Spirochaetota: NCBI 203691, [phylum]

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| Spirochaetae| Spirochaetaeota| Spirochaetaeota Oren et al. 2015| Spirochaetes| Spirochaetes Garrity and Holt 2001| Spirochaetota

1. Pathogenic Spirochetes: Some spirochetes are known pathogens that can cause diseases in humans and animals. Notable examples include Treponema pallidum, the causative agent of syphilis, and Borrelia burgdorferi, which is associated with Lyme disease.

2. Gut Microbiota: Certain spirochetes are part of the natural microbial communities in the gastrointestinal tracts of animals, including humans. In the gut, they can contribute to the complex ecosystem and may play roles in fermentation and other metabolic processes.

3. Syphilis: Treponema pallidum is the spirochete responsible for syphilis, a sexually transmitted infection. Syphilis can progress through various stages and, if left untreated, may lead to severe health complications affecting multiple organ systems.

4. Lyme Disease: Borrelia burgdorferi is a spirochete transmitted by ticks and is responsible for Lyme disease. Lyme disease can cause a range of symptoms, including fever, fatigue, joint pain, and neurological symptoms. Early detection and treatment are crucial for managing Lyme disease.

5. Other Spirochetes: Spirochetes with non-pathogenic roles can be found in various environments, including aquatic habitats and soils. Some contribute to nutrient cycling and ecological processes.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Spirochaetota impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.4556739926338196	0.6692729592323303	Acidobacteriota	Parent Taxa
0.3638834059238434	0.6561981439590454	Bacillota	Parent Taxa
0.2994020879268646	0.5127696394920349	Planctomycetota	Parent Taxa
0.2751546800136566	0.5320607423782349	Gemmatimonadota	Parent Taxa
0.2658235728740692	0.5391797423362732	Mycoplasmatota	Parent Taxa

Other bacteria of the same rank impacting Spirochaetota

R2	Slope	Tax Name	Parent Chart
0.3180831968784332	0.523716926574707	Bacillota	Parent Taxa