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🍽️ sulfachloropyridazine,(prescription)

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  1. Antibacterial Activity: Sulfachloropyridazine works by inhibiting the growth and reproduction of susceptible bacteria. It interferes with the synthesis of dihydrofolic acid in bacteria, which is essential for the production of nucleic acids and proteins required for bacterial growth. By disrupting folate metabolism, sulfachloropyridazine effectively kills or inhibits the growth of bacterial pathogens.

  2. Broad-Spectrum Antibiotic: Sulfachloropyridazine exhibits broad-spectrum antibacterial activity against a variety of gram-positive and gram-negative bacteria, including Escherichia coli, Salmonella spp., Pasteurella spp., and various respiratory and urinary tract pathogens in animals.

  3. Veterinary Use: Sulfachloropyridazine is commonly used in veterinary medicine for the treatment and prevention of bacterial infections in livestock, poultry, and other animals. It may be administered orally or parenterally (via injection) depending on the type and severity of the infection.

  4. Control of Bacterial Diseases: Sulfachloropyridazine is used to control and manage bacterial diseases in animals, including respiratory infections, enteric diseases, urinary tract infections, and systemic bacterial infections. It is often included in feed or water medication formulations for mass treatment of livestock populations.

  5. Dosage and Administration: The dosage and administration of sulfachloropyridazine vary depending on the species of animal being treated, the severity of the infection, and the formulation of the medication. It is important to follow the prescribing veterinarian's instructions carefully and administer the medication for the full duration of treatment to ensure effective bacterial eradication and prevent the development of antimicrobial resistance.

  6. Safety and Adverse Effects: While sulfachloropyridazine is generally considered safe when used appropriately in animals, adverse effects may occur, including allergic reactions, gastrointestinal disturbances (e.g., diarrhea, vomiting), and hypersensitivity reactions. In rare cases, sulfonamide antibiotics may cause more severe adverse effects such as hematological abnormalities (e.g., hemolytic anemia, thrombocytopenia) or skin reactions (e.g., dermatitis, photosensitivity).

  7. Drug Interactions: Sulfachloropyridazine may interact with other medications or substances, including other antibiotics, anticoagulants, diuretics, and anticonvulsants, among others. It is important to inform the prescribing veterinarian about any concurrent medications or medical conditions to avoid potential drug interactions or adverse effects.

  8. Regulatory Considerations: The use of sulfachloropyridazine in animals is subject to regulatory oversight and may require veterinary prescription or supervision in some jurisdictions. It is important to comply with local regulations and guidelines regarding the use of antimicrobial agents in animal healthcare to promote responsible antibiotic use and minimize the risk of antimicrobial resistance.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of sulfachloropyridazine,(prescription) On Probiotics

Rank Probiotic Impact
species Bacteroides uniformis Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
species Parabacteroides distasonis Reduces
species Streptococcus thermophilus Reduces

Bacteria Impacted by sulfachloropyridazine,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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πŸ““ Direct Citations πŸ‘ͺπŸ‘Ά Indirect Citations Taxonomy Rank Effect
0 1 Streptococcus genus Decreases
0 1 Bacteroides genus Decreases
0 1 Escherichia genus Decreases
0 1 Shigella genus Decreases
0 1 Fusobacterium genus Decreases
0 1 Parabacteroides genus Decreases
0 1 Eggerthella genus Decreases
0 1 Lacticaseibacillus genus Decreases
0 1 Mediterraneibacter genus Decreases
0 1 Escherichia coli O1:K1:H7 no rank Decreases
0 1 Escherichia coli O139:H1 no rank Decreases
0 1 Escherichia coli O141:H4 no rank Decreases
0 1 Escherichia coli O145:H34 no rank Decreases
0 1 Escherichia coli O15:H12 no rank Decreases
0 1 Escherichia coli O155:H21 no rank Decreases
0 1 Escherichia coli O158:H23 no rank Decreases
0 1 Escherichia coli O16:H48 no rank Decreases
0 1 Escherichia coli O170:H18 no rank Decreases
0 1 Escherichia coli O18ac:H14 no rank Decreases
0 1 Escherichia coli O19:H7 no rank Decreases
0 1 Escherichia coli O2:K1:H4 no rank Decreases
0 1 Escherichia coli O2:K1:H5 no rank Decreases
0 1 Escherichia coli O2:K1:H7 no rank Decreases
0 1 Escherichia coli O20:H12 no rank Decreases
0 1 Escherichia coli O25:H16 no rank Decreases
0 1 Escherichia coli O55:H7 no rank Decreases
0 1 Escherichia coli O68:H12 no rank Decreases
0 1 Escherichia coli O7:H15 no rank Decreases
0 1 Escherichia coli O78:H51 no rank Decreases
0 1 Escherichia coli O80:H26 no rank Decreases
0 1 Escherichia coli O84:H7 no rank Decreases
0 1 Escherichia coli O85:H1 no rank Decreases
0 1 Escherichia coli O103 serogroup Decreases
0 1 Escherichia coli O111 serogroup Decreases
0 1 Escherichia coli O119 serogroup Decreases
0 1 Escherichia coli O121 serogroup Decreases
0 1 Escherichia coli O145 serogroup Decreases
0 1 Escherichia coli O155 serogroup Decreases
0 1 Escherichia coli O157 serogroup Decreases
0 1 Escherichia coli O177 serogroup Decreases
0 1 Escherichia coli O26 serogroup Decreases
0 1 Escherichia coli O3 serogroup Decreases
0 1 Escherichia coli O43 serogroup Decreases
0 1 Escherichia coli O5 serogroup Decreases
0 1 Escherichia coli O78 serogroup Decreases
0 1 Escherichia coli O86 serogroup Decreases
0 1 Escherichia coli O91 serogroup Decreases
0 1 Escherichia coli H20 serotype Decreases
0 1 Escherichia coli O1:H42 serotype Decreases
0 1 Escherichia coli O1:HNT serotype Decreases
0 1 Escherichia coli O10:H32 serotype Decreases
0 1 Escherichia coli O10:K5(L):H4 serotype Decreases
0 1 Escherichia coli O100:H21 serotype Decreases
0 1 Escherichia coli O103:H11 serotype Decreases
0 1 Escherichia coli O103:H2 serotype Decreases
0 1 Escherichia coli O103:H25 serotype Decreases
0 1 Escherichia coli O104:H21 serotype Decreases
0 1 Escherichia coli O104:H4 serotype Decreases
0 1 Escherichia coli O111:H- serotype Decreases
0 1 Escherichia coli O111:H11 serotype Decreases
0 1 Escherichia coli O111:H8 serotype Decreases
0 1 Escherichia coli O111:NM serotype Decreases
0 1 Escherichia coli O112ab:H8 serotype Decreases
0 1 Escherichia coli O112ac:H19 serotype Decreases
0 1 Escherichia coli O113:H21 serotype Decreases
0 1 Escherichia coli O114:H49 serotype Decreases
0 1 Escherichia coli O118:H16 serotype Decreases
0 1 Escherichia coli O121:H19 serotype Decreases
0 1 Escherichia coli O121:H7 serotype Decreases
0 1 Escherichia coli O123:H11 serotype Decreases
0 1 Escherichia coli O125ac:K+:H10 serotype Decreases
0 1 Escherichia coli O126:H45 serotype Decreases
0 1 Escherichia coli O127:H27 serotype Decreases
0 1 Escherichia coli O127:H6 serotype Decreases
0 1 Escherichia coli O128:H2 serotype Decreases
0 1 Escherichia coli O128ac:H12 serotype Decreases
0 1 Escherichia coli O139:H28 serotype Decreases
0 1 Escherichia coli O145:H25 serotype Decreases
0 1 Escherichia coli O145:H28 serotype Decreases
0 1 Escherichia coli O145:NM serotype Decreases
0 1 Escherichia coli O146:H21 serotype Decreases
0 1 Escherichia coli O15:H18 serotype Decreases
0 1 Escherichia coli O150:H6 serotype Decreases
0 1 Escherichia coli O152:H23 serotype Decreases
0 1 Escherichia coli O153:H2 serotype Decreases
0 1 Escherichia coli O156:H25 serotype Decreases
0 1 Escherichia coli O157:H- serotype Decreases
0 1 Escherichia coli O157:H43 serotype Decreases
0 1 Escherichia coli O157:H7 serotype Decreases
0 1 Escherichia coli O157:NM serotype Decreases
0 1 Escherichia coli O16:H6 serotype Decreases
0 1 Escherichia coli O165:H25 serotype Decreases
0 1 Escherichia coli O167:H26 serotype Decreases
0 1 Escherichia coli O174:H2 serotype Decreases
0 1 Escherichia coli O174:H21 serotype Decreases
0 1 Escherichia coli O174:H8 serotype Decreases
0 1 Escherichia coli O176:H45 serotype Decreases
0 1 Escherichia coli O177:NM serotype Decreases
0 1 Escherichia coli O2:H6 serotype Decreases
0 1 Escherichia coli O2:K2:H1 serotype Decreases
0 1 Escherichia coli O25:H1 serotype Decreases
0 1 Escherichia coli O25:NM serotype Decreases
0 1 Escherichia coli O26:H1 serotype Decreases
0 1 Escherichia coli O26:H11 serotype Decreases
0 1 Escherichia coli O28ac:NM serotype Decreases
0 1 Escherichia coli O29:H4 serotype Decreases
0 1 Escherichia coli O32:H37 serotype Decreases
0 1 Escherichia coli O39:NM serotype Decreases
0 1 Escherichia coli O44:H18 serotype Decreases
0 1 Escherichia coli O45:H2 serotype Decreases
0 1 Escherichia coli O6:H16 serotype Decreases
0 1 Escherichia coli O6:H16:CFA/II serotype Decreases
0 1 Escherichia coli O6:K2:H1 serotype Decreases
0 1 Escherichia coli O69:H11 serotype Decreases
0 1 Escherichia coli O7:H4 serotype Decreases
0 1 Escherichia coli O7:K1 serotype Decreases
0 1 Escherichia coli O78:H12 serotype Decreases
0 1 Escherichia coli O78:H4 serotype Decreases
0 1 Escherichia coli O79:H7 serotype Decreases
0 1 Escherichia coli O8:H8 serotype Decreases
0 1 Escherichia coli O81:NM serotype Decreases
0 1 Escherichia coli O83:H1 serotype Decreases
0 1 Escherichia coli O86:H34 serotype Decreases
0 1 Escherichia coli O89m:H10 serotype Decreases
0 1 Escherichia coli O89m:H9 serotype Decreases
0 1 Escherichia coli O9:H10 serotype Decreases
0 1 Escherichia coli O91:H14 serotype Decreases
0 1 Escherichia coli O91:NM serotype Decreases
0 1 Escherichia coli O99:H6 serotype Decreases
0 1 Escherichia coli ONT:H33 serotype Decreases
1 0 Bacteroides thetaiotaomicron species Decreases
1 0 Bacteroides uniformis species Decreases
1 0 Streptococcus salivarius species Decreases
1 0 Escherichia coli species Decreases
0 1 Streptococcus sp. FDAARGOS_192 species Decreases
1 0 Bacteroides fragilis species Decreases
1 0 Parabacteroides merdae species Decreases
1 0 Fusobacterium nucleatum species Decreases
0 1 Bacteroides humanifaecis species Decreases
0 1 Shigella dysenteriae species Decreases
0 1 Shigella flexneri species Decreases
0 1 Escherichia albertii species Decreases
0 1 Bacteroides sp. A1C1 species Decreases
0 1 Streptococcus vestibularis species Decreases
0 1 Bacteroides sp. CACC 737 species Decreases
0 1 Escherichia fergusonii species Decreases
0 1 Streptococcus parasanguinis species Decreases
1 0 Eggerthella lenta species Decreases
0 1 Streptococcus sp. LPB0220 species Decreases
0 1 Streptococcus sp. HSISM1 species Decreases
0 1 Shigella boydii species Decreases
0 1 Bacteroides sp. HF-162 species Decreases
0 1 Streptococcus gordonii species Decreases
0 1 Streptococcus sp. oral taxon 061 species Decreases
0 1 Streptococcus australis species Decreases
0 1 Shigella sonnei species Decreases
0 1 Streptococcus lactarius species Decreases
0 1 Escherichia marmotae species Decreases
1 0 Parabacteroides distasonis species Decreases
0 1 Streptococcus oralis species Decreases
0 1 Escherichia sp. E4742 species Decreases
0 1 Streptococcus sp. Marseille-Q6470 species Decreases
0 1 Streptococcus sp. oral taxon 431 species Decreases
0 1 Bacteroides luhongzhouii species Decreases
0 1 Streptococcus infantis species Decreases
0 1 Bacteroides faecium species Decreases
0 1 Streptococcus sanguinis species Decreases
0 1 Streptococcus ilei species Decreases
0 1 Streptococcus thermophilus species Decreases
1 0 Bacteroides caccae species Decreases
1 0 Lacticaseibacillus paracasei species Decreases
1 0 Mediterraneibacter gnavus species Decreases
0 1 Fusobacterium nucleatum subsp. nucleatum subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases
0 1 Lacticaseibacillus paracasei subsp. tolerans subspecies Decreases

Impact of sulfachloropyridazine,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.6 0.6
ADHD 1.3 0.1 12
Age-Related Macular Degeneration and Glaucoma 0.1 -0.1
Allergic Rhinitis (Hay Fever) 1.1 1.1 0
Allergies 1.9 0.5 2.8
Allergy to milk products 0.8 0.7 0.14
Alopecia (Hair Loss) 0.1 0.1
Alzheimer's disease 2.5 1.6 0.56
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.9 0.5 0.8
Ankylosing spondylitis 1.8 0.5 2.6
Anorexia Nervosa 0.5 1.2 -1.4
Antiphospholipid syndrome (APS) 1.5 1.5
Asthma 2.7 0.7 2.86
Atherosclerosis 1.5 1.5
Atrial fibrillation 1.3 0.9 0.44
Autism 2.2 2.6 -0.18
Autoimmune Disease 0.8 0.8
Barrett esophagus cancer 0.2 0.4 -1
benign prostatic hyperplasia 0.4 0.3 0.33
Biofilm 1.6 1.6
Bipolar Disorder 1 0.1 9
Brain Trauma 0.4 0.3 0.33
Breast Cancer 0.9 0.9
Cancer (General) 0.2 0.2 0
Carcinoma 1.7 0.4 3.25
Celiac Disease 1.7 0.4 3.25
Cerebral Palsy 0.7 0.3 1.33
Chronic Fatigue Syndrome 2.3 1.2 0.92
Chronic Kidney Disease 1 1
Chronic Lyme 0.3 -0.3
Chronic Obstructive Pulmonary Disease (COPD) 2.1 0.5 3.2
Chronic Urticaria (Hives) 1.2 0.5 1.4
Coagulation / Micro clot triggering bacteria 1.5 0.4 2.75
Cognitive Function 0.8 0.4 1
Colorectal Cancer 3.9 0.8 3.88
Constipation 0.7 0.7
Coronary artery disease 1.4 0.8 0.75
COVID-19 4.2 2.6 0.62
Crohn's Disease 3.9 1.1 2.55
Cushing's Syndrome (hypercortisolism) 0.3 -0.3
cystic fibrosis 0.8 0.3 1.67
d-lactic acidosis (one form of brain fog) 0.5 0.5
deep vein thrombosis 1.8 0.7 1.57
Denture Wearers Oral Shifts 1.3 1.3
Depression 3.8 1.7 1.24
Dermatomyositis 0.4 0.4
Eczema 1 1.5 -0.5
Endometriosis 1.8 0.5 2.6
Eosinophilic Esophagitis 0.2 0.4 -1
Epilepsy 2.3 0.8 1.87
erectile dysfunction 0.9 0.9
Fibromyalgia 0.6 0.9 -0.5
Functional constipation / chronic idiopathic constipation 2.3 0.9 1.56
gallstone disease (gsd) 1.4 0.2 6
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1 0.4 1.5
Generalized anxiety disorder 1.9 0.7 1.71
Glioblastoma 0.4 -0.4
Gout 0.7 0.2 2.5
Graves' disease 0.4 0.7 -0.75
Gulf War Syndrome 0.4 1.1 -1.75
Halitosis 1.2 0.4 2
Hashimoto's thyroiditis 1 0.3 2.33
Heart Failure 2.2 2.2
hemorrhagic stroke 0.3 0.3
Hidradenitis Suppurativa 0.8 0.8
High Histamine/low DAO 0.5 0.5
hypercholesterolemia (High Cholesterol) 0.5 0.5
hyperglycemia 1.7 0.4 3.25
hypertension (High Blood Pressure 1.6 1.8 -0.13
Hypothyroidism 0.1 -0.1
Hypoxia 0.4 0.4
IgA nephropathy (IgAN) 1.1 1.2 -0.09
Inflammatory Bowel Disease 4.1 2.1 0.95
Insomnia 1.3 0.7 0.86
Intelligence 1.5 1.5
Intracranial aneurysms 0.6 0.6
Irritable Bowel Syndrome 3.1 1.4 1.21
ischemic stroke 1.3 0.7 0.86
Liver Cirrhosis 3 1.4 1.14
Long COVID 2 1.2 0.67
Lung Cancer 0.5 0.5
Lymphoma 0.4 0.4
Mast Cell Issues / mastitis 1.2 1.2
ME/CFS with IBS 0.4 0.3 0.33
ME/CFS without IBS 0.7 0.4 0.75
membranous nephropathy 0.4 0.4
Menopause 0.4 0.4
Metabolic Syndrome 2.6 2.1 0.24
Mood Disorders 3.4 1.8 0.89
multiple chemical sensitivity [MCS] 1.1 1.1
Multiple Sclerosis 2.3 1.4 0.64
Multiple system atrophy (MSA) 0.2 0.2
myasthenia gravis 0.8 0.8
neuropathic pain 0.1 0.4 -3
Neuropathy (all types) 0.5 0.4 0.25
neuropsychiatric disorders (PANDAS, PANS) 0.9 0.9
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.8 0.3 5
NonCeliac Gluten Sensitivity 0.4 0.3 0.33
Obesity 2 2.5 -0.25
obsessive-compulsive disorder 2.7 0.7 2.86
Osteoarthritis 1.5 0.7 1.14
Osteoporosis 0.8 0.7 0.14
pancreatic cancer 0.7 0.4 0.75
Parkinson's Disease 3.1 1.7 0.82
Polycystic ovary syndrome 2.4 0.7 2.43
Premenstrual dysphoric disorder 0.1 -0.1
primary biliary cholangitis 0.4 1.1 -1.75
Primary sclerosing cholangitis 1.2 0.3 3
Psoriasis 1.4 0.5 1.8
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1.7 1 0.7
Schizophrenia 1.9 0.4 3.75
scoliosis 0.5 0.5
Sjögren syndrome 0.9 1 -0.11
Sleep Apnea 0.3 0.4 -0.33
Slow gastric motility / Gastroparesis 0.8 0.8
Small Intestinal Bacterial Overgrowth (SIBO) 1.4 1.4
Stress / posttraumatic stress disorder 1.3 0.6 1.17
Systemic Lupus Erythematosus 2 2
Tic Disorder 0.4 0.4
Tourette syndrome 0.4 0.3 0.33
Type 1 Diabetes 1.6 0.7 1.29
Type 2 Diabetes 2.6 3.2 -0.23
Ulcerative colitis 2.6 2.1 0.24
Unhealthy Ageing 1.8 0.1 17
Vitiligo 1.3 0.1 12

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