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Common knowledge amoung some professionals (MD and ND):
Alpha-Lipoic Acid: Alpha-lipoic acid, an antioxidant, is sometimes used for individuals with diabetic neuropathy. It may have neuroprotective effects and could potentially help reduce symptoms like pain or tingling. However, evidence regarding its effectiveness is mixed, and it may not work for everyone.
Vitamin B Complex: Certain B vitamins, particularly B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin), are essential for nerve health and function. Some individuals with neuropathy, especially those with deficiencies, might benefit from B vitamin supplementation. However, excessive doses should be avoided as they might have adverse effects.
Omega-3 Fatty Acids: Omega-3 fatty acids found in fish oil or certain plant-based sources may have anti-inflammatory properties that could potentially provide general health support. Some studies suggest they might help reduce inflammation and nerve damage, but their specific role in neuropathy requires further research.
Vitamin D: Adequate levels of vitamin D are important for overall health. Some research suggests a potential association between low vitamin D levels and neuropathy. However, its direct impact on neuropathy is not fully understood.
Probiotics: While not directly related to neuropathy, maintaining a healthy gut microbiome might indirectly support overall health. Some studies suggest that probiotics might have a role in modulating inflammation and immune function, which could potentially impact certain neuropathic conditions.
The Studies below identify bacteria. Check if it has already been reviewed.
| 1 | 📚 |
Alterations in the gut microbiota and metabolite profiles in the context of neuropathic pain.
Molecular brain (Mol Brain ) Vol: 14 Issue: 1 Pages: 50 Pub: 2021 Mar 9 ePub: 2021 Mar 9 Authors Chen P,Wang C,Ren YN,Ye ZJ,Jiang C,Wu ZB |
| 2 | 📚 |
Changes of intestinal microbiome and its relationship with painful diabetic neuropathy in rats.
BMC microbiology (BMC Microbiol ) Vol: 25 Issue: 1 Pages: 281 Pub: 2025 May 8 ePub: 2025 May 8 Authors Jia S,Mi H,Su Y,Liu Y,Ming Z,Lin J |
| 3 | 📚 |
Chlamydia in anterior ischemic optic neuropathy.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde (Ophthalmologica ) Vol: 216 Issue: 3 Pages: 215-20 Pub: 2002 May-Jun ePub: Authors Vécsei PV,Kircher K,Reitner A,Khanakha G,Stanek G |
| 4 | 📚 |
Distinctive Microbial Signatures and Gut-Brain Crosstalk in Pediatric Patients with Coeliac Disease and Type 1 Diabetes Mellitus.
International journal of molecular sciences (Int J Mol Sci ) Vol: 22 Issue: 4 Pages: Pub: 2021 Feb 3 ePub: 2021 Feb 3 Authors Singh P,Rawat A,Al-Jarrah B,Saraswathi S,Gad H,Elawad M,Hussain K,Hendaus MA,Al-Masri W,A Malik R,Al Khodor S,Akobeng AK |
| 5 | 📚 |
Gut dysbiosis in patients with chronic pain: a systematic review and meta-analysis.
Frontiers in immunology (Front Immunol ) Vol: 15 Issue: Pages: 1342833 Pub: 2024 ePub: 2024 Jan 30 Authors Goudman L,Demuyser T,Pilitsis JG,Billot M,Roulaud M,Rigoard P,Moens M |
| 6 | 📚 |
Integrated 16S rRNA Gene Sequencing and Metabolomics Analysis to Investigate the Important Role of Osthole on Gut Microbiota and Serum Metabolites in Neuropathic Pain Mice.
Frontiers in physiology (Front Physiol ) Vol: 13 Issue: Pages: 813626 Pub: 2022 ePub: 2022 Feb 7 Authors Li R,Wang F,Dang S,Yao M,Zhang W,Wang J |
| 7 | 📚 |
Optic nerve involvement in Lyme disease.
Current opinion in ophthalmology (Curr Opin Ophthalmol ) Vol: 23 Issue: 6 Pages: 485-90 Pub: 2012 Nov ePub: Authors Träisk F,Lindquist L |
The Studies below identify substances that has been tried with positive changes (for at least some symptoms in the study). Check if it has already been reviewed.
| 8 | 📚 |
Acute and subchronic in-vivo effects of Ferula hermonis L. and Sambucus nigra L. and their potential active isolates in a diabetic mouse model of neuropathic pain.
BMC complementary and alternative medicine (BMC Complement Altern Med ) Vol: 15 Issue: Pages: 257 Pub: 2015 Jul 30 ePub: 2015 Jul 30 Authors Raafat K,El-Lakany A |
| 9 | 📚 |
Antidepressant effect of carvedilol on streptozotocin-induced diabetic peripheral neuropathy mice by altering gut microbiota.
Biochemical and biophysical research communications (Biochem Biophys Res Commun ) Vol: 730 Issue: Pages: 150374 Pub: 2024 Oct 20 ePub: 2024 Jul 9 Authors Wu W,Zeng C,Wu C,Wu T,Pang J,Zhou P,Cao Y |
| 10 | 📚 |
Fucoidan reduces NET accumulation and alleviates chemotherapy-induced peripheral neuropathy via the gut-blood-DRG axis.
Journal of neuroinflammation (J Neuroinflammation ) Vol: 22 Issue: 1 Pages: 100 Pub: 2025 Apr 4 ePub: 2025 Apr 4 Authors Jia R,Wan L,Jin L,Tian Q,Chen Y,Zhu X,Zhang M,Zhang Y,Zong L,Wu X,Miao C,Cai Y,Ma J,Hu L,Liu WT |
| 11 | 📚 |
Ginger alleviates mechanical hypersensitivity and anxio-depressive behavior in rats with diabetic neuropathy through beneficial actions on gut microbiome composition, mitochondria, and neuroimmune cells of colon and spinal cord.
Nutrition research (New York, N.Y.) (Nutr Res ) Vol: 124 Issue: Pages: 73-84 Pub: 2024 Apr ePub: 2024 Feb 1 Authors Shen CL,Wang R,Santos JM,Elmassry MM,Stephens E,Kim N,Neugebauer V |
The following items have been cited in the above studies
| ID | Studies | Name | AKA |
|---|---|---|---|
| 816 | 1 | carvedilol,(prescription) | (acarden, anisto, antibloc, apo-carve, apo-carvedilol, arlec, artist, aspen carvedilol, atenote, atram, avedol, avernol, betacar, betacard, betaplex, bicol, bidecar, blocar, bloquedil, blorec, cadil, cadiron, calbicor, caraten, caravel, carbatil, carbloxal, cardibru carvedilol-brupharm, cardilo, cardilol, cardilol cs, cardiol, cardionorm, cardiostad, cardipres, cardirat, cardoz, carelol, carlatrend, carloc, carlol v, carsantin, carvecare, carved, carvedexxon, carvedi-denk, carvedigamma, carvedil, carvedil d, carvedil garmisch, carvedilen, carvedilol, carvedilol - 1 a pharma, carvedilol 1a pharma, carvedilol abz, carvedilol actavis, carvedilol al, carvedilol alapis, carvedilol almus, carvedilol alter, carvedilol alternova, carvedilol alvogen, carvedilol amel, carvedilol apotex, carvedilol aristo, carvedilol atid, carvedilol aurobindo, carvedilol azevedos, carvedilol bexalabs, carvédilol biogaran, carvedilol biopharm, carvedilol cf, carvedilol cherubino, carvedilol ciclum, carvedilol cinfa, carvedilol cipla, carvedilol combix, carvedilol coronat, carvedilol dura, carvedilol edigen, carvedilol eg, carvédilol eg, carvedilol eql pharma, carvedilol farmabion, carvedilol farmoz, carvedilol genericon, carvedilol generis, carvedilol genfar, carvedilol germed, carvedilol gp, carvedilol grindeks, carvedilol helcor, carvedilol helvepharm, carvedilol hexal, carvedilol jaba, carvedilol kern pharma, carvedilol korhispana, carvedilol krka, carvedilol la santé, carvedilol labesfal, carvedilol lph, carvedilol metropolis, carvedilol mintlab, carvedilol mylan, carvédilol mylan, carvedilol normon, carvedilol northia, carvedilol opko, carvedilol orion, carvedilol orion pharma, carvedilol p d, carvedilol pcd, carvedilol pch, carvedilol pfizer, carvedilol pharmacia, carvedilol pharmagenus, carvedilol ratiopharm, carvedilol richet, carvedilol sandoz, carvedilol sanis health, carvedilol sanitas, carvedilol sawai, carvedilol shasun, carvedilol spirig hc, carvedilol stada, carvedilol tanabe, carvedilol tatsumi, carvedilol tecnigen, carvedilol teva, carvédilol teva, carvedilol tillomed, carvedilol towa, carvedilol unicorn, carvedilol vim, carvedilol winthrop, carvedilol zentiva, carvédilol zentiva, carvedilol-ct, carvedilolhexal, carvedilol-mepha, carvedilolo actavis, carvedilolo almus, carvedilolo alter, carvedilolo angenerico, carvedilolo arrow, carvedilolo awp, carvedilolo doc, carvedilolo dr reddy's, carvedilolo eg, carvedilolo fg, carvedilolo germed, carvedilolo hexal, carvedilolo mylan, carvedilolo pensa, carvedilolo pfizer, carvedilolo ranbaxy, carvedilolo ratiopharm, carvedilolo sandoz, carvedilolo sigma tau, carvedilolo zentiva, carvedilol-ratiopharm, carvedilol-teva, carvedilolum 123ratio, carveditas, carveheal, carvejohn, carvelix, carvelol, carvena, carvenal, carvepen, carve-q, carveratio, carvesan, carvestad, carvetrend, carvex, carvexal, carvicor, carvid, carvida, carvidex, carvidil, carvidol, carvil, carvilex, carviloc, carvio, carvipress, carvista, carvitol, carvo, carvol, caslot, cavelon, cepiron, cevas, chemmart carvedilol, cilokare, cliarvas, cloraten, co dilatrol, co-dilatrend, colver, conalend, conpres, corafen, coreg, coreg cr, coritensil, coronis, coropres, cortop, corubin, coryol, coryol sandoz, coventrol, curcix, dicartel, dicarz, dilapress, dilasig, dilatren, dilatrend, dilatrend d, dilatrend sr, dilatrol, dilbloc, dilgard, dimetil, dimitone, diola, divelol, dualten, duobloc, durol, durol-cr, entarsol, eucardic, exepress, filten, filten d, filten lp, genrx carvedilol, gladycor, gliocarvedil, gn-carvedilol, hipoten, hypoten, ictus, intrack, isobloc, isobloc d, jin luo, kailuo, kang da xin, karvedil, karvedilol, karvedilol labormed, karvedilol replekfarm, karvex, karvil, karvileks, ke wei de, kollosteril, kredex, lodipres, longcardio, luode, milenol, miocarvil, nexocardil, normotride, off-ten, omeria, oricar, pluscor, pms-carvedilol, querto, ran-carvedilol, ratio-carvedilol, revodil, rodipal, rovedilol, rudoxil, rui xin le, sandoz carvedilol, shuheng, symtrend, syntrend, talliton, tenvedil, terry white chemists carvedilol, tocarlol, trakor, tuo er, ucardol, v bloc, vasicard, vasolexin, vasotrol, v-bloc, vediblok, vedicor, vedilep, vedilol, veraten, vicardol, vivacor, xicard, zhuo yi, veraten ud) |
| 3154 | 1 | fucoidan {Brown Algae Extract} | Commercially extracted from Fucus vesiculosus (wracks), Cladosiphon okamuranus, Laminaria japonica (kombu, sugar kelp), and Undaria pinnatifida (wakame). |
| 2863 | 1 | Sambucus nigra L. ssp. canadensis {Elderberry} | Sweet elder,Wild elder,Flor sauco,Tree of music,Danewort,Walewort,New Mexican elderberry,Velvet-leaf elder,Hairy blue elderberry,Dwarf elder,Common elder |
| 163 | 1 | Zingiber officinale Roscoe {ginger} | Jiang,Adrak |
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