Mediterraneibacter gnavus: NCBI 33038, [species]

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| [Ruminococcus] gnavus| ATCC 29149| Ruminococcus gnavus| Ruminococcus gnavus Moore et al. 1976| VPI C7-9

1. Fermentation and Short-Chain Fatty Acid Production:

   • Ruminococcus gnavus, like other bacteria in the gut, is involved in the fermentation of dietary fibers and complex carbohydrates. This fermentation process results in the production of short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate. SCFAs play various roles in gut health, including providing an energy source for colonocytes and influencing immune function.

2. Metabolism of Complex Polysaccharides:

   • Ruminococcus gnavus possesses the enzymatic machinery necessary for the breakdown of complex polysaccharides. This metabolic capacity allows the bacterium to extract energy and nutrients from dietary sources that are otherwise indigestible by the host.

3. Dietary Influence:

   • The abundance and activity of Ruminococcus gnavus, like other gut bacteria, can be influenced by dietary factors. Diets rich in fiber and plant-based foods provide substrates for the fermentation processes carried out by these bacteria.

4. Associations with Health Conditions:

   • Changes in the abundance of Ruminococcus gnavus have been observed in studies of the gut microbiota in various health conditions. Alterations in the relative abundance of this species have been associated with conditions such as inflammatory bowel disease (IBD) and other gastrointestinal disorders. However, the specific roles of Ruminococcus gnavus in these conditions are still being investigated, and the relationship may be complex.

5. Immunomodulation:

   • Ruminococcus gnavus, like other members of the gut microbiota, can interact with the host's immune system. These interactions are complex and can influence immune responses in the gut.

6. Association with Mucin Degradation:

   • Some strains of Ruminococcus gnavus have been associated with the degradation of mucin, a glycoprotein that lines the gut epithelium. Mucin degradation can influence the integrity of the mucosal barrier and may be relevant in certain health conditions.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

Legend

• The interactions are based on data from 1000 healthy individuals using shotgun 10M reads Precision Biome, a provider in full conformity to EU regulations for health information
• The width of the lines indicates R² (the coefficient of determination)
• Green indicates positive slope
• Red indicates negative
• Interactions are not two way because incidence of each bacteria are different

Mediterraneibacter gnavus impacts on other bacteria of the same rank

R2	Slope	Tax Name	Parent Chart
0.5476252436637878	0.7331037521362305	Blautia argi	Parent Taxa
0.3636619448661804	0.592316210269928	Blautia hansenii	Parent Taxa
0.3478093147277832	0.5886501669883728	[Clostridium] scindens	Parent Taxa
0.3466111123561859	0.576483428478241	Blautia parvula	Parent Taxa
0.3374674916267395	0.5733177065849304	Blautia producta	Parent Taxa
0.33464139699935913	0.5780371427536011	Thomasclavelia ramosa	Parent Taxa
0.31883949041366577	0.5644579529762268	Enterocloster bolteae	Parent Taxa
0.3170260488986969	0.6374447345733643	Rothia amarae	Parent Taxa
0.3035467863082886	-0.5547027587890625	Bradyrhizobium sp. BTAi1	Parent Taxa
0.3011273145675659	0.5314652323722839	Anaerostipes caccae	Parent Taxa
0.26928335428237915	0.5054666996002197	Blautia pseudococcoides	Parent Taxa
0.26025092601776123	-0.3878878057003021	Olivibacter sp. LS-1	Parent Taxa
0.24202440679073334	0.4898640811443329	Enterocloster clostridioformis	Parent Taxa
0.24108242988586426	0.48475512862205505	Sellimonas intestinalis	Parent Taxa
0.23228819668293	0.4818515479564667	[Clostridium] innocuum	Parent Taxa
0.23210923373699188	0.4685707986354828	Amedibacterium intestinale	Parent Taxa
0.2234337478876114	0.4721739590167999	Eggerthella lenta	Parent Taxa
0.20883971452713013	0.456964910030365	Flavonifractor plautii	Parent Taxa
0.2082541137933731	0.45635807514190674	Blautia wexlerae	Parent Taxa
0.20433738827705383	0.3598550856113434	Anaerostipes rhamnosivorans	Parent Taxa
0.18178725242614746	0.3373473286628723	Allocoprobacillus halotolerans	Parent Taxa
0.16489093005657196	0.405308336019516	Hungatella hathewayi	Parent Taxa
0.16436688601970673	0.4054293930530548	Anaerostipes hadrus	Parent Taxa
0.1353270262479782	0.3564736545085907	Granulicatella adiacens	Parent Taxa
0.13196857273578644	0.3631700575351715	Clostridioides difficile	Parent Taxa
0.12760533392429352	0.3057894706726074	Eggerthella guodeyinii	Parent Taxa
0.12256959825754166	0.3437241017818451	Marvinbryantia formatexigens	Parent Taxa
0.11882730573415756	0.33814379572868347	Longicatena caecimuris	Parent Taxa
0.11258567124605179	0.3092707097530365	Gemella sanguinis	Parent Taxa
0.11121858656406403	0.2872912287712097	Clostridium sp. C1	Parent Taxa
0.10806528478860855	0.24133287370204926	Peptacetobacter hiranonis	Parent Taxa
0.10759039223194122	0.32757627964019775	Blautia sp. SC05B48	Parent Taxa
0.10673048347234726	0.30112162232398987	Mogibacterium diversum	Parent Taxa
0.10461104661226273	0.29006993770599365	Ruminococcus gauvreauii	Parent Taxa

Other bacteria of the same rank impacting Mediterraneibacter gnavus

R2	Slope	Tax Name	Parent Chart
0.5476252436637878	0.7469955086708069	Blautia argi	Parent Taxa
0.3636619448661804	0.6139659285545349	Blautia hansenii	Parent Taxa
0.3478093147277832	0.5908591151237488	[Clostridium] scindens	Parent Taxa
0.3466111123561859	0.6012507677078247	Blautia parvula	Parent Taxa
0.3374674916267395	0.5886221528053284	Blautia producta	Parent Taxa
0.33464139699935913	0.5789270997047424	Thomasclavelia ramosa	Parent Taxa
0.31883949041366577	0.5648595690727234	Enterocloster bolteae	Parent Taxa
0.3011273145675659	0.5665983557701111	Anaerostipes caccae	Parent Taxa
0.26928335428237915	0.5327420234680176	Blautia pseudococcoides	Parent Taxa
0.24202440679073334	0.4940643906593323	Enterocloster clostridioformis	Parent Taxa
0.24108242988586426	0.4973282516002655	Sellimonas intestinalis	Parent Taxa
0.23228819668293	0.48207417130470276	[Clostridium] innocuum	Parent Taxa
0.23210923373699188	0.4953557252883911	Amedibacterium intestinale	Parent Taxa
0.2234337478876114	0.4732021987438202	Eggerthella lenta	Parent Taxa
0.20883971452713013	0.4570147395133972	Flavonifractor plautii	Parent Taxa
0.2082541137933731	0.4563392698764801	Blautia wexlerae	Parent Taxa
0.20433738827705383	0.5678324699401855	Anaerostipes rhamnosivorans	Parent Taxa
0.18178725242614746	0.5388726592063904	Allocoprobacillus halotolerans	Parent Taxa
0.16489093005657196	0.406828373670578	Hungatella hathewayi	Parent Taxa
0.16436688601970673	0.40541431307792664	Anaerostipes hadrus	Parent Taxa
0.1353270262479782	0.3796270191669464	Granulicatella adiacens	Parent Taxa
0.13196857273578644	0.3633795380592346	Clostridioides difficile	Parent Taxa
0.12760533392429352	0.41729801893234253	Eggerthella guodeyinii	Parent Taxa
0.12256959825754166	0.35659295320510864	Marvinbryantia formatexigens	Parent Taxa
0.11882730573415756	0.35141056776046753	Longicatena caecimuris	Parent Taxa
0.11258567124605179	0.3640359938144684	Gemella sanguinis	Parent Taxa
0.11121858656406403	0.38712838292121887	Clostridium sp. C1	Parent Taxa
0.10806528478860855	0.4477851688861847	Peptacetobacter hiranonis	Parent Taxa
0.10759039223194122	0.3284437954425812	Blautia sp. SC05B48	Parent Taxa
0.10673048347234726	0.35444310307502747	Mogibacterium diversum	Parent Taxa
0.10461104661226273	0.3606407642364502	Ruminococcus gauvreauii	Parent Taxa