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Eosinophilic Esophagitis

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Common knowledge amoung some professionals (MD and ND):

  1. Probiotics: Probiotics might help modulate gut flora and potentially influence immune responses, which could be relevant in allergic conditions like EoE. Some research suggests that certain probiotics might have a role in managing EoE, but the specific strains, dosages, and effectiveness are still under investigation.

  2. Omega-3 Fatty Acids: Omega-3 supplements containing EPA and DHA have anti-inflammatory properties. While their exact impact on EoE is not well-documented, they may have some potential to reduce inflammation, which could theoretically help manage symptoms.

  3. Vitamin D: Adequate vitamin D levels are important for immune function and overall health. Some studies suggest a potential link between vitamin D deficiency and increased risk or severity of allergic conditions. However, specific evidence supporting vitamin D supplementation for EoE is limited.

  4. Quercetin: Quercetin, a flavonoid found in some fruits and vegetables, has anti-inflammatory properties. It might have a theoretical role in managing allergic conditions like EoE, but its specific impact on EoE requires further investigation.

  5. Digestive Enzymes: In some cases, digestive enzyme supplements might be used to help break down food proteins and alleviate symptoms associated with EoE. However, their use should be guided by healthcare professionals.


Bacteria/Taxa

The Studies below identify bacteria. Check if it has already been reviewed.

1 πŸ“š
A decreased abundance of clostridia characterizes the gut microbiota in eosinophilic esophagitis.
Physiological reports (Physiol Rep ) Vol: 7 Issue: 20 Pages: e14261 Pub: 2019 Oct ePub: Authors Kashyap PC,Johnson S,Geno DM,Lekatz HR,Lavey C,Alexander JA,Chen J,Katzka DA
2 πŸ“š
Causality of Helicobacter pylori infection on eosinophilic esophagitis and potential pathogenesis: a Mendelian randomization study.
Frontiers in immunology (Front Immunol ) Vol: 15 Issue: Pages: 1365604 Pub: 2024 ePub: 2024 May 8 Authors Zhu Z,Yang Y,Han X,Peng L,Zhu H
3 πŸ“š
Eosinophilic esophagitis and esophageal microbiota.
Frontiers in cellular and infection microbiology (Front Cell Infect Microbiol ) Vol: 13 Issue: Pages: 1206343 Pub: 2023 ePub: 2023 Aug 3 Authors Zhang X,Zhang N,Wang Z
4 πŸ“š
Esophageal microbiome in active eosinophilic esophagitis and changes induced by different therapies.
Scientific reports (Sci Rep ) Vol: 11 Issue: 1 Pages: 7113 Pub: 2021 Mar 29 ePub: 2021 Mar 29 Authors Laserna-Mendieta EJ,FitzGerald JA,Arias-Gonzalez L,Ollala JM,Bernardo D,Claesson MJ,Lucendo AJ
5 πŸ“š
Esophageal microbiome in eosinophilic esophagitis.
PloS one (PLoS One ) Vol: 10 Issue: 5 Pages: e0128346 Pub: 2015 ePub: 2015 May 28 Authors Harris JK,Fang R,Wagner BD,Choe HN,Kelly CJ,Schroeder S,Moore W,Stevens MJ,Yeckes A,Amsden K,Kagalwalla AF,Zalewski A,Hirano I,Gonsalves N,Henry LN,Masterson JC,Robertson CE,Leung DY,Pace NR,Ackerman SJ,Furuta GT,Fillon SA
6 πŸ“š
Inflammation-associated microbiota in pediatric eosinophilic esophagitis.
Microbiome (Microbiome ) Vol: 3 Issue: Pages: 23 Pub: 2015 ePub: 2015 Jun 1 Authors Benitez AJ,Hoffmann C,Muir AB,Dods KK,Spergel JM,Bushman FD,Wang ML
7 πŸ“š
Low Prevalence of Extraesophageal Gastrointestinal Pathology in Patients with Eosinophilic Esophagitis.
Digestive diseases and sciences (Dig Dis Sci ) Vol: 67 Issue: 7 Pages: 3080-3088 Pub: 2022 Jul ePub: 2021 Jun 30 Authors Hiramoto B,Zalewski A,Gregory D,Yang GY,Ho N,Gonsalves N,Hirano I
8 πŸ“š
The Relationship Between Bacterial Flora in Saliva and Esophageal Mucus and Endoscopic Severity in Patients with Eosinophilic Esophagitis.
International journal of molecular sciences (Int J Mol Sci ) Vol: 26 Issue: 7 Pages: Pub: 2025 Mar 26 ePub: 2025 Mar 26 Authors Sasahira M,Matsumoto H,Go TT,Yo S,Monden S,Ninomiya T,Oosawa M,Handa O,Umegaki E,Inoue R,Shiotani A

Treatment Substances

The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.

Quick Reference

The following items have been cited in the above studies

IDStudiesNameAKA

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