue: 6 Pages: 2097-2106 Pub: 2022 Dec ePub: 2022 Sep 9 Authors Darwish AM,Khattab AEA,Abd El-Razik KA,Othman SI,Allam AA,Abu-Taweel GM |
| 16 | 📚 |
Latilactobacillus sakei LB-P12 Ameliorates Osteoarthritis by Reducing Cartilage Degradation and Inflammation via Regulation of NF-?B/HIF-2a Pathway.
Journal of microbiology and biotechnology (J Microbiol Biotechnol ) Vol: 35 Issue: Pages: e2504013 Pub: 2025 May 2 ePub: 2025 May 2 Authors Song M,Kim WJ,Shim J,Song K |
| 17 | 📚 |
Live and Dead Clostridium butyricum GKB7 Diminish Osteoarthritis Pain and Progression in Preclinical Animal Model.
Environmental toxicology (Environ Toxicol ) Vol: 39 Issue: 11 Pages: 4927-4935 Pub: 2024 Nov ePub: 2024 Jun 25 Authors Chen LC,Lin YY,Tsai YS,Chen CC,Chang TC,Chen HT,Hsu CJ,Tang CH |
| 18 | 📚 |
Membrane vesicles from Lactobacillus johnsonii delay osteoarthritis progression via modulating macrophage glutamine synthetase/mTORC1 axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (Biomed Pharmacother ) Vol: 165 Issue: Pages: 115204 Pub: 2023 Sep ePub: 2023 Jul 25 Authors Liu R,Zhou Y,Chen H,Xu H,Zuo M,Chen B,Wang H |
| 19 | 📚 |
Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis.
iScience (iScience ) Vol: 26 Issue: 9 Pages: 107647 Pub: 2023 Sep 15 ePub: 2023 Aug 15 Authors Hou L,Wang G,Zhang X,Lu F,Xu J,Guo Z,Lin J,Zheng Z,Liu H,Hou Y,Sun K,Guo F |
| 20 | 📚 |
Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by improving fecal microbiome metabolism and enhancing the colonic barrier.
Frontiers in microbiology (Front Microbiol ) Vol: 13 Issue: Pages: 1005842 Pub: 2022 ePub: 2022 Nov 10 Authors Tang J,Song X,Zhao M,Chen H,Wang Y,Zhao B,Yu S,Ma T,Gao L |
| 21 | 📚 |
Probiotics for pain of osteoarthritis; An N-of-1 trial of individual effects.
Complementary therapies in medicine (Complement Ther Med ) Vol: 54 Issue: Pages: 102548 Pub: 2020 Nov ePub: 2020 Aug 29 Authors Taye I,Bradbury J,Grace S,Avila C |
| 22 | 📚 |
Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice.
Calcified tissue international (Calcif Tissue Int ) Vol: Issue: Pages: Pub: 2022 Oct 19 ePub: 2022 Oct 19 Authors Sophocleous A,Azfer A,Huesa C,Stylianou E,Ralston SH |
| 23 | 📚 |
Safflower Seed Extract Attenuates the Development of Osteoarthritis by Blocking NF-?B Signaling.
Pharmaceuticals (Basel, Switzerland) (Pharmaceuticals (Basel) ) Vol: 14 Issue: 3 Pages: Pub: 2021 Mar 12 ePub: 2021 Mar 12 Authors Han SJ,Lim MJ,Lee KM,Oh E,Shin YS,Kim S,Kim JS,Yun SP,Kang LJ |
| 24 | 📚 |
The effect of probiotic Lactobacillus casei Shirota on knee osteoarthritis: a randomised double-blind, placebo-controlled clinical trial.
Beneficial microbes (Benef Microbes ) Vol: 8 Issue: 5 Pages: 697-703 Pub: 2017 Oct 13 ePub: 2017 Jul 20 Authors Lei M,Guo C,Wang D,Zhang C,Hua L |
| 25 | 📚 |
The Effect of Probiotics on the Management of Pain and Inflammation in Osteoarthritis: A Systematic Review and Meta-Analysis of Clinical Studies.
Nutrients (Nutrients ) Vol: 16 Issue: 14 Pages: Pub: 2024 Jul 12 ePub: 2024 Jul 12 Authors Moyseos M,Michael J,Ferreira N,Sophocleous A |
| 26 | 📚 |
The efficacy of Nigella sativa L. oil on serum biomarkers of inflammation and oxidative stress and quality of life in patients with knee osteoarthritis: A parallel triple-arm double-blind randomized controlled trial.
Food science & nutrition (Food Sci Nutr ) Vol: 11 Issue: 12 Pages: 7910-7920 Pub: 2023 Dec ePub: 2023 Oct 7 Authors Amirtaheri Afshar A,Toopchizadeh V,Dolatkhah N,Jahanjou F,Farshbaf-Khalili A |
| 27 | 📚 |
The Oral Administration of Lactobacillus delbrueckii subsp. lactis 557 (LDL557) Ameliorates the Progression of Monosodium Iodoacetate-Induced Osteoarthritis.
Current issues in molecular biology (Curr Issues Mol Biol ) Vol: 46 Issue: 8 Pages: 8969-8980 Pub: 2024 Aug 16 ePub: 2024 Aug 16 Authors Huang LW,Huang TC,Hu YC,Hsieh BS,Lin JS,Hsu HY,Lee CC,Chang KL |
The following items have been cited in the above studies
| ID | Studies | Name | AKA |
|---|---|---|---|
| 1876 | 1 | arthamus tinctorius {Safflower} | False saffron |
| 32 | 1 | bacillus subtilis {B.Subtilis } | Hay bacillus, grass bacillus,Vibrio subtilis |
| 46 | 1 | Bifidobacterium animalis subsp. lactis {B. Lactis} | Includes BB-12, DN-173 010 ,Bifidobacterium Regularis,Bifidus Regularis |
| 2980 | 1 | Coenzyme Q10 {CoQ 10} | Ubiquinone,Ubidecarenone,Vitamin Q10,Mitoquinone |
| 234 | 1 | Lacticaseibacillus casei {L. casei} | Streptobacterium casei,Lactobacillus casei |
| 241 | 1 | Lacticaseibacillus paracasei {L.paracasei} | Was also known as Lactobacillus casei subsp. pseudoplantarum |
| 235 | 1 | Lacticaseibacillus paracasei shirota {Yakult} | LcS |
| 230 | 1 | lactobacillus acidophilus {L. acidophilus} | Bacillus acidophilus |
| 238 | 1 | lactobacillus helveticus,lactobacillus rhamnosus | l helveticus,l rhamnosus (probiotics) |
| 3144 | 1 | Lactobacillus Johnsonii {Lactobacillus Johnsonii} | Taxonomy ID: 33959 |
| 3185 | 1 | Lactococcus lactis {Streptococcus lactis} | |
| 1773 | 1 | Latilactobacillus sakei {Lactobacillus sakei} | Lactobacillus bavaricus |
| 1719 | 1 | Nigella sativa {black cumin} | black seed, black caraway, kalonji,fennel flower |
| 1199 | 1 | piroxicam,(prescription) | (abxicam, agomove, aksocam, an er ke, anarom, anartrit, anmatic, ansilin, antiflog, apo piroxicam, apo-piroxicam, arthrosyl, artrilase, artroxicam, arudein, atidem, axcel piroxicam, axicam, baxo, baxo 0.5%, benisan, bicaen, bleduran, brexidol, brexin, brexivel, brionot, brucam, bruxicam, buta rut b12, campain, camrox, camsun, cantor, chemmart piroxicam, clevian, conzila, cp-pirox, cuntong, dispercam, dispercam 0.5%, doloage, dolocare, dolodil, dolokam, dololup, dolonex, enton, erazon, exipan, fabudol, facicam, felcam, felcon, feldco, feldegel, feldemin, felden, felden 0.5%, felden quick-solve, feldene, feldène, feldene 0.5%, feldene fast, feldene flas, feldene gel, feldene-d, feldenedi, feldoral, feldox, felon, fenxicam, finalgel, fines, flamalit, flamic, flexar, flexicam, flexicamin, flodol, flogiatrin, flogiatrin forte, flogostil, focus, foglugen, foldcam, furokan, geldène, geldène 0.5%, goodgen, grazeo, hotemin, ifemed, improntal, infeld, inflacam, inflacam 0.5%, inflaced, inflamene, inflanan, inflax, ipsoflog, ji ke, jiwei, keneton, ketolin, kifadene, kinski, kinskidol, konshien, lampoflex, lanareuma, lenotac, liang ke, licofel, lirocam, lisedema, lubor, luboreta, luo lin, macroxam, manoxicam, maxidene, micar, murupe, musculox, noxflam, n-piroxicam meduman, n-piroxicam sintofarm, osteral, painrelipt, palpasin, pedifan, pemar, pesugen, pipo, pipon, piraldene, piram, piridene, piroalgin, pirobec, pirocam, pirocan, pirodene, pirofel, piroftal, pirom, piromed, pirorheum, pirosol, pirox, pirox-ct, piroxen, piroxicalm, piroxicam, piroxicam 0.5%, piroxicam abc, piroxicam abz, piroxicam acis, piroxicam actavis, piroxicam actor dt 20, piroxicam al, piroxicam alkaloid, piroxicam andromaco, piroxicam anglopharma, piroxicam antibiotice, piroxicam arena, piroxicam biogaran, piroxicam bussié, piroxicam cf, piroxicam cinfa, piroxicam colmed, piroxicam community pharma, piroxicam doc, piroxicam doc generici, piroxicam dupomar, piroxicam eg, piroxicam fabiol, piroxicam genfar, piroxicam germed, piroxicam glaxo, piroxicam gmp, piroxicam helcor, piroxicam hexal, piroxicam hwang's, piroxicam jelfa, piroxicam jg, piroxicam l.ch., piroxicam la santé, piroxicam laropharm, piroxicam long shine, piroxicam lph, piroxicam mintlab, piroxicam mk, piroxicam mylan, piroxicam newai chem, piroxicam pch, piroxicam pfizer, piroxicam ramos, piroxicam ratiopharm, piroxicam sandoz, piroxicam sandoz gmbh, piroxicam sanitas, piroxicam shou chan, piroxicam sopharma, piroxicam stada, piroxicam t.o., piroxicam taiyo, piroxicam teva, piroxicam vannier, piroxicam winthrop, piroxicam wise, piroxicam yimin, piroxicam ying yuan, piroxicam yung chi, piroxicam zydus, piroxicam-mepha, piroxicam-ratiopharm, piroxiden, piroxifar, piroxim, piroxim-d, piroxistad, piroxivar, piroxized, piroxsal, pitocam, piton, pixicam, pixtim, pms-piroxicam, polydene, poudercam, pricam, pro, proponol, proxalyoc, proxigel, proxyc, proxyc-ft, proxym, pyras, pyrocam, pyrocaps, pyrolox, raxicam, reliagic, remisil, reucam, reumador, reumagil, reumoxican, rexicam, rexil, rheugesic, riacen, rosiden, roxam, roxiden, roxidene, roxifen forte, roxycam, rumaxicam, rumolon, ruvamed, salvacam, sasulen, scandene, scanning, sefdene, semincon, shinpoong rosiden, shujen, solicam, solocalm, solocalm plus, solocalm-flex, sorocam, sotilen, suganril, suit, suswan tung, tecon, terry white chemists piroxicam, teva-piroxicam, tirovel, tonex, tonmex, toricam, trast, tropidene, turnstyle analgesia, unicam, vendocid, verand, vitaxicam, xicalom, xycam, zerospasm, zofora, sinartrol, sinartrol infiammazione e dolore, zelis, agipiro, brexecam, brexine, cicladol, cycladol, cyclodex, flamexin, flogene, nysa) |
| 1749 | 1 | Probiotic Mixture 2 {Vetafarm Probotic} | lactobacillus delbrueckii bulgaricus,bifidobacterium bifidum,enterococcus faecium |
| 368 | 1 | Saccharomyces cerevisiae var boulardii {S. boulardii} | brewer's yeast |
| 4509 | 1 | Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus {Bio-three} | A blend of Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus |
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