Modelled supplements for Alzheimer's disease

Conventional Beliefs

1. Omega-3 Fatty Acids: Omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) found in fish oil or certain plant sources, are important for brain health. Some studies suggest that omega-3 supplementation might support cognitive function and potentially reduce the risk of cognitive decline. However, results from studies have been mixed, and more research is needed.

2. Vitamin E: Vitamin E, particularly the form alpha-tocopherol, is an antioxidant that has been investigated for its potential to slow the progression of Alzheimer's disease. Some studies have suggested that vitamin E supplementation might have modest benefits in slowing functional decline in individuals with moderate Alzheimer's disease.

3. Vitamin B12 and Folate: Deficiencies in vitamin B12 and folate have been linked to cognitive impairment and may contribute to worsening symptoms in Alzheimer's disease. Ensuring adequate intake of these vitamins through diet or supplementation might be important for overall brain health.

4. Curcumin: Curcumin, a compound found in turmeric, has antioxidant and anti-inflammatory properties. Some research suggests that curcumin may have potential in reducing amyloid plaques (abnormal protein deposits) in the brain, which are characteristic of Alzheimer's disease. However, evidence supporting its efficacy is limited.

5. Probiotics: The relationship between gut health and brain health, known as the gut-brain axis, has prompted some research into the potential role of probiotics in neurological conditions. While the exact mechanisms are not fully understood, maintaining a healthy gut microbiota through probiotics might have indirect effects on overall health, including brain health. However, direct evidence linking probiotics to the prevention or treatment of Alzheimer's disease is lacking.

For an explanation of how this is generated, see this post

All suggestions from this page should be reviewed by your medical professionals. These are based on modelling and not clinical studies.

Based on family and lower taxonomy ranks (genus,species,strains) reported in studies, the list is here