Phocaeicola dorei: NCBI 357276, [species]

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| Bacteroides dorei| Bacteroides dorei Bakir et al. 2006 emend. Hahnke et al. 2016| Bacteroides sp. 175T| Bacteroides sp. 219| DSM 17855| JCM 13471| strain 175

1. Anti-inflammatory Effects:

   • Parabacteroides distasonis has been associated with anti-inflammatory properties. It is reported to produce molecules that can suppress inflammation in the gut. This anti-inflammatory potential may have implications for conditions characterized by chronic inflammation, such as inflammatory bowel disease (IBD) or other inflammatory disorders.

2. Metabolism and Short-Chain Fatty Acid Production:

   • Like many bacteria in the gut, Parabacteroides distasonis is involved in the fermentation of dietary fibers, leading to the production of short-chain fatty acids (SCFAs). SCFAs, particularly butyrate, have been linked to various health benefits, including maintaining the health of the intestinal epithelium and influencing metabolism.

3. Immunomodulation:

   • Research suggests that Parabacteroides distasonis may have immunomodulatory effects, influencing the activity of the immune system. This can be important for maintaining a balanced immune response and preventing excessive inflammation.

4. Association with a Healthy Gut Microbiota:

   • Parabacteroides distasonis is often found in individuals with a diverse and healthy gut microbiota. A diverse microbiota is generally considered beneficial for overall gut health and is associated with a lower risk of certain health conditions.

5. Butyrate Production:

   • Some strains of Parabacteroides distasonis have been identified as producers of butyrate. Butyrate is known for its role in providing energy to the cells lining the colon and promoting gut health.

6. Potential in Gut Dysbiosis:

   • Some studies suggest that alterations in the abundance of Parabacteroides distasonis may be associated with conditions involving gut dysbiosis, such as inflammatory bowel disease or irritable bowel syndrome. Understanding the dynamics of this species in the context of gut health is an area of ongoing research.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Phocaeicola dorei impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.22811287641525269	0.47703877091407776	Bacteroides salyersiae	Parent Taxa
0.21021698415279388	0.4556621313095093	Bacteroides caecimuris	Parent Taxa
0.18647591769695282	0.4318440854549408	Bacteroides uniformis	Parent Taxa
0.17346957325935364	0.4107375741004944	Bacteroides luhongzhouii	Parent Taxa
0.16490016877651215	0.35625386238098145	Parabacteroides faecis	Parent Taxa
0.16392093896865845	0.3994235098361969	Bacteroides humanifaecis	Parent Taxa
0.1584118902683258	0.390078604221344	Bacteroides faecium	Parent Taxa
0.15578509867191315	0.3903634548187256	Bacteroides sp. A1C1	Parent Taxa
0.15244121849536896	0.39043766260147095	Bacteroides thetaiotaomicron	Parent Taxa
0.1506725251674652	0.35961371660232544	Bacteroides helcogenes	Parent Taxa
0.14926806092262268	0.38129541277885437	Bacteroides sp. CACC 737	Parent Taxa
0.1472652107477188	0.3830886781215668	Bacteroides eggerthii	Parent Taxa
0.14159348607063293	0.3762815296649933	Parabacteroides distasonis	Parent Taxa
0.14111630618572235	0.37563377618789673	Bacteroides ovatus	Parent Taxa
0.139859139919281	0.3739297389984131	Bacteroides xylanisolvens	Parent Taxa
0.13827137649059296	0.3653881549835205	Parabacteroides johnsonii	Parent Taxa
0.1373504400253296	0.36615660786628723	Bacteroides sp. D2	Parent Taxa
0.1322057992219925	0.34661945700645447	Barnesiella viscericola	Parent Taxa
0.13032746315002441	0.3434969186782837	Coprobacter fastidiosus	Parent Taxa
0.12868356704711914	0.3432447910308838	Coprobacter secundus	Parent Taxa
0.12859559059143066	0.3537779152393341	Phocaeicola salanitronis	Parent Taxa
0.1261206418275833	0.3512360751628876	Bacteroides sp. M10	Parent Taxa
0.12543317675590515	0.3484449088573456	Bacteroides sp. DH3716P	Parent Taxa
0.12239719182252884	0.34501588344573975	Bacteroides sp. HF-162	Parent Taxa
0.11224890500307083	0.3069781959056854	Parabacteroides sp. CT06	Parent Taxa
0.11109814047813416	0.33060726523399353	Bacteroides zhangwenhongii	Parent Taxa
0.10980329662561417	0.33117061853408813	Bacteroides faecis	Parent Taxa
0.10173220187425613	0.3189469575881958	Bacteroides caccae	Parent Taxa

Other bacteria of the same rank impacting Phocaeicola dorei

R2	Slope	Tax Name	Parent Chart
0.22811287641525269	0.47818517684936523	Bacteroides salyersiae	Parent Taxa
0.21021698415279388	0.46134400367736816	Bacteroides caecimuris	Parent Taxa
0.18647591769695282	0.4318130612373352	Bacteroides uniformis	Parent Taxa
0.17346957325935364	0.42233675718307495	Bacteroides luhongzhouii	Parent Taxa
0.16490016877651215	0.4628726541996002	Parabacteroides faecis	Parent Taxa
0.16392093896865845	0.4103938341140747	Bacteroides humanifaecis	Parent Taxa
0.1584118902683258	0.4061024785041809	Bacteroides faecium	Parent Taxa
0.15578509867191315	0.39907705783843994	Bacteroides sp. A1C1	Parent Taxa
0.15244121849536896	0.3904367685317993	Bacteroides thetaiotaomicron	Parent Taxa
0.1506725251674652	0.41898438334465027	Bacteroides helcogenes	Parent Taxa
0.14926806092262268	0.3914761543273926	Bacteroides sp. CACC 737	Parent Taxa
0.1472652107477188	0.3844154477119446	Bacteroides eggerthii	Parent Taxa
0.14159348607063293	0.3762966990470886	Parabacteroides distasonis	Parent Taxa
0.14111630618572235	0.3756752610206604	Bacteroides ovatus	Parent Taxa
0.139859139919281	0.3740251660346985	Bacteroides xylanisolvens	Parent Taxa
0.13827137649059296	0.378423273563385	Parabacteroides johnsonii	Parent Taxa
0.1373504400253296	0.37511390447616577	Bacteroides sp. D2	Parent Taxa
0.1322057992219925	0.38141483068466187	Barnesiella viscericola	Parent Taxa
0.13032746315002441	0.37941378355026245	Coprobacter fastidiosus	Parent Taxa
0.12868356704711914	0.3749031722545624	Coprobacter secundus	Parent Taxa
0.12859559059143066	0.3634924292564392	Phocaeicola salanitronis	Parent Taxa
0.1261206418275833	0.3590765595436096	Bacteroides sp. M10	Parent Taxa
0.12543317675590515	0.35997992753982544	Bacteroides sp. DH3716P	Parent Taxa
0.12239719182252884	0.3547581136226654	Bacteroides sp. HF-162	Parent Taxa
0.11224890500307083	0.3656575679779053	Parabacteroides sp. CT06	Parent Taxa
0.11109814047813416	0.3360426425933838	Bacteroides zhangwenhongii	Parent Taxa
0.10980329662561417	0.3315611183643341	Bacteroides faecis	Parent Taxa
0.10173220187425613	0.31896278262138367	Bacteroides caccae	Parent Taxa