Treponemataceae: NCBI 2845253, [family]

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1. Syphilis (Treponema pallidum):

   • Treponema pallidum is the causative agent of syphilis, a sexually transmitted infection (STI). Syphilis can progress through various stages, including primary, secondary, latent, and tertiary stages. It affects multiple organ systems and can lead to a range of symptoms, including genital sores, skin rashes, fever, and, if left untreated, more severe complications affecting the cardiovascular and nervous systems.

2. Oral Treponemes:

   • In addition to T. pallidum, other treponemes are commonly found in the oral cavity. These oral treponemes are part of the complex microbial community in the mouth and are typically associated with periodontal health and disease. Some species of oral treponemes may contribute to the development of periodontal disease.

3. Symbiotic and Saprophytic Species:

   • Many species within the genus Treponema are part of the normal microbial flora in various environments, including the digestive tracts of animals and humans. Some are commensal, living harmoniously with their host, while others are saprophytic, contributing to the decomposition of organic matter in soil and other environments.

4. Microbial Communities:

   • Treponemes are often found in complex microbial communities, where their interactions with other microorganisms and the host can influence the overall ecology and function of the community.

5. Research and Diversity:

   • The diversity within the genus Treponema is vast, and ongoing research aims to characterize and understand the various species within this group. While some species have clear pathogenic or symbiotic roles, the functions of others are still being explored.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Treponemataceae impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.4464785158634186	0.7284923791885376	Lachnospiraceae	Parent Taxa
0.4008893072605133	0.6865649819374084	Eubacteriaceae	Parent Taxa
0.387090802192688	0.640108585357666	Christensenellaceae	Parent Taxa
0.3736441135406494	0.6634040474891663	Erysipelotrichaceae	Parent Taxa
0.359021931886673	0.5575535893440247	Acetobacteraceae	Parent Taxa
0.35201388597488403	0.646852433681488	Oscillospiraceae	Parent Taxa
0.3408561050891876	0.6352537274360657	Peptostreptococcaceae	Parent Taxa
0.33799898624420166	0.607925534248352	Eubacteriales Family XIII. Incertae Sedis	Parent Taxa
0.33589500188827515	0.667070209980011	Bruguierivoracaceae	Parent Taxa
0.3262115716934204	0.5700770616531372	Pseudoalteromonadaceae	Parent Taxa
0.3111814856529236	0.5733624696731567	Acholeplasmataceae	Parent Taxa
0.297158807516098	0.5344385504722595	Maliibacteriaceae	Parent Taxa
0.29262205958366394	0.4889797866344452	Micromonosporaceae	Parent Taxa
0.27141767740249634	0.42492347955703735	Chromatiaceae	Parent Taxa
0.2690410017967224	0.46420469880104065	Rhodanobacteraceae	Parent Taxa
0.2604478597640991	0.494517058134079	Vallitaleaceae	Parent Taxa
0.25718361139297485	0.45628052949905396	Spirosomataceae	Parent Taxa
0.2521112859249115	0.47818297147750854	Gemmatimonadaceae	Parent Taxa
0.25061383843421936	0.484671950340271	Cytophagaceae	Parent Taxa

Other bacteria of the same rank impacting Treponemataceae

R2	Slope	Tax Name	Parent Chart
0.3794380724430084	0.6885274648666382	Acetobacteraceae	Parent Taxa
0.3692270517349243	0.6218361854553223	Christensenellaceae	Parent Taxa
0.3436148166656494	0.5396366119384766	Lachnospiraceae	Parent Taxa
0.34289106726646423	0.6383354663848877	Maliibacteriaceae	Parent Taxa
0.31187447905540466	0.5636367201805115	Eubacteriales Family XIII. Incertae Sedis	Parent Taxa
0.2851986587047577	0.49617186188697815	Eubacteriaceae	Parent Taxa
0.2581230401992798	0.4709412753582001	Erysipelotrichaceae	Parent Taxa