Sphingomonadaceae Details: NCBI 41297, gram-negative or unknown [family]

| alpha-4 proteobacteria| Sphingomonadaceae| Sphingomonadaceae Kosako et al. 2000| Sphingomonas group| Zymomonas group

1. Environmental interactions: Sphingomonadaceae bacteria play important roles in environmental processes such as biodegradation, bioremediation, and pollutant removal. They are capable of degrading a diverse array of organic compounds, including aromatic hydrocarbons, pesticides, polycyclic aromatic hydrocarbons (PAHs), and industrial chemicals. Their ability to metabolize environmental pollutants can contribute to the detoxification and degradation of contaminants in soil, water, and air, thereby mitigating environmental pollution and promoting ecosystem health.

2. Pathogenic potential: While most members of the family Sphingomonadaceae are considered non-pathogenic or opportunistic environmental bacteria, there have been rare reports of Sphingomonadaceae species causing infections in humans, particularly in immunocompromised individuals or those with underlying health conditions. Infections associated with Sphingomonadaceae bacteria include bloodstream infections, catheter-associated infections, respiratory infections, and infections associated with medical devices. However, such infections are uncommon, and Sphingomonadaceae bacteria are not typically regarded as major human pathogens.

3. Biofilm formation: Sphingomonadaceae bacteria have the ability to form biofilms on biotic and abiotic surfaces, including medical devices such as catheters and implants. Biofilm formation can promote bacterial persistence, resistance to antimicrobial agents, and evasion of host immune responses, increasing the risk of device-associated infections. Understanding the mechanisms of biofilm formation by Sphingomonadaceae bacteria may aid in the development of strategies to prevent and treat biofilm-related infections.

4. Immunomodulatory effects: Some studies suggest that exposure to Sphingomonadaceae bacteria or their components may have immunomodulatory effects on the host immune system. Certain Sphingomonadaceae species produce glycolipid antigens that can activate immune responses, particularly via interactions with specialized immune cells such as natural killer T (NKT) cells. These immunomodulatory effects may have implications for host-microbe interactions, allergic responses, and inflammatory diseases.

5. Plant-microbe interactions: Sphingomonadaceae bacteria are commonly associated with plants and are known to form symbiotic relationships with plant roots. They can promote plant growth, enhance nutrient uptake, and protect plants from pathogens and environmental stressors. Understanding the interactions between Sphingomonadaceae bacteria and plants may have applications in agriculture, horticulture, and environmental remediation.

Visuals of 2 Interactions with other bacteria of the same rank

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Sphingomonadaceae

• Lab Low and High are calculated using the formula that most labs use: Mean - 1.95 Standard Deviation to Mean + 1.95 Standard Deviation

These are values that are computed from lab specific samples and are in percentage

Lab	Frequency	Average	Median	Minimum	Maximum	Std.Dev.	Skew	25 - 75 Percentile	5 - 95 Percentile	Lab Ranges	Box-Plot-Whiskers	Harmonic Mean	Geometric Mean	Obs.
BiomeSight	0.3617	0.0048	0.002	0.001	0.528	0.0175	0.4833	0.002 - 0.004	0.001 - 0.012	-0.0294 - 0.039	-0.001 - 0.007	0.0021	0.0027	1340
BiomeSightRdp	0.4444	0.0024	0.002	0.001	0.007	0.0018	0.6823	0.001 - 0.0033	0.001 - 0.0053	-0.0012 - 0.006	-0.0024 - 0.0066	0.0016	0.0019	12
Medivere	0.8571	0.0018	0.0013	0.0006	0.0052	0.0017	1.0019	0.0007 - 0.0019	0.0006 - 0.0044	-0.0016 - 0.0052	-0.0012 - 0.0038	0.0011	0.0013	6
SequentiaBiotech	0.3889	2.4114	2.3285	0.5779	5.3372	1.4456	0.172	1.3395 - 3.1645	0.6036 - 4.5652	-0.4076 - 5.2305	-1.398 - 5.902	1.4932	1.9505	14
Thorne	0.9524	0.0278	0.0059	0.0001	1.757	0.1841	0.357	0.0035 - 0.0089	0.0012 - 0.0317	-0.3311 - 0.3867	-0.0046 - 0.017	0.0025	0.0058	180
Thryve	0.5105	0.0304	0.0043	0.0001	10.0177	0.4318	0.1812	0.0023 - 0.0087	0.001 - 0.0234	-0.8117 - 0.8725	-0.0073 - 0.0183	0.0025	0.0046	633
uBiome	0.0215	0.0168	0.0113	0.0017	0.0632	0.0177	0.9298	0.0039 - 0.0309	0.0023 - 0.0435	-0.0177 - 0.0513	-0.0366 - 0.0714	0.0056	0.0096	17
Vitract	0.1074						0	-	-	-	-			86

External Reference Ranges for Sphingomonadaceae

Sphingomonadaceae (NCBI 41297) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	1.5245172107825056E-05	0.00019011477706953883	0	0
Thorne (20/80%ile)	57.75	138.92	0.0058	0.0139

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Amino Acid and similar	2-Amino-5-(carbamoylamino)pentanoic acid {Citrulline}	1 Studies recorded. The consensus is Increases👪, Click for details.
Amino Acid and similar	N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide {Melatonin}	2 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	amikacin	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	meropenem	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	penicillin-moxalactam	1 Studies recorded. The consensus is Increases👶, Click for details.
Antibiotics, Antivirals etc	sulfamethoxazole (antibiotic)	1 Studies recorded. The consensus is Increases👪, Click for details.
Common and OTC Supplements	(N-acetyl-p-aminophenol {TYLENOL}	1 Studies recorded. The consensus is Increases👪, Click for details.
Common and OTC Supplements	long-term, moderate-intensity exercise {exercise}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Flavonoids, Polyphenols etc	Humulus lupulus compound {Xanthohumol}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Helianthus annuus {Sunflower}	1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings)	Humulus lupulus {Hops}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Hydrastis canadensis {Goldenseal}	1 Studies recorded. The consensus is Increases👪, Click for details.
Food (excluding seasonings)	nuts	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	walnuts	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine}	1 Studies recorded. The consensus is Increases👪, Click for details.
Herb or Spice	Azadirachta indica {Neem}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Ocimum tenuiflorum {Tulsi}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Vitex negundo {Nirgundi}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Zingiber officinale Roscoe {ginger}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prescription - Other	Enterococcus faecalis {Streptococcus faecalis}	1 Studies recorded. The consensus is Increases👪, Click for details.
Prescription - Other	hydromorphone	1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics	bacillus	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	bacillus licheniformis {b. licheniformis}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	bacillus,lactobacillus,streptococcus,saccharomyces probiotic	2 Studies recorded. The consensus is Increases👶👪, Click for details.
Vitamins, Minerals and similar	vitamin d	2 Studies recorded. The consensus is Increases👪📓, Click for details.
Vitamins, Minerals and similar	Zinc {Zinc Supplements}	1 Studies recorded. The consensus is Decreases👪, Click for details.

Food Groups Containing the Sphingomonadaceae bacteria

This is base on Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome. See that paper for details on foods groups.

1. fermented_meat : 100% of Highest

Foods Containing the Sphingomonadaceae bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Fontina Cheese Weight: 1.886 Passito wine Weight: 0.943 Greek style fermented table olives, Table Olives Kalamata Weight: 0.3329 Beer Sour Flanders Red Ale Weight: 0.1933 Malaysian fermented fish sauce Weight: 0.1221 Sausage, Cyprus: Limassol Weight: 0.0977 Beer Belgian Strong Dark Ale Weight: 0.0846 Gruyere cheese Weight: 0.06366 Piedmont hard cheese Weight: 0.05936 Korean soy sauce Yeongyang meju M3 1 Weight: 0.05923 Jarlsberg cheese Weight: 0.05569 Picual olives Weight: 0.04144 Lard Farm Weight: 0.04101 Brie cheese Weight: 0.02664 Liqvan cheese cheese Weight: 0.01807 Ham fermented for 4 years Weight: 0.01685 Cheddar cheese Weight: 0.01033 Stinky beans spontaneous fermentation sampling time 15 replicate 1 sample type bean Weight: 0.01004 Sausage, Cyprus: Paphos Weight: 0.007723 Swiss-Dutch-type cheese Weight: 0.006602 Dehulled maize dough, Ghana Weight: 0.004984