Mycobacteriales: NCBI 85007, [order]

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| Corynebacteriales| Corynebacteriales Goodfellow and Jones 2015 emend. Nouioui et al. 2018| Corynebacterineae| Corynebacterineae Stackebrandt et al. 1997 emend. Zhi et al. 2009| Mycobacteria

1. Normal Microbiota: Some members of the order Corynebacteriales are part of the normal microbiota in humans and animals. For example, Corynebacterium species are commonly found on the skin and mucous membranes. They contribute to the microbial community that inhabits various body surfaces.

2. Opportunistic Pathogens: While many Corynebacteriales bacteria are harmless commensals, some can act as opportunistic pathogens. Corynebacterium species, including Corynebacterium diphtheriae, can cause infections under certain conditions. C. diphtheriae is the bacterium responsible for diphtheria, a potentially serious respiratory disease.

3. Diphtheria: Diphtheria is a bacterial infection caused by Corynebacterium diphtheriae. The disease primarily affects the respiratory tract, leading to symptoms such as sore throat, fever, and the formation of a characteristic pseudomembrane in the throat. Diphtheria can be severe and life-threatening if not treated promptly.

4. Toxin Production: Corynebacterium diphtheriae produces a potent exotoxin known as diphtheria toxin. The toxin is a major virulence factor and can lead to the characteristic symptoms of diphtheria. Immunization with the diphtheria vaccine is a key preventive measure against this disease.

5. Cutaneous Infections: Some Corynebacterium species, such as Corynebacterium minutissimum, can be associated with cutaneous infections. These infections may manifest as erythrasma, a superficial skin condition.

6. Skin Microbiota: Other Corynebacteriales bacteria are part of the normal skin microbiota and play a role in maintaining skin health. They contribute to the defense against pathogenic microorganisms and influence skin immune responses.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Mycobacteriales impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.337690144777298	0.5901869535446167	Actinomycetales	Parent Taxa
0.26446640491485596	0.5241237878799438	Lactobacillales	Parent Taxa
0.26428210735321045	-0.5239414572715759	Bacteroidales	Parent Taxa
0.2507384717464447	0.506405234336853	Micrococcales	Parent Taxa

Other bacteria of the same rank impacting Mycobacteriales

R2	Slope	Tax Name	Parent Chart
0.33450666069984436	0.5820717811584473	Actinomycetales	Parent Taxa
0.28142744302749634	-0.5274096131324768	Bacteroidales	Parent Taxa
0.2521093487739563	0.49850231409072876	Lactobacillales	Parent Taxa