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Sleep Apnea

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Common knowledge amoung some professionals (MD and ND):

  1. Melatonin: Melatonin is a hormone that regulates the sleep-wake cycle. Some individuals with sleep disturbances might explore melatonin supplementation to improve sleep quality or address sleep-related issues. However, its role in managing sleep apnea symptoms specifically is not well-established.

  2. Magnesium: Magnesium is involved in various physiological processes, including muscle relaxation and sleep regulation. Some individuals might explore magnesium supplementation to promote relaxation and potentially improve sleep quality. However, evidence specifically targeting sleep apnea is limited.

  3. Vitamin D: Adequate levels of vitamin D are important for overall health, including potential effects on sleep regulation. Some research suggests a potential link between low vitamin D levels and sleep disturbances. However, evidence supporting its effectiveness for sleep apnea is not well-established.

  4. Probiotics: While not directly related to sleep apnea, some research suggests that probiotics might have a role in influencing overall health, including potential effects on sleep quality and inflammation. However, specific effects on sleep apnea require further investigation.


Bacteria/Taxa

The Studies below identify bacteria. Check if it has already been reviewed.

1 πŸ“š
[Preliminary analysis of intestinal microflora in patients with different severity of OSAHS].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases (Zhonghua Jie He He Hu Xi Za Zhi ) Vol: 44 Issue: 6 Pages: 543-549 Pub: 2021 Jun 12 ePub: Authors Wang LJ,Yang C,Dou ZJ,Wang PP,Hu ZX,Wang B
2 πŸ“š
Assessing the causal association between sleep apnea and the human gut microbiome composition: A two-sample Mendelian randomization study.
SAGE open medicine (SAGE Open Med ) Vol: 12 Issue: Pages: 20503121241248044 Pub: 2024 ePub: 2024 May 6 Authors Yu M,Chen X,Huang X,Gao X
3 πŸ“š
Associations of OSAHS complicated by cerebral infarction with intestinal flora, inflammatory factors, homocysteine and adiponectin expression.
European review for medical and pharmacological sciences (Eur Rev Med Pharmacol Sci ) Vol: 24 Issue: 24 Pages: 12993-12999 Pub: 2020 Dec ePub: Authors Zhang WT,Niu JY,He C
4 πŸ“š
Causal relationship between Gut Microbiota and Obstructive sleep apnea.
Archives of gerontology and geriatrics (Arch Gerontol Geriatr ) Vol: 113 Issue: Pages: 105052 Pub: 2023 May 1 ePub: 2023 May 1 Authors Wei Y,Huang L,Liu C,Qi M
5 πŸ“š
Causality Investigation between Gut Microbiota, Derived Metabolites, and Obstructive Sleep Apnea: A Bidirectional Mendelian Randomization Study.
Nutrients (Nutrients ) Vol: 15 Issue: 21 Pages: Pub: 2023 Oct 26 ePub: 2023 Oct 26 Authors Yan W,Jiang M,Hu W,Zhan X,Liu Y,Zhou J,Ji J,Wang S,Tai J
6 πŸ“š
Evaluation of obstructive sleep apnea in non-cystic fibrosis bronchiectasis: A cross-sectional study.
PloS one (PLoS One ) Vol: 12 Issue: 10 Pages: e0185413 Pub: 2017 ePub: 2017 Oct 3 Authors Faria JΓΊnior NS,Urbano JJ,Santos IR,Silva AS,Perez EA,Souza Γ‚H,Nascimento OA,Jardim JR,Insalaco G,Oliveira LVF,Stirbulov R
7 πŸ“š
Gut microbiota and metabolic profiles in chronic intermittent hypoxia-induced rats: disease-associated dysbiosis and metabolic disturbances.
Frontiers in endocrinology (Front Endocrinol (Lausanne) ) Vol: 14 Issue: Pages: 1224396 Pub: 2023 ePub: 2024 Jan 12 Authors Li C,Shi S
8 πŸ“š
Is the Gut Microbiome Implicated in the Excess Risk of Hypertension Associated with Obstructive Sleep Apnea? A Contemporary Review.
Antioxidants (Basel, Switzerland) (Antioxidants (Basel) ) Vol: 12 Issue: 4 Pages: Pub: 2023 Apr 3 ePub: 2023 Apr 3 Authors Munir SS,Sert Kuniyoshi FH,Singh P,Covassin N
9 πŸ“š
Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.
Frontiers in microbiology (Front Microbiol ) Vol: 16 Issue: Pages: 1572637 Pub: 2025 ePub: 2025 May 15 Authors Guo Y,Sun S,Wang Y,Chen S,Kou Z,Yuan P,Han W,Yu X

Treatment Substances

The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.

10 πŸ“š
Gut microbiota mediate vascular dysfunction in a murine model of sleep apnea: effect of probiotics.
The European respiratory journal (Eur Respir J ) Vol: Issue: Pages: Pub: 2022 Aug 25 ePub: 2022 Aug 25 Authors Badran M,Khalyfa A,Ericsson A,Puech C,McAdams Z,Bender SB,Gozal D
11 πŸ“š
Lactobacillus rhamnosus GG strain mitigated the development of obstructive sleep apnea-induced hypertension in a high salt diet via regulating TMAO level and CD4+ T cell induced-type I inflammation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (Biomed Pharmacother ) Vol: 112 Issue: Pages: 108580 Pub: 2019 Apr ePub: 2019 Feb 18 Authors Liu J,Li T,Wu H,Shi H,Bai J,Zhao W,Jiang D,Jiang X

Quick Reference

The following items have been cited in the above studies

IDStudiesNameAKA
247 1   lactobacillus rhamnosus gg l rhamnosus gg (probiotics)
426 1   Vsl#3 {Visibiome} Warning: Formula changed. VSL#3 DS,VSL#3 900,Visibiome

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