Lacticaseibacillus rhamnosus: NCBI 47715, [species]

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| ATCC 7469| CCUG 21452| CIP A157| DSM 20021| IFO 3425| JCM 1136| Lactobacillus casei rhamnosus| Lactobacillus casei subsp. rhamnosus| Lactobacillus casei subsp. rhamnosus Hansen 1968 (Approved Lists 1980)| Lactobacillus rhamnosus| Lactobacillus rhamnosus (Hansen 1968) Collins et al. 1989| Lactobacillus sp. NCIM 2587| Lactobacillus sp. W6| Lactobacillus sp. X9| LMG 6400| LMG:6400| NBRC 3425| NCAIM B.01147| NCCB 46033| NCDO 243| NCIMB 6375| NCTC 12953| NRRL B-442| VKM B-574

1. Gut health: Lacticaseibacillus rhamnosus is known for its beneficial effects on gut health. It can help maintain a healthy balance of gut microbiota by competing with harmful bacteria for resources and adhering to the intestinal lining, thereby reducing the colonization of pathogenic bacteria. This can contribute to improved digestion, reduced gastrointestinal discomfort, and enhanced overall gut function.

2. Immune modulation: Lacticaseibacillus rhamnosus has been shown to modulate the immune system, particularly in the gut-associated lymphoid tissue (GALT). It can stimulate the production of anti-inflammatory cytokines and regulatory immune cells, while also enhancing the activity of immune cells involved in defense against pathogens. This immune modulation may help reduce the risk of infections and allergic reactions, as well as support immune function in individuals with autoimmune conditions.

3. Prevention and treatment of gastrointestinal disorders: Lacticaseibacillus rhamnosus supplementation has been studied for its potential to prevent and alleviate various gastrointestinal disorders, such as diarrhea, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and antibiotic-associated diarrhea. It may help restore gut microbial balance, reduce intestinal inflammation, strengthen the gut barrier function, and alleviate symptoms associated with these conditions.

4. Women's health: Lacticaseibacillus rhamnosus has been investigated for its role in supporting women's health, particularly in preventing and treating urogenital infections such as bacterial vaginosis and urinary tract infections (UTIs). By colonizing the vaginal and urinary tracts, Lacticaseibacillus rhamnosus can inhibit the growth of pathogenic bacteria, maintain a lower pH environment, and prevent the adherence of pathogens to epithelial cells.

5. Allergy prevention: Some studies suggest that early exposure to Lacticaseibacillus rhamnosus during infancy may help reduce the risk of developing allergic conditions, such as eczema, asthma, and food allergies. It is thought that the probiotic's immunomodulatory effects and its ability to strengthen the gut barrier may play a role in preventing allergic sensitization and promoting immune tolerance.

6. Mental health: Emerging research indicates that the gut microbiota, including species like Lacticaseibacillus rhamnosus, may influence brain function and mental health through the gut-brain axis. While more studies are needed, preliminary evidence suggests that probiotics, including Lacticaseibacillus rhamnosus, may have potential benefits for mood regulation, stress management, and cognitive function.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Lacticaseibacillus rhamnosus impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.18450242280960083	0.5929657816886902	Bifidobacterium breve	Parent Taxa
0.18041491508483887	0.4434501826763153	Lacticaseibacillus paracasei	Parent Taxa
0.11964982002973557	0.3588123917579651	Staphylococcus epidermidis	Parent Taxa
0.11436280608177185	-0.4009692370891571	Campylobacter jejuni	Parent Taxa
0.10356251150369644	-0.4049825370311737	Campylobacter coli	Parent Taxa

Other bacteria of the same rank impacting Lacticaseibacillus rhamnosus

R2	Slope	Tax Name	Parent Chart
0.18450242280960083	0.3111518919467926	Bifidobacterium breve	Parent Taxa
0.18041491508483887	0.40684372186660767	Lacticaseibacillus paracasei	Parent Taxa
0.11964982002973557	0.33346065878868103	Staphylococcus epidermidis	Parent Taxa
0.11436280608177185	-0.28521591424942017	Campylobacter jejuni	Parent Taxa
0.10356251150369644	-0.25572091341018677	Campylobacter coli	Parent Taxa