Treponema: NCBI 157, [genus]

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| "Microspironema" Stiles and Pfender 1905| "Spironema" Vuillemin 1905| Microspironema| Treponema| Treponema Schaudinn 1905| Treponema Schaudinn 1905 emend Abt et al. 2013

1. Syphilis (Treponema pallidum):

   • Treponema pallidum is a spirochete bacterium that causes syphilis, a sexually transmitted infection (STI). Syphilis progresses through various stages, including primary, secondary, latent, and tertiary stages. It can affect multiple organ systems and lead to a range of symptoms, including genital sores, skin rashes, fever, and, if left untreated, more severe complications affecting the cardiovascular and nervous systems.

2. Treponemal Infections:

   • Apart from T. pallidum, other treponemes may cause various conditions in animals and humans. Some treponemes are associated with oral infections, such as periodontal disease. Treponemes in the oral cavity are often part of the complex microbial community, and their role in periodontal health and disease is an area of ongoing research.

3. Spirochete Characteristics:

   • Treponema bacteria are characterized by their spiral or corkscrew shape and are motile, often using endoflagella (axial filaments) for movement. These unique characteristics contribute to their ability to invade tissues and evade the host immune response.

4. Transmission:

   • Syphilis is primarily transmitted through sexual contact, including vaginal, anal, and oral sex. Vertical transmission from mother to child during pregnancy is also possible.

5. Diagnosis and Treatment:

   • Diagnosis of syphilis often involves serological tests to detect antibodies against Treponema pallidum. Syphilis is typically treated with antibiotics such as penicillin, which is effective in curing the infection at various stages.

6. Prevention:

   • Prevention of syphilis involves practicing safe sex, using barrier methods (such as condoms), and getting tested regularly, especially for individuals at higher risk of infection.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Treponema impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.5330787897109985	0.7940320372581482	Anaerobutyricum	Parent Taxa
0.5255714654922485	0.7872096300125122	Dorea	Parent Taxa
0.51216721534729	0.7779058814048767	Coprococcus	Parent Taxa
0.478434681892395	0.7347532510757446	Subdoligranulum	Parent Taxa
0.46333184838294983	0.7181602716445923	Wansuia	Parent Taxa
0.4316396117210388	0.702056348323822	Faecalitalea	Parent Taxa
0.4246964156627655	0.6522794365882874	Vallitalea	Parent Taxa
0.42306429147720337	0.7080806493759155	Blautia	Parent Taxa
0.4116029441356659	0.6789560317993164	Butyrivibrio	Parent Taxa
0.40693041682243347	0.6902130842208862	Ruminococcus	Parent Taxa
0.40085670351982117	0.6865370273590088	Eubacterium	Parent Taxa
0.39636385440826416	0.6501489877700806	Massilistercora	Parent Taxa
0.38759103417396545	0.6726456880569458	Vescimonas	Parent Taxa
0.38700446486473083	0.6400372385978699	Christensenella	Parent Taxa
0.3759792745113373	0.6381444334983826	Marvinbryantia	Parent Taxa
0.37130194902420044	0.6640082001686096	Anaerostipes	Parent Taxa
0.3639308512210846	0.6308625340461731	Ligilactobacillus	Parent Taxa
0.3533836901187897	0.5498893857002258	Komagataeibacter	Parent Taxa
0.34775689244270325	0.6245128512382507	Candidatus Phytoplasma	Parent Taxa
0.34577253460884094	0.6383275389671326	Clostridioides	Parent Taxa
0.3453139662742615	0.6400346159934998	Roseburia	Parent Taxa
0.33881932497024536	0.6008609533309937	Catenibacterium	Parent Taxa
0.33598119020462036	0.6670922040939331	Sodalis	Parent Taxa
0.3321109712123871	0.5104010105133057	Brevibacillus	Parent Taxa
0.3285467326641083	0.6122164130210876	Intestinimonas	Parent Taxa
0.326262891292572	0.5700241923332214	Pseudoalteromonas	Parent Taxa
0.3262239396572113	0.6111130714416504	Lawsonibacter	Parent Taxa
0.32183143496513367	0.6141983270645142	Ruthenibacterium	Parent Taxa
0.32177165150642395	0.5695344805717468	Novisyntrophococcus	Parent Taxa
0.318135142326355	0.6085361242294312	Lachnoclostridium	Parent Taxa
0.31071242690086365	0.5587477684020996	Qiania	Parent Taxa
0.3102227747440338	0.5992345213890076	Anaerotruncus	Parent Taxa
0.30921825766563416	0.5532236695289612	Lacrimispora	Parent Taxa
0.3070816695690155	0.5732700824737549	Lachnoanaerobaculum	Parent Taxa
0.3057571053504944	0.5768767595291138	Longicatena	Parent Taxa
0.3057349622249603	0.5373397469520569	Rodentibacter	Parent Taxa
0.3045039176940918	0.588714063167572	Adlercreutzia	Parent Taxa
0.3041142523288727	0.5878317952156067	Faecalibacillus	Parent Taxa
0.2980123460292816	0.5556302070617676	Solibaculum	Parent Taxa
0.29708126187324524	0.5719977617263794	Globicatella	Parent Taxa
0.2970743179321289	0.534366250038147	Maliibacterium	Parent Taxa
0.29070937633514404	0.5659348368644714	Oscillibacter	Parent Taxa
0.28643423318862915	0.5057348012924194	Coriobacterium	Parent Taxa
0.2801792621612549	0.5768041610717773	Clostridium	Parent Taxa
0.27978459000587463	0.5088866353034973	Arthrobacter	Parent Taxa
0.27901777625083923	0.569888710975647	Lachnospira	Parent Taxa
0.27837175130844116	0.5632909536361694	Pusillibacter	Parent Taxa
0.27518942952156067	0.5716468691825867	Faecalibacterium	Parent Taxa
0.2691444456577301	0.5619258880615234	Simiaoa	Parent Taxa
0.2626391649246216	0.46947312355041504	Petrocella	Parent Taxa
0.25450649857521057	0.5122325420379639	Flintibacter	Parent Taxa
0.2502134144306183	0.4761354923248291	Exiguobacterium	Parent Taxa

Other bacteria of the same rank impacting Treponema

R2	Slope	Tax Name	Parent Chart
0.4218173921108246	0.5993659496307373	Anaerobutyricum	Parent Taxa
0.41785871982574463	0.5959489345550537	Dorea	Parent Taxa
0.4011196196079254	0.5850715637207031	Coprococcus	Parent Taxa
0.3998353183269501	0.6163326501846313	Wansuia	Parent Taxa
0.38813719153404236	0.6022517085075378	Subdoligranulum	Parent Taxa
0.37645265460014343	0.6904003620147705	Komagataeibacter	Parent Taxa
0.3749847114086151	0.6149008274078369	Massilistercora	Parent Taxa
0.36914172768592834	0.6217643022537231	Christensenella	Parent Taxa
0.3659680187702179	0.5810839533805847	Faecalitalea	Parent Taxa
0.3609609305858612	0.5975599884986877	Marvinbryantia	Parent Taxa
0.34280461072921753	0.6382549405097961	Maliibacterium	Parent Taxa
0.33926114439964294	0.5702511668205261	Butyrivibrio	Parent Taxa
0.3387415409088135	0.6126578450202942	Novisyntrophococcus	Parent Taxa
0.33761653304100037	0.6046393513679504	Qiania	Parent Taxa
0.3330870270729065	0.5753455758094788	Ligilactobacillus	Parent Taxa
0.32467564940452576	0.597743034362793	Lacrimispora	Parent Taxa
0.3222012221813202	0.574125349521637	Catenibacterium	Parent Taxa
0.3106389045715332	0.5687614679336548	Lachnoanaerobaculum	Parent Taxa
0.3056700825691223	0.5080179572105408	Blautia	Parent Taxa
0.3025408685207367	0.5675109028816223	Solibaculum	Parent Taxa
0.2995442748069763	0.5141901969909668	Ruminococcus	Parent Taxa
0.29086384177207947	0.5988949537277222	Intestinibaculum	Parent Taxa
0.28787678480148315	0.49776533246040344	Clostridium	Parent Taxa
0.28515589237213135	0.49613386392593384	Eubacterium	Parent Taxa
0.2769528031349182	0.5891322493553162	Mageeibacillus	Parent Taxa
0.27644386887550354	0.5253708362579346	Longicatena	Parent Taxa
0.27170971035957336	0.48726388812065125	Vescimonas	Parent Taxa
0.2580922245979309	0.5597991347312927	Parvimonas	Parent Taxa
0.2568063735961914	0.46806269884109497	Anaerostipes	Parent Taxa
0.25172629952430725	0.5450605154037476	Acutalibacter	Parent Taxa