Tannerella forsythia: NCBI 28112, [species]

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| ATCC 43037| Bacteroides forsythus| Bacteroides forsythus Tanner et al. 1986| CCUG 21028 A| CCUG 33064| CCUG 33226| CIP 105219| FDC 338| JCM 10827| Tannerella forsythensis| Tannerella forsythensis corrig. (Tanner et al. 1986) Sakamoto et al. 2002| Tannerella forsythia| Tannerella forsythia corrig. (Tanner et al. 1986) Sakamoto et al. 2002

1. Periodontal Disease:

   • Tannerella forsythia is one of the bacterial species commonly associated with periodontal disease, particularly chronic periodontitis. Periodontal diseases involve inflammation and infection of the gums, leading to the destruction of the supporting structures of the teeth.

2. Biofilm Formation:

   • Tannerella forsythia, along with other bacteria, contributes to the formation of dental plaque and biofilms on tooth surfaces. These biofilms play a role in the initiation and progression of periodontal disease.

3. Tissue Destruction:

   • In periodontitis, the immune response to the bacterial infection can lead to inflammation. Persistent inflammation may result in the destruction of the gingival tissues, connective tissue, and bone that support the teeth.

4. Association with Other Pathogens:

   • Periodontal diseases often involve a complex microbial community. Tannerella forsythia is frequently found in conjunction with other periodontal pathogens, such as Porphyromonas gingivalis and Treponema denticola.

5. Virulence Factors:

   • Tannerella forsythia possesses various virulence factors that contribute to its ability to evade the host immune response and promote the establishment of infections in periodontal tissues.

6. Systemic Health Implications:

   • There is ongoing research exploring potential links between periodontal disease and systemic health conditions, such as cardiovascular diseases and diabetes. However, the exact nature of these associations is still an area of scientific investigation.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Tannerella forsythia impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.11331803351640701	0.3358376622200012	Porphyromonas gingivalis	Parent Taxa

Other bacteria of the same rank impacting Tannerella forsythia

R2	Slope	Tax Name	Parent Chart
0.11331803351640701	0.3374190628528595	Porphyromonas gingivalis	Parent Taxa