Streptococcus milleri: NCBI 33040, [species]

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| "Streptococcus milleri" Guthof| 'Streptococcus milleri'| Streptococcus milleri

1. Commensal Bacteria:

   • Streptococcus milleri is part of the normal microbiota in various mucosal surfaces of the human body, particularly in the oral cavity and gastrointestinal tract.

2. Pathogenic Potential:

   • Despite their commensal nature, these bacteria have pathogenic potential and are known to cause a range of infections, including abscesses, cellulitis, and systemic infections. They are often associated with polymicrobial infections.

3. Abscess Formation:

   • Streptococcus milleri is frequently implicated in the formation of abscesses, especially in the abdominal and pelvic regions. Abscesses associated with these bacteria can occur in various organs, including the liver, spleen, and brain.

4. Invasive Infections:

   • In addition to localized abscesses, Streptococcus milleri can cause invasive infections, such as bacteremia (presence of bacteria in the bloodstream) and endocarditis (infection of the heart valves).

5. Clinical Presentations:

   • Streptococcus milleri infections can manifest as a variety of clinical presentations, and the severity can range from mild to severe. Common clinical presentations include respiratory infections, skin and soft tissue infections, and intra-abdominal infections.

6. Association with Other Pathogens:

   • Streptococcus milleri is often found in polymicrobial infections, meaning infections involving multiple types of bacteria. This can complicate the clinical presentation and management of infections.

7. Antibiotic Susceptibility:

   • The antibiotic susceptibility of Streptococcus milleri can vary, and appropriate antibiotic therapy is important for the treatment of infections. In some cases, these bacteria may exhibit resistance to certain antibiotics.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Streptococcus milleri impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.27533766627311707	0.6403231620788574	Corynebacterium vitaeruminis	Parent Taxa
0.16335198283195496	0.5195612907409668	Streptococcus anginosus	Parent Taxa
0.15706110000610352	0.5259905457496643	Streptococcus oralis	Parent Taxa
0.13969562947750092	0.4795980453491211	Streptococcus gordonii	Parent Taxa
0.13759207725524902	0.3911280035972595	Streptococcus sp. NSJ-72	Parent Taxa
0.13266947865486145	0.46236488223075867	Streptococcus vestibularis	Parent Taxa
0.12530560791492462	0.3611612319946289	Streptococcus periodonticum	Parent Taxa
0.1216515302658081	0.37954336404800415	Streptococcus intermedius	Parent Taxa
0.10955894738435745	0.4437243342399597	Streptococcus salivarius	Parent Taxa
0.10789935290813446	0.4282110631465912	Streptococcus sanguinis	Parent Taxa
0.10734554380178452	0.4356760084629059	Streptococcus parasanguinis	Parent Taxa
0.1031719222664833	0.31438589096069336	Streptococcus constellatus	Parent Taxa
0.10250402241945267	0.39280593395233154	Streptococcus sp. oral taxon 061	Parent Taxa
0.10080830752849579	0.37472739815711975	Streptococcus koreensis	Parent Taxa

Other bacteria of the same rank impacting Streptococcus milleri

R2	Slope	Tax Name	Parent Chart
0.3257181644439697	0.6806043386459351	Streptococcus intermedius	Parent Taxa
0.31228354573249817	0.6923152804374695	Streptococcus periodonticum	Parent Taxa
0.29804685711860657	0.705825924873352	Streptococcus constellatus	Parent Taxa
0.2909521460533142	0.6356629133224487	Streptococcus sp. NSJ-72	Parent Taxa
0.2830091714859009	0.5438671708106995	Streptococcus gordonii	Parent Taxa
0.25946947932243347	0.6414352655410767	Actinomyces israelii	Parent Taxa
0.2559930980205536	0.6186484098434448	Mogibacterium pumilum	Parent Taxa
0.16335198283195496	0.3144036829471588	Streptococcus anginosus	Parent Taxa
0.15706110000610352	0.29860058426856995	Streptococcus oralis	Parent Taxa
0.13266947865486145	0.2869367301464081	Streptococcus vestibularis	Parent Taxa
0.10955894738435745	0.24690766632556915	Streptococcus salivarius	Parent Taxa
0.10789935290813446	0.25197702646255493	Streptococcus sanguinis	Parent Taxa
0.10734554380178452	0.24638846516609192	Streptococcus parasanguinis	Parent Taxa
0.10250402241945267	0.2609533369541168	Streptococcus sp. oral taxon 061	Parent Taxa
0.10080830752849579	0.26901769638061523	Streptococcus koreensis	Parent Taxa