Fusobacteriota Details: NCBI 32066, gram-negative or unknown [phylum]

| Fusobacteraeota| Fusobacteraeota Oren et al. 2015| Fusobacteria| Fusobacteria Garrity and Holt 2001| Fusobacteriota

1. Oral health: Fusobacteriota species are common inhabitants of the human oral cavity and are part of the oral microbiota. While they are typically commensal and play roles in normal oral microbial communities, certain species, such as Fusobacterium nucleatum, have been implicated in periodontal diseases. Fusobacterium nucleatum can contribute to the formation of dental plaque and biofilms, leading to periodontitis, gingivitis, and other oral health issues. Additionally, Fusobacterium species have been detected in dental abscesses and oral infections.

2. Systemic infections: Fusobacteriota species, particularly Fusobacterium necrophorum, have been associated with systemic infections such as Lemierre's syndrome. Lemierre's syndrome is a rare but serious condition characterized by septic thrombophlebitis of the internal jugular vein, often following an acute oropharyngeal infection. Fusobacterium necrophorum can spread from the oral cavity or pharynx to deeper tissues and the bloodstream, leading to septicemia and the formation of septic thrombi in the neck veins.

3. Inflammatory bowel disease (IBD): Emerging research suggests that Fusobacteriota species may play a role in the pathogenesis of inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis. While the exact mechanisms are not fully understood, Fusobacterium species have been detected in the gut mucosa of individuals with IBD, and their presence has been associated with intestinal inflammation and disease severity. However, the causal relationship between Fusobacteriota and IBD requires further investigation.

4. Colorectal cancer: Fusobacteriota, particularly Fusobacterium nucleatum, has been implicated in the development and progression of colorectal cancer (CRC). Studies have found an association between increased abundance of Fusobacterium nucleatum in colorectal tumors and poorer clinical outcomes in CRC patients. Fusobacterium nucleatum may promote tumorigenesis through various mechanisms, including modulation of the immune response, promotion of inflammation, and interaction with tumor cells. However, the exact role of Fusobacteriota in CRC pathogenesis is still being elucidated.

5. Other infections: Fusobacteriota species have been implicated in various other infections, including brain abscesses, septic arthritis, respiratory tract infections, and genital infections. Fusobacteriota may act as opportunistic pathogens, particularly in individuals with predisposing factors such as immunodeficiency, trauma, or underlying medical conditions.

The above data is from 1000 Healthy Individuals done using Shotgun(10 Millions reads) provide courtesy of Precision Biome.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Fusobacteriota

• Lab Low and High are calculated using the formula that most labs use: Mean - 1.95 Standard Deviation to Mean + 1.95 Standard Deviation

These are values that are computed from lab specific samples and are in percentage

Lab	Frequency	Average	Median	Minimum	Maximum	Std.Dev.	Skew	25 - 75 Percentile	5 - 95 Percentile	Lab Ranges	Box-Plot-Whiskers	Harmonic Mean	Geometric Mean	Obs.
BiomeSight	0.5139	0.2637	0.004	0.001	27.252	1.6151	0.4823	0.002 - 0.012	0.001 - 0.4977	-2.8857 - 3.4131	-0.013 - 0.027	0.003	0.007	1904
BiomeSightRdp	0.2963	0.2066	0.002	0.001	1.641	0.5796	1.0592	0.0018 - 0.002	0.001 - 1.0673	-0.9235 - 1.3368	0.0014 - 0.0024	0.0018	0.0039	8
custom	0.4894	0.5767	0.183	0.0001	1.778	0.7602	1.5535	0.0077 - 1.389	0.0003 - 1.778	-0.9057 - 2.0591	-2.0641 - 3.4609	0.0011	0.0676	23
es-xenogene	0.9545	0.1005	0.05	0.01	0.539	0.1234	1.2262	0.018 - 0.113	0.0116 - 0.23	-0.1403 - 0.3412	-0.1245 - 0.2555	0.0308	0.054	21
Medivere	0.8571	0.0256	0.0068	0.0012	0.0944	0.0368	1.5294	0.0035 - 0.033	0.0017 - 0.081	-0.0462 - 0.0973	-0.0406 - 0.0772	0.004	0.0092	6
SequentiaBiotech	0.1944	0.6414	0.122	0.0208	3.6917	1.3493	1.1548	0.0589 - 0.2688	0.0322 - 2.685	-1.9898 - 3.2727	-0.256 - 0.5838	0.0711	0.1555	7
Thorne	0.9471	0.0118	0.0062	0.0004	0.3121	0.0296	0.5709	0.0043 - 0.0108	0.0022 - 0.0295	-0.0459 - 0.0696	-0.0055 - 0.0206	0.0047	0.0068	179
Thryve	0.5266	0.2591	0.0047	0.0001	18.2006	1.5361	0.4968	0.0023 - 0.0131	0.001 - 0.5449	-2.7364 - 3.2545	-0.0139 - 0.0293	0.0029	0.008	653
uBiome	0.1838	0.8149	0.0134	0.002	23.393	2.862	0.8401	0.0053 - 0.1246	0.0023 - 5.9485	-4.7661 - 6.3958	-0.1736 - 0.3035	0.0082	0.0318	145
Vitract	0.4844	0.0092	0.0092	0.0024	0.0161	0.0097	0	0.0058 - 0.0127	0.0031 - 0.0154	-0.0096 - 0.0281	-0.0044 - 0.0229	0.8104	0.0062	388

External Reference Ranges for Fusobacteriota

Fusobacteriota (NCBI 32066) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
Medivere	0	30	0	0.003
GanzImmun Diagostics	0	40	0	0.004
Lab Teletest	0	500	0	0.05
Jason Hawrelak	0	9000	0	0.9
XenoGene	0	10000	0	1
Jason Hawrelak	0	90000000	0	9000
PrecisionBiome	6.749069871148095E-05	0.014528036117553711	0	0
Thorne (20/80%ile)	27.11	60.15	0.0027	0.006
Nirvana/CosmosId	200	2500	0.02	0.25

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Diet Style	dietary fiber	1 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style	High glycemic diet {High-sugar diet (HSD)}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	hypocaloric hyperproteic diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	Slow digestible carbohydrates. {Low Glycemic}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style	Traditional Mediterranean diet {Mediterranean diet}	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	whole-grain diet	2 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	amaranthus {amaranth}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Avena sativa {Oats}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Avena sativa x Hordeum vulgare {barley,oat}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Bovine Milk Products {Dairy}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Brassica oleracea var. italica {Broccoli}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Citrus aurantiifolia {Lime}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Citrus limon {Lemon}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	gliadin, glutenin etc {Gluten}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Hydrastis canadensis {Goldenseal}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	Phaseolus vulgaris {Boston bean}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	pseudo-cereals {amaranth,quinoa, taro,buckwheat}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Salvia hispanica {Chia Seeds}	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	soy	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Sulforaphane {Dark Greens}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	yogurt	2 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Zea mays {maize}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine}	2 Studies recorded. The consensus is Increases👶📓, Click for details.
Herb or Spice	Diferuloylmethane {Curcumin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items	3-Methylbutanoic acid {isovaleric acid}	1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items	2,3-dihydroxypropyl dodecanoate {Monolaurin}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Miscellaneous, food additives, and other odd items	Cholestyramine,Colesevelam,Colestipol {Bile Acid Sequestrant}	1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items	Tobacco consumption {Smoking}	2 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	(2->1)-beta-D-fructofuranan {Inulin}	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	Plantago {Psyllium}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar	ß-glucan {Beta-Glucan}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prescription - Other	Enterococcus faecalis {Streptococcus faecalis}	1 Studies recorded. The consensus is Increases👶, Click for details.
Prescription - Other	moviprep (prescription)	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	bacillus	1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics	Bacillus amyloliquefaciens group {B. Amyloliquefaciens}	1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics	bacillus,lactobacillus,streptococcus,saccharomyces probiotic	2 Studies recorded. The consensus is Increases👶👪, Click for details.
Probiotics	bifidobacterium	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	bifidobacterium bifidum {B. bifidum}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	enterococcus faecium {E. faecium}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Lacticaseibacillus rhamnosus {l. rhamnosus}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Lactococcus lactis {Streptococcus lactis}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Latilactobacillus sakei {Lactobacillus sakei}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Limosilactobacillus reuteri {L. Reuteri}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	pediococcus acidilactici {P acidilactici}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Pediococcus pentosaceus {P. pentosaceus}	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Probiotic Mixture 1 {Japanese Vet Probiotic}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Probiotic Mixture 2 {Vetafarm Probotic}	2 Studies recorded. The consensus is Decreases👶, Click for details.
Sugar and similar	N-acetylneuraminic acid {Sialic acid}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	alpha-tocopherol {Vitamin E}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	ascorbic acid {Vitamin C}	1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Mixture of Vitamin B? {B Vitamins}	2 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar	Riboflavin {Vitamin B2}	1 Studies recorded. The consensus is Decreases👶, Click for details.