Antioxidants: Antioxidants such as vitamins C and E have been investigated for their potential to reduce oxidative stress, which is implicated in the progression of ALS. While research has not conclusively shown their effectiveness in slowing ALS progression, maintaining adequate levels of antioxidants through diet or supplements might be beneficial for overall health.

Omega-3 Fatty Acids: Omega-3 fatty acids found in fish oil or certain plant sources possess anti-inflammatory properties. Some studies suggest that omega-3 supplementation might have a potential role in reducing inflammation and oxidative stress, which could be beneficial for individuals with ALS. However, evidence supporting their efficacy is limited.

Vitamin D: Vitamin D deficiency has been associated with a higher risk of ALS. Some studies suggest that maintaining adequate vitamin D levels might have a neuroprotective effect and could potentially influence the risk or progression of ALS. However, more research is needed to establish a clear link.

Probiotics: The gut microbiota's influence on overall health, including neurological conditions, has prompted research into the potential role of probiotics in ALS. While the exact mechanisms are not fully understood, maintaining a healthy gut microbiota through probiotics might have indirect effects on overall health. However, direct evidence linking probiotics to ALS prevention or treatment is lacking.