Lawsonia intracellularis Details: NCBI 29546, gram-negative or unknown [species]

| "Candidatus intracellularis" Murray and Stackebrandt 1995| "Ileal symbiont intracellularis" Gebhart et al. 1993| Candidatus intracellularis| Ileal symbiont intracellularis| Lawsonia intracellularis| Lawsonia intracellularis McOrist et al. 1995| NCTC 12656| strain 1482/89

1. Proliferative Enteropathy:

   • Lawsonia intracellularis causes proliferative enteropathy, a disease characterized by the thickening of the intestines due to the proliferation of infected cells. This can lead to diarrhea, weight loss, and reduced growth rates in affected animals.

2. Swine Proliferative Enteropathy (SPE):

   • In swine, Lawsonia intracellularis is a significant concern, especially in intensive pig farming. Piglets and growing pigs are particularly susceptible to the infection, which can result in economic losses for the swine industry.

3. Equine Proliferative Enteropathy (EPE):

   • Lawsonia intracellularis can also cause proliferative enteropathy in horses. However, clinical signs in horses may vary, and the disease's impact on equine health can be less severe than in swine.

4. Zoonotic Potential:

   • Lawsonia intracellularis is generally not considered zoonotic, meaning it does not commonly infect humans. Human infections are rare, and when they occur, they are typically associated with occupational exposure to infected animals.

5. Prevention and Control:

   • Disease prevention and control in animals often involve good management practices, biosecurity measures, and, in some cases, vaccination strategies. Control of Lawsonia intracellularis in swine, for example, may include the use of antibiotics or vaccination.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Lawsonia intracellularis

• Lab Low and High are calculated using the formula that most labs use: Mean - 1.95 Standard Deviation to Mean + 1.95 Standard Deviation

These are values that are computed from lab specific samples and are in percentage

Lab	Frequency	Average	Median	Minimum	Maximum	Std.Dev.	Skew	25 - 75 Percentile	5 - 95 Percentile	Lab Ranges	Box-Plot-Whiskers	Harmonic Mean	Geometric Mean	Obs.
BiomeSight	0.0084	0.0018	0.002	0.001	0.004	0.0007	-0.8256	0.001 - 0.002	0.001 - 0.003	0.0004 - 0.0032	-0.0005 - 0.0035	0.0016	0.0017	31
Thorne	0.3492	0.0002	0.0002	0.0001	0.0012	0.0002	0.5738	0.0001 - 0.0003	0.0001 - 0.0007	-0.0002 - 0.0006	-0.0002 - 0.0006	0.0002	0.0002	66
Thryve	0.4718	0.0175	0.0054	0.0001	4.4852	0.1859	0.1961	0.0027 - 0.0106	0.0012 - 0.0308	-0.3449 - 0.38	-0.0092 - 0.0225	0.0031	0.0057	585

External Reference Ranges for Lawsonia intracellularis

Lawsonia intracellularis (NCBI 29546) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	2.1405869119917043E-05	0.0008273515850305557	0	0

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