Spirochaetales: NCBI 136, [order]

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| Spirochaetales| Spirochaetales Buchanan 1917 (Approved Lists 1980) emend. Gupta et al. 2013| spirochetes

1. Pathogenic Spirochetes:

   • Some spirochetes within the order Spirochaetales are known to be pathogenic and can cause diseases in humans and animals. Notable examples include:
     • Borrelia burgdorferi: Causes Lyme disease, which is transmitted through the bite of infected ticks.
     • Treponema pallidum: Causes syphilis, a sexually transmitted infection.
     • Leptospira spp.: Cause leptospirosis, a bacterial infection that can be transmitted through contact with contaminated water or soil.

2. Commensal and Environmental Spirochetes:

   • Not all spirochetes within the order Spirochaetales are pathogenic. Some are part of the normal microbial flora in the gastrointestinal tracts of animals, including humans, and contribute to various ecological processes.

3. Lyme Disease:

   • Lyme disease, caused by Borrelia burgdorferi and transmitted by ticks, is a well-known spirochetal infection. It can lead to symptoms such as fever, fatigue, joint pain, and skin rashes. If left untreated, Lyme disease can progress to more severe complications.

4. Syphilis:

   • Treponema pallidum, the spirochete responsible for syphilis, can cause a range of symptoms, including sores, rashes, and systemic involvement. If not treated, syphilis can progress to more serious stages affecting multiple organs.

5. Leptospirosis:

   • Leptospirosis, caused by various Leptospira species, can lead to flu-like symptoms and, in severe cases, affect the liver, kidneys, and other organs. It is often associated with exposure to water or soil contaminated with the urine of infected animals.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Spirochaetales impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.4556359052658081	0.7355180382728577	Eubacteriales	Parent Taxa
0.3775275647640228	0.5800940990447998	Rhodospirillales	Parent Taxa
0.3241928815841675	0.5082873106002808	Myxococcales	Parent Taxa
0.3207409083843231	0.5372722744941711	Nostocales	Parent Taxa
0.31156811118125916	0.5736591219902039	Acholeplasmatales	Parent Taxa
0.2924982011318207	0.48720046877861023	Micromonosporales	Parent Taxa
0.25290679931640625	0.4916050136089325	Mycoplasmoidales	Parent Taxa
0.25246191024780273	0.4789406359195709	Gemmatimonadales	Parent Taxa

Other bacteria of the same rank impacting Spirochaetales

R2	Slope	Tax Name	Parent Chart
0.3866129219532013	0.6906533241271973	Rhodospirillales	Parent Taxa
0.3564850687980652	0.548761248588562	Eubacteriales	Parent Taxa