Parabacteroides distasonis: NCBI 823, [species]

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| "Bacteroides fragilis subsp. distasonis" (Eggerth and Gagnon 1933) Holdeman and Moore 1970| "Pseudobacterium distasonis" (Eggerth and Gagnon 1933) Krasil'nikov 1949| "Ristella distasonis" (Eggerth and Gagnon 1933) Prevot 1938| ATCC 8503| Bacteroides distasonis| Bacteroides distasonis Eggerth and Gagnon 1933 (Approved Lists 1980)| Bacteroides fragilis subsp. distasonis| CCUG 4941| CIP 104284| DSM 20701| JCM 5825| NCTC 11152| Parabacteroides distasonis| Parabacteroides distasonis (Eggerth and Gagnon 1933) Sakamoto and Benno 2006 emend. Hahnke et al. 2016| Pseudobacterium distasonis| Ristella distasonis

1. Anti-inflammatory Effects:

   • Parabacteroides distasonis has been associated with anti-inflammatory properties. It is reported to produce molecules that can suppress inflammation in the gut. This anti-inflammatory potential may have implications for conditions characterized by chronic inflammation, such as inflammatory bowel disease (IBD) or other inflammatory disorders.

2. Metabolism and Short-Chain Fatty Acid Production:

   • Like many bacteria in the gut, Parabacteroides distasonis is involved in the fermentation of dietary fibers, leading to the production of short-chain fatty acids (SCFAs). SCFAs, particularly butyrate, have been linked to various health benefits, including maintaining the health of the intestinal epithelium and influencing metabolism.

3. Immunomodulation:

   • Research suggests that Parabacteroides distasonis may have immunomodulatory effects, influencing the activity of the immune system. This can be important for maintaining a balanced immune response and preventing excessive inflammation.

4. Association with a Healthy Gut Microbiota:

   • Parabacteroides distasonis is often found in individuals with a diverse and healthy gut microbiota. A diverse microbiota is generally considered beneficial for overall gut health and is associated with a lower risk of certain health conditions.

5. Butyrate Production:

   • Some strains of Parabacteroides distasonis have been identified as producers of butyrate. Butyrate is known for its role in providing energy to the cells lining the colon and promoting gut health.

6. Potential in Gut Dysbiosis:

   • Some studies suggest that alterations in the abundance of Parabacteroides distasonis may be associated with conditions involving gut dysbiosis, such as inflammatory bowel disease or irritable bowel syndrome. Understanding the dynamics of this species in the context of gut health is an area of ongoing research.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Parabacteroides distasonis impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.2554846405982971	0.3801124393939972	Parabacteroides phage YZ-2015a	Parent Taxa
0.23034866154193878	0.4769914746284485	Bacteroides caecimuris	Parent Taxa
0.19463740289211273	0.44118669629096985	Bacteroides thetaiotaomicron	Parent Taxa
0.19067195057868958	0.436411589384079	Bacteroides faecis	Parent Taxa
0.18679820001125336	0.42655321955680847	Bacteroides sp. CACC 737	Parent Taxa
0.1829024851322174	0.39622125029563904	Bacteroides helcogenes	Parent Taxa
0.18278256058692932	0.4206337034702301	Bacteroides sp. DH3716P	Parent Taxa
0.18001364171504974	0.4242652952671051	Bacteroides ovatus	Parent Taxa
0.1758081465959549	0.4135052561759949	Bacteroides luhongzhouii	Parent Taxa
0.172792449593544	0.41112828254699707	Bacteroides sp. A1C1	Parent Taxa
0.1704542189836502	0.41288554668426514	Phocaeicola vulgatus	Parent Taxa
0.17031194269657135	0.41264432668685913	Bacteroides xylanisolvens	Parent Taxa
0.16895288228988647	0.4055159389972687	Bacteroides humanifaecis	Parent Taxa
0.16041836142539978	0.3957196772098541	Bacteroides sp. D2	Parent Taxa
0.15398356318473816	0.38459548354148865	Bacteroides faecium	Parent Taxa
0.15232647955417633	0.3860135078430176	Bacteroides sp. M10	Parent Taxa
0.1519918292760849	0.37166061997413635	Barnesiella viscericola	Parent Taxa
0.15035578608512878	0.3810282349586487	Parabacteroides johnsonii	Parent Taxa
0.14762601256370544	0.38424283266067505	Bacteroides uniformis	Parent Taxa
0.14376045763492584	0.3728884160518646	Bacteroides nordii	Parent Taxa
0.14356772601604462	0.3784564733505249	Bacteroides salyersiae	Parent Taxa
0.14211414754390717	0.37191617488861084	Phocaeicola salanitronis	Parent Taxa
0.14159348607063293	0.3762966990470886	Phocaeicola dorei	Parent Taxa
0.13913965225219727	0.37237751483917236	Bacteroides eggerthii	Parent Taxa
0.1364278942346573	0.3690090477466583	Parabacteroides merdae	Parent Taxa
0.13458667695522308	0.33614471554756165	Parabacteroides sp. CT06	Parent Taxa
0.13099893927574158	0.3616669178009033	Odoribacter splanchnicus	Parent Taxa
0.13053452968597412	0.3612939715385437	Bacteroides caccae	Parent Taxa
0.12797679007053375	0.35279932618141174	Bacteroides sp. HF-162	Parent Taxa
0.12093350291252136	0.3477528989315033	Bacteroides fragilis	Parent Taxa
0.12006644159555435	0.336841344833374	Butyricimonas faecalis	Parent Taxa
0.12003149837255478	0.3373071551322937	Paraprevotella xylaniphila	Parent Taxa
0.11963886767625809	0.3309690058231354	Coprobacter secundus	Parent Taxa
0.11743424832820892	0.3260701298713684	Coprobacter fastidiosus	Parent Taxa
0.1161142885684967	0.34002089500427246	Bacteroides cellulosilyticus	Parent Taxa
0.1145220696926117	0.336239755153656	Parabacteroides goldsteinii	Parent Taxa
0.10936687886714935	0.33018872141838074	Bacteroides stercoris	Parent Taxa
0.10767921060323715	0.327867329120636	Bilophila wadsworthia	Parent Taxa
0.1051676943898201	0.28631603717803955	uncultured Alistipes sp.	Parent Taxa
0.10119026899337769	0.31552743911743164	Bacteroides zhangwenhongii	Parent Taxa

Other bacteria of the same rank impacting Parabacteroides distasonis

R2	Slope	Tax Name	Parent Chart
0.23034866154193878	0.482919842004776	Bacteroides caecimuris	Parent Taxa
0.19463740289211273	0.4411678910255432	Bacteroides thetaiotaomicron	Parent Taxa
0.19067195057868958	0.4369085431098938	Bacteroides faecis	Parent Taxa
0.18679820001125336	0.43792471289634705	Bacteroides sp. CACC 737	Parent Taxa
0.1829024851322174	0.46161705255508423	Bacteroides helcogenes	Parent Taxa
0.18278256058692932	0.4345409572124481	Bacteroides sp. DH3716P	Parent Taxa
0.18001364171504974	0.42429500818252563	Bacteroides ovatus	Parent Taxa
0.1758081465959549	0.42516547441482544	Bacteroides luhongzhouii	Parent Taxa
0.172792449593544	0.42028841376304626	Bacteroides sp. A1C1	Parent Taxa
0.1704542189836502	0.412836492061615	Phocaeicola vulgatus	Parent Taxa
0.17031194269657135	0.4127329885959625	Bacteroides xylanisolvens	Parent Taxa
0.16895288228988647	0.4166368246078491	Bacteroides humanifaecis	Parent Taxa
0.16041836142539978	0.405383825302124	Bacteroides sp. D2	Parent Taxa
0.15398356318473816	0.4003779888153076	Bacteroides faecium	Parent Taxa
0.15232647955417633	0.39461439847946167	Bacteroides sp. M10	Parent Taxa
0.1519918292760849	0.4089532792568207	Barnesiella viscericola	Parent Taxa
0.15035578608512878	0.3946053981781006	Parabacteroides johnsonii	Parent Taxa
0.14762601256370544	0.38419976830482483	Bacteroides uniformis	Parent Taxa
0.14376045763492584	0.3855321407318115	Bacteroides nordii	Parent Taxa
0.14356772601604462	0.3793506920337677	Bacteroides salyersiae	Parent Taxa
0.14211414754390717	0.38211336731910706	Phocaeicola salanitronis	Parent Taxa
0.14159348607063293	0.3762815296649933	Phocaeicola dorei	Parent Taxa
0.13913965225219727	0.3736521303653717	Bacteroides eggerthii	Parent Taxa
0.1364278942346573	0.3697142004966736	Parabacteroides merdae	Parent Taxa
0.13458667695522308	0.4003831744194031	Parabacteroides sp. CT06	Parent Taxa
0.13099893927574158	0.3622087836265564	Odoribacter splanchnicus	Parent Taxa
0.13053452968597412	0.3612973093986511	Bacteroides caccae	Parent Taxa
0.12797679007053375	0.3627467155456543	Bacteroides sp. HF-162	Parent Taxa
0.12093350291252136	0.3477570116519928	Bacteroides fragilis	Parent Taxa
0.12006644159555435	0.35644805431365967	Butyricimonas faecalis	Parent Taxa
0.12003149837255478	0.3558522164821625	Paraprevotella xylaniphila	Parent Taxa
0.11963886767625809	0.36148059368133545	Coprobacter secundus	Parent Taxa
0.11743424832820892	0.3601502776145935	Coprobacter fastidiosus	Parent Taxa
0.1161142885684967	0.3414916396141052	Bacteroides cellulosilyticus	Parent Taxa
0.1145220696926117	0.340596467256546	Parabacteroides goldsteinii	Parent Taxa
0.10936687886714935	0.33122536540031433	Bacteroides stercoris	Parent Taxa
0.10767921060323715	0.3284231424331665	Bilophila wadsworthia	Parent Taxa
0.1051676943898201	0.36731329560279846	uncultured Alistipes sp.	Parent Taxa
0.10119026899337769	0.3207019567489624	Bacteroides zhangwenhongii	Parent Taxa