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Methanobacteriales Details: NCBI 2158, gram-negative or unknown [order]

| Methanobacteriales| Methanobacteriales Balch and Wolfe 1981

  1. Methane Production in the Gut: Methanobacteriales are commonly found in the gastrointestinal tract of humans and other animals. They play a role in the final stages of anaerobic digestion, where they convert hydrogen and carbon dioxide produced by other microorganisms into methane. Methane production in the gut is a normal part of microbial fermentation during digestion.

  2. Association with Gut Microbiota: Methanogenic archaea, including those in the order Methanobacteriales, are part of the complex community of microorganisms in the human gut microbiota. The gut microbiota plays a crucial role in various aspects of health, including digestion, metabolism, and immune function.

  3. Hydrogen Removal: Methanobacteriales contribute to the removal of hydrogen produced by other microbes in the gut during the fermentation of dietary fibers and other compounds. This process, known as methanogenesis, helps maintain a favorable environment for the activities of other microorganisms involved in the fermentation process.

  4. Associations with Gastrointestinal Conditions: Elevated levels of methane in the breath have been associated with certain gastrointestinal conditions. For example, some studies suggest a potential correlation between increased methane production and conditions like constipation-predominant irritable bowel syndrome (IBS-C). However, the relationship between methane levels and specific health conditions is complex and may vary among individuals.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Statistics NCBI Data Punk End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Methanobacteriales

These are values that are computed from lab specific samples and are in percentage
Lab Frequency Average Median Minimum Maximum Std.Dev. Skew 25 - 75 Percentile 5 - 95 Percentile Lab Ranges Box-Plot-Whiskers Harmonic Mean Geometric Mean Obs.
AmericanGut 0.6 0.107 0.0246 0.0068 0.6178 0.1992 1.2415   0.0127 - 0.0601   0.0081 - 0.4431   -0.2814 - 0.4955   -0.0584 - 0.1312 0.0183 0.0345 9
BiomeSight 0.244 0.1149 0.025 0.001 8.192 0.401 0.6722   0.006 - 0.0859   0.001 - 0.4357   -0.6672 - 0.8969   -0.1138 - 0.2057 0.0064 0.0234 904
BiomeSightRdp 0.2593 0.1471 0.008 0.001 0.808 0.2992 1.3952   0.003 - 0.1035   0.001 - 0.622   -0.4363 - 0.7306   -0.1477 - 0.2542 0.0029 0.0142 7
custom 0.4043 1.0709 1.6279 0.0001 1.778 0.8033 -2.0801   0.1247 - 1.778   0.0009 - 1.778   -0.4956 - 2.6374   -2.3553 - 4.258 0.0016 0.2238 19
es-xenogene 0.6818 3.9311 0.003 0.001 54.39 13.9878 0.8425   0.002 - 0.23   0.001 - 18.7713   -23.345 - 31.2073   -0.34 - 0.572 0.0027 0.02 15
Thorne 0.6508 0.0344 0.0005 0.0001 0.7964 0.1212 0.8376   0.0004 - 0.0009   0.0002 - 0.2577   -0.2021 - 0.2708   -0.0004 - 0.0018 0.0005 0.0011 123
Thryve 0.2081 0.3325 0.0655 0.0001 5.1563 0.7033 1.139   0.0041 - 0.2515   0.0012 - 1.7541   -1.0388 - 1.7038   -0.367 - 0.6227 0.0041 0.0438 258
uBiome 0.2776 1.2867 0.6408 0.0021 8.6169 1.5842 1.2231   0.1551 - 1.9306   0.0081 - 4.3474   -1.8025 - 4.3759   -2.5082 - 4.594 0.0449 0.4218 219
Vitract 0.236 0.0012 0.0012 0.0012 0.0012 0   0.0012 - 0.0012   0.0012 - 0.0012   -   0.0012 - 0.0012 0.2268 0.0012 189

External Reference Ranges for Methanobacteriales

Methanobacteriales (NCBI 2158) per million
Source of Ranges Low Boundary High Boundary Low Boundary %age High Boundary %age
PrecisionBiome 3.384882802492939E-05 0.24859590828418732 0 0
Thorne (20/80%ile) 3.5 199.6 0.0004 0.02

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Data Contradictions — Limits of Certainity

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