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Ankylosing spondylitis

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Common knowledge amoung some professionals (MD and ND):

  1. Antioxidants: Antioxidants such as vitamins C and E have been investigated for their potential to reduce oxidative stress, which is implicated in the progression of ALS. While research has not conclusively shown their effectiveness in slowing ALS progression, maintaining adequate levels of antioxidants through diet or supplements might be beneficial for overall health.

  2. Omega-3 Fatty Acids: Omega-3 fatty acids found in fish oil or certain plant sources possess anti-inflammatory properties. Some studies suggest that omega-3 supplementation might have a potential role in reducing inflammation and oxidative stress, which could be beneficial for individuals with ALS. However, evidence supporting their efficacy is limited.

  3. Vitamin D: Vitamin D deficiency has been associated with a higher risk of ALS. Some studies suggest that maintaining adequate vitamin D levels might have a neuroprotective effect and could potentially influence the risk or progression of ALS. However, more research is needed to establish a clear link.

  4. Probiotics: The gut microbiota's influence on overall health, including neurological conditions, has prompted research into the potential role of probiotics in ALS. While the exact mechanisms are not fully understood, maintaining a healthy gut microbiota through probiotics might have indirect effects on overall health. However, direct evidence linking probiotics to ALS prevention or treatment is lacking.


Bacteria/Taxa

The Studies below identify bacteria. Check if it has already been reviewed.

1 πŸ“š
A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin.
Arthritis research & therapy (Arthritis Res Ther ) Vol: 21 Issue: 1 Pages: 248 Pub: 2019 Nov 27 ePub: 2019 Nov 27 Authors Klingberg E,Magnusson MK,Strid H,Deminger A,StΓ₯hl A,Sundin J,SimrΓ©n M,Carlsten H,Γ–hman L,Forsblad-d`Elia H
2 πŸ“š
Altered Bacterial-Fungal Interkingdom Networks in the Guts of Ankylosing Spondylitis Patients.
mSystems (mSystems ) Vol: 4 Issue: 2 Pages: Pub: 2019 Mar-Apr ePub: 2019 Mar 26 Authors Li M,Dai B,Tang Y,Lei L,Li N,Liu C,Ge T,Zhang L,Xu Y,Hu Y,Li P,Zhang Y,Yuan J,Li X
3 πŸ“š
Ankylosing spondylitis is linked to Klebsiella--the evidence.
Clinical rheumatology (Clin Rheumatol ) Vol: 26 Issue: 6 Pages: 858-64 Pub: 2007 Jun ePub: 2006 Dec 21 Authors Rashid T,Ebringer A
4 πŸ“š
Antibodies against bacterial lipopolysaccharides in Japanese patients with ankylosing spondylitis.
British journal of rheumatology (Br J Rheumatol ) Vol: 36 Issue: 4 Pages: 491-3 Pub: 1997 Apr ePub: Authors Tani Y,Sato H,Tanaka N,Hukuda S
5 πŸ“š
Antibodies Directed against a Peptide Epitope of a Klebsiella pneumoniae-Derived Protein Are Present in Ankylosing Spondylitis.
PloS one (PLoS One ) Vol: 12 Issue: 1 Pages: e0171073 Pub: 2017 ePub: 2017 Jan 30 Authors Puccetti A,Dolcino M,Tinazzi E,Moretta F,D'Angelo S,Olivieri I,Lunardi C
6 πŸ“š
Antibodies to peptidoglycan in juvenile onset ankylosing spondylitis and pauciarticular onset juvenile arthritis associated with chronic iridocyclitis.
The Journal of rheumatology (J Rheumatol ) Vol: 13 Issue: 4 Pages: 760-2 Pub: 1986 Aug ePub: Authors Burgos-Vargas R,Howard A,Ansell BM
7 πŸ“š
Biochemical studies on a factor isolated from Klebsiella K43-BTS1 that cross-reacts with cells from HLA-B27 positive patients with ankylosing spondylitis.
Human immunology (Hum Immunol ) Vol: 17 Issue: 3 Pages: 224-38 Pub: 1986 Nov ePub: Authors Upfold LI,Sullivan JS,Geczy AF
8 πŸ“š
Brief Report: Intestinal Dysbiosis in Ankylosing Spondylitis.
Arthritis & rheumatology (Hoboken, N.J.) (Arthritis Rheumatol ) Vol: 67 Issue: 3 Pages: 686-691 Pub: 2015 Mar ePub: Authors Costello ME,Ciccia F,Willner D,Warrington N,Robinson PC,Gardiner B,Marshall M,Kenna TJ,Triolo G,Brown MA
9 πŸ“š
Causal relationship between gut microbiota and ankylosing spondylitis and potential mediating role of inflammatory cytokines: A mendelian randomization study.
PloS one (PLoS One ) Vol: 19 Issue: 7 Pages: e0306792 Pub: 2024 ePub: 2024 Jul 31 Authors Du X,Li H,Zhao H,Cui S,Sun X,Tan X
10 πŸ“š
Comparison of the faecal microflora of patients with ankylosing spondylitis and controls using molecular methods of analysis.
Rheumatology (Oxford, England) (Rheumatology (Oxford) ) Vol: 41 Issue: 12 Pages: 1395-401 Pub: 2002 Dec ePub: Authors Stebbings S,Munro K,Simon MA,Tannock G,Highton J,Harmsen H,Welling G,Seksik P,Dore J,Grame G,Tilsala-Timisjarvi A
11 πŸ“š
Discovery of fecal microbial signatures in patients with ankylosing spondylitis.
Archives of rheumatology (Arch Rheumatol ) Vol: 38 Issue: 2 Pages: 217-229 Pub: 2023 Jun ePub: 2022 Oct 21 Authors You Y,Zhang W,Cai M,Guo Q,Wang J,Cai Y,Lin J
12 πŸ“š
Fecal microbiota in patients with ankylosing spondylitis: Correlation with dietary factors and disease activity.
Clinica chimica acta; international journal of clinical chemistry (Clin Chim Acta ) Vol: 497 Issue: Pages: 189-196 Pub: 2019 Oct ePub: 2019 Aug 1 Authors Zhang L,Han R,Zhang X,Fang G,Chen J,Li J,Xu S,Qian L,Chen W,Pan F
13 πŸ“š
Gut Microbiota and Inflammatory Cytokine Changes in Patients with Ankylosing Spondylitis.
BioMed research international (Biomed Res Int ) Vol: 2022 Issue: Pages: 1005111 Pub: 2022 ePub: 2022 Aug 19 Authors Liu B,Ding Z,Xiong J,Heng X,Wang H,Chu W
14 πŸ“š
Gut microbiota and risk of ankylosing spondylitis.
Clinical rheumatology (Clin Rheumatol ) Vol: 43 Issue: 11 Pages: 3351-3360 Pub: 2024 Nov ePub: 2024 Sep 7 Authors Jiang X,Wang M,Liu B,Yang H,Ren J,Chen S,Ye D,Yang S,Mao Y
15 πŸ“š
Gut Microbiota is Altered in Patients with Alzheimer`s Disease.
Journal of Alzheimer`s disease : JAD (J Alzheimers Dis ) Vol: 63 Issue: 4 Pages: 1337-1346 Pub: 2018 ePub: Authors Zhuang ZQ,Shen LL,Li WW,Fu X,Zeng F,Gui L,LΓΌ Y,Cai M,Zhu C,Tan YL,Zheng P,Li HY,Zhu J,Zhou HD,Bu XL,Wang YJ
16 πŸ“š
Metagenome-wide association study of the alterations in the intestinal microbiome composition of ankylosing spondylitis patients and the effect of traditional and herbal treatment.
Journal of medical microbiology (J Med Microbiol ) Vol: Issue: Pages: Pub: 2019 Nov 28 ePub: 2019 Nov 28 Authors Huang R,Li F,Zhou Y,Zeng Z,He X,Fang L,Pan F,Chen Y,Lin J,Li J,Qiu D,Tian Y,Tan X,Song Y,Xu Y,Lai Y,Yi H,Gao Q,Fang X,Shi M,Zhou C,Huang J,He YT
17 πŸ“š
Proteomic analysis of serum-derived extracellular vesicles in ankylosing spondylitis patients.
International immunopharmacology (Int Immunopharmacol ) Vol: 87 Issue: Pages: 106773 Pub: 2020 Oct ePub: 2020 Jul 14 Authors Huang Y,Feng F,Huang Q,Zheng S,Huang Z,Deng W,Pan X,Li T
18 πŸ“š
Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis.
Genome biology (Genome Biol ) Vol: 18 Issue: 1 Pages: 142 Pub: 2017 Jul 27 ePub: 2017 Jul 27 Authors Wen C,Zheng Z,Shao T,Liu L,Xie Z,Le Chatelier E,He Z,Zhong W,Fan Y,Zhang L,Li H,Wu C,Hu C,Xu Q,Zhou J,Cai S,Wang D,Huang Y,Breban M,Qin N,Ehrlich SD
19 πŸ“š
Somatic serogroups, capsular types, and species of fecal Klebsiella in patients with ankylosing spondylitis.
Journal of clinical microbiology (J Clin Microbiol ) Vol: 37 Issue: 9 Pages: 2808-12 Pub: 1999 Sep ePub: Authors Toivanen P,Hansen DS,Mestre F,Lehtonen L,Vaahtovuo J,Vehma M,MΓΆttΓΆnen T,Saario R,Luukkainen R,NissilΓ€ M
20 πŸ“š
The Association of Fecal Microbiota in Ankylosing Spondylitis Cases with C-Reactive Protein and Erythrocyte Sedimentation Rate.
Mediators of inflammation (Mediators Inflamm ) Vol: 2020 Issue: Pages: 8884324 Pub: 2020 ePub: 2020 Nov 7 Authors Liu G,Hao Y,Yang Q,Deng S
21 πŸ“š
The link between ankylosing spondylitis, Crohn's disease, Klebsiella, and starch consumption.
Clinical & developmental immunology (Clin Dev Immunol ) Vol: 2013 Issue: Pages: 872632 Pub: 2013 ePub: 2013 May 27 Authors Rashid T,Wilson C,Ebringer A
22 πŸ“š
Variations in gut microbial profiles in ankylosing spondylitis: disease phenotype-related dysbiosis.
Annals of translational medicine (Ann Transl Med ) Vol: 7 Issue: 20 Pages: 571 Pub: 2019 Oct ePub: Authors Chen Z,Qi J,Wei Q,Zheng X,Wu X,Li X,Liao Z,Lin Z,Gu J

Treatment Substances

The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.

23 πŸ“š
Inhibition of Klebsiella pneumoniae growth by selected Australian plants: natural approaches for the prevention and management of ankylosing spondylitis.
Inflammopharmacology (Inflammopharmacology ) Vol: 25 Issue: 2 Pages: 223-235 Pub: 2017 Apr ePub: 2017 Feb 27 Authors Winnett V,Sirdaarta J,White A,Clarke FM,Cock IE
24 πŸ“š
Treatment of ankylosing spondylitis with moxifloxacin.
Southern medical journal (South Med J ) Vol: 100 Issue: 4 Pages: 366-70 Pub: 2007 Apr ePub: Authors Ogrendik M

Quick Reference

The following items have been cited in the above studies

IDStudiesNameAKA
504 1   moxifloxacin (antibiotic) (actimoxiflox, advancrib, akamoxx, apdrops, apdrops dx, atafloks, avalox, avelox, avemox, biofloxacin, cinagen, delmoxa, dominal, eye-quin, flomox, flovacil, floxamic, floxitrat, floxsafe, fluroquinomox 0.5%, fortymox 0.5%, getmoxy, idelox, imix, mahaflox, megaxin, mevafast, mofelox, mofinacin, moflox, mofloxin lafrancol, mograflox 0.5%, moksacin, moksefen, moksifloksacin alvogen, moksifloksacin pharmas, moloxin, monafox, morris, mosi, mosi-d, moxacin, moxai, moxavidex, moxday, moxi, moxibact, moxicip, moxicum, moxieye, moxifloksacin lek, moxiflox, moxifloxacin actavis, moxifloxacin aurobindo, moxifloxacin kabi, moxifloxacin ratiopharm, moxifloxacin sabaa, moxifloxacina aurobindo, moxifloxacina la santé, moxifloxacine teva, moxifloxacin-mepha, moxifloxacino ratiopharm, moxifloxacino tevagen, moxifloxacin-ratiopharm, moxifor, moxigram, moxiquin, moxital, moxitec, moxitrix, moxivin, moxof, moxoft, oftamox, oftamox d, omnimox, pitoxil, pitoxil-sanovel, plivamox, quinomax, raspelocin, rowamoxiflox, staxom, unomox, vigadexa, vigamox, vigamox 0.5%, xiflodrop, actira, avebact, avelon, cenomar, cimocinox, drl moxifloxacin, eyemox, flamix, floromox, iventi, izilox, kanavig, lamoflox, lifodrox, litares, maxiflox, mikrobiel, mofil, moflag, moflag d, moflaxa, moflodal, moxaval, moxeza, moxflodel, moxibay, moxicino, moxiflo, moxifloxacin - 1 a pharma, moxifloxacin 1a pharma, moxifloxacin abz, moxifloxacin al, moxifloxacin apotex, moxifloxacin fresenius kabi, moxifloxacin heumann, moxifloxacin hexal, moxifloxacin krka, moxifloxacin noridem, moxifloxacin rivopharm, moxifloxacin sandoz, moxifloxacin spirig hc, moxifloxacin stada, moxifloxacin tad, moxifloxacin teva, moxifloxacina mk, moxifloxacin-actavis, moxifloxacine double-e pharma, moxifloxacine eg, moxifloxacine fresenius kabi, moxifloxacine krka, moxifloxacine mylan, moxifloxacine pch, moxifloxacine sandoz, moxifloxacino actavis, moxifloxacino apotex, moxifloxacino aurobindo, moxifloxacino cinfa, moxifloxacino kern pharma, moxifloxacino krka, moxifloxacino mylan, moxifloxacino qualigen, moxifloxacino sandoz, moxifloxacino stada, moxifloxacino zentiva, moxiforce, moxikacin, moxis, moxista, moxi-tech, moxivig, moxivig 0.5%, moxquin, numoxx, octegra, optimox, praxinstad, quinomed dx, rucela, vegamox 0.5%)
4438 1   Piper nigrum {black pepper} Common pepper,Peppercorn,Kali Mirch,Kali Miri,Kurumulaku

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