Giardia ardeae Details: NCBI 5743, gram-negative or unknown [species]

1. Gastrointestinal Symptoms: Giardiasis typically causes symptoms such as:

   • Diarrhea: Often watery or greasy, sometimes alternating with constipation.
   • Abdominal pain and cramps: Ranging from mild discomfort to severe pain.
   • Bloating and flatulence: Excessive gas production and abdominal bloating may occur.
   • Nausea and vomiting: Some individuals may experience nausea and vomiting, especially in acute infections.

2. Dehydration and Malnutrition: Persistent diarrhea and vomiting in giardiasis can lead to dehydration and malnutrition, particularly in young children, older adults, and immunocompromised individuals.

3. Chronic or Recurrent Infections: In some cases, Giardia intestinalis infections may become chronic or recurrent, leading to long-term gastrointestinal symptoms and poor quality of life. Chronic giardiasis is more common in individuals with weakened immune systems or underlying health conditions.

4. Malabsorption and Weight Loss: Giardia parasites can interfere with the absorption of nutrients in the small intestine, leading to malabsorption of fats, carbohydrates, and proteins. Chronic giardiasis may result in weight loss and nutritional deficiencies.

5. Complications: While giardiasis is usually self-limiting and resolves without complications, severe or untreated cases may lead to complications such as:

   • Reactive arthritis: Inflammation of the joints, which can occur as a rare complication of giardiasis.
   • Guillain-Barré syndrome: An autoimmune disorder that affects the peripheral nervous system, although the association with Giardia infections is rare.

6. Impact on Quality of Life: Giardiasis can significantly impact an individual's quality of life due to the persistent gastrointestinal symptoms, discomfort, and disruption of daily activities.

7. Transmission: Giardia intestinalis parasites are typically transmitted through the ingestion of contaminated food or water, often from sources contaminated with fecal matter containing Giardia cysts. Outbreaks of giardiasis have been associated with contaminated drinking water sources, recreational water facilities, and foodborne transmission.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

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